hu.MAP 2.0: Complex View
Human Protein Complex Map
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Complex: HuMAP2_02022
Confidence: Medium High
Proteins| Genename | Protein Name | Links |
|---|---|---|
| WDR59 | GATOR complex protein WDR59 (WD repeat-containing protein 59) | UniProt NCBI |
| GRB10 | Growth factor receptor-bound protein 10 (GRB10 adapter protein) (Insulin receptor-binding protein Grb-IR) | UniProt NCBI |
| UEVLD | Ubiquitin-conjugating enzyme E2 variant 3 (UEV-3) (EV and lactate/malate dehydrogenase domain-containing protein) | UniProt NCBI |
| NRF1 | Nuclear respiratory factor 1 (NRF-1) (Alpha palindromic-binding protein) (Alpha-pal) | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| KEGG:04150 | 0.0203683297936 | 0.5 | WDR59 GRB10 | mTOR signaling pathway |
| HPA:007020_22 | 0.025758723693 | 1.0 | UEVLD NRF1 WDR59 GRB10 | cerebellum; cells in granular layer[Approved,Medium] |
Edges
| Protein 1 | Protein 2 | Score | Precision | Evidence |
|---|---|---|---|---|
| WDR59 | GRB10 | 0.545 | 0.642 | bioplex (WDR59) bioplex_WMM |
| WDR59 | NRF1 | 0.416 | 0.573 | bioplex (WDR59) bioplex_WMM |
| UEVLD | WDR59 | 0.076 | 0.357 | bioplex (WDR59) bioplex_WMM |
| GRB10 | NRF1 | 0.009 | 0.095 | bioplex_WMM WMM_only |
| UEVLD | GRB10 | 0.008 | 0.091 | bioplex_WMM WMM_only |
| UEVLD | NRF1 | 0.008 | 0.091 | bioplex_WMM WMM_only |
Images
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Complex HuMAP2_02022 has an average edge precision of 0.308 which is ranked 4474 out of all 6965 complexes.
Related Complexes
| Genename | Complexes |
|---|---|
| WDR59 | HuMAP2_02022 HuMAP2_03116 HuMAP2_03792 |
| GRB10 | HuMAP2_02022 HuMAP2_03116 |
| UEVLD | HuMAP2_02022 |
| NRF1 | HuMAP2_02022 |