hu.MAP 2.0: Complex View
Human Protein Complex Map
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Complex: HuMAP2_02005
Confidence: Medium
Proteins| Genename | Protein Name | Links |
|---|---|---|
| ALKBH8 | Alkylated DNA repair protein alkB homolog 8 (EC 1.14.11.-) (Probable alpha-ketoglutarate-dependent dioxygenase ABH8) (S-adenosyl-L-methionine-dependent tRNA methyltransferase ABH8) (tRNA (carboxymethyluridine(34)-5-O)-methyltransferase ABH8) (EC 2.1.1.229) | UniProt NCBI |
| MMP26 | Matrix metalloproteinase-26 (MMP-26) (EC 3.4.24.-) (Endometase) (Matrilysin-2) | UniProt NCBI |
| TIMP2 | Metalloproteinase inhibitor 2 (CSC-21K) (Tissue inhibitor of metalloproteinases 2) (TIMP-2) | UniProt NCBI |
| FECH | Ferrochelatase, mitochondrial (EC 4.99.1.1) (Heme synthase) (Protoheme ferro-lyase) | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| WP:WP129 | 0.000588391449758 | 0.5 | MMP26 TIMP2 | Matrix Metalloproteinases |
Edges
| Protein 1 | Protein 2 | Score | Precision | Evidence |
|---|---|---|---|---|
| ALKBH8 | FECH | 0.292 | 0.493 | bioplex (FECH) bioplex_WMM |
| TIMP2 | FECH | 0.196 | 0.449 | bioplex (TIMP2) bioplex_WMM |
| MMP26 | FECH | 0.035 | 0.261 | bioplex (MMP26) bioplex_WMM |
Images
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Complex HuMAP2_02005 has an average edge precision of 0.401 which is ranked 3309 out of all 6965 complexes.
Related Complexes
| Genename | Complexes |
|---|---|
| ALKBH8 | HuMAP2_02005 HuMAP2_02826 |
| MMP26 | HuMAP2_02005 |
| TIMP2 | HuMAP2_01361 HuMAP2_02005 HuMAP2_02826 HuMAP2_06424 |
| FECH | HuMAP2_02005 HuMAP2_02826 |