hu.MAP 2.0: Complex View
Human Protein Complex Map
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Complex: HuMAP2_02009
Confidence: Medium
Proteins| Genename | Protein Name | Links |
|---|---|---|
| SH3BP4 | SH3 domain-binding protein 4 (EH-binding protein 10) (Transferrin receptor-trafficking protein) | UniProt NCBI |
| NTRK3 | NT-3 growth factor receptor (EC 2.7.10.1) (GP145-TrkC) (Trk-C) (Neurotrophic tyrosine kinase receptor type 3) (TrkC tyrosine kinase) | UniProt NCBI |
| PTPRS | Receptor-type tyrosine-protein phosphatase S (R-PTP-S) (EC 3.1.3.48) (Receptor-type tyrosine-protein phosphatase sigma) (R-PTP-sigma) | UniProt NCBI |
| GIPC2 | PDZ domain-containing protein GIPC2 | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| REAC:R-HSA-9034015 | 0.000914071346391 | 0.5 | PTPRS NTRK3 | Signaling by NTRK3 (TRKC) |
| REAC:R-HSA-388844 | 0.00153629461685 | 0.5 | PTPRS NTRK3 | Receptor-type tyrosine-protein phosphatases |
| REAC:R-HSA-6794362 | 0.0323499619092 | 0.5 | PTPRS NTRK3 | Protein-protein interactions at synapses |
| REAC:R-HSA-166520 | 0.0408500448467 | 0.5 | PTPRS NTRK3 | Signaling by NTRKs |
Edges
| Protein 1 | Protein 2 | Score | Precision | Evidence |
|---|---|---|---|---|
| NTRK3 | PTPRS | 0.102 | 0.365 | bioplex (NTRK3) bioplex_WMM |
| NTRK3 | SH3BP4 | 0.089 | 0.352 | bioplex (NTRK3) bioplex_WMM |
| GIPC2 | SH3BP4 | 0.028 | 0.231 | bioplex (GIPC2) bioplex_WMM |
| PTPRS | SH3BP4 | 0.007 | 0.002 | bioplex_WMM WMM_only |
Images
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Complex HuMAP2_02009 has an average edge precision of 0.237 which is ranked 5578 out of all 6965 complexes.
Related Complexes
| Genename | Complexes |
|---|---|
| SH3BP4 | HuMAP2_02009 HuMAP2_02447 |
| NTRK3 | HuMAP2_02009 HuMAP2_02447 |
| PTPRS | HuMAP2_02009 HuMAP2_02447 |
| GIPC2 | HuMAP2_02009 HuMAP2_02802 HuMAP2_03254 |