hu.MAP 2.0: Complex View
Human Protein Complex Map
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Complex: HuMAP2_02030
Confidence: Extremely High
Proteins| Genename | Protein Name | Links |
|---|---|---|
| ATP5F1A | ATP synthase subunit alpha, mitochondrial (ATP synthase F1 subunit alpha) | UniProt NCBI |
| ATP5F1B | ATP synthase subunit beta, mitochondrial (EC 7.1.2.2) (ATP synthase F1 subunit beta) | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| CORUM:563 | 0.000201110815485 | 1.0 | ATP5F1B ATP5F1A | F1F0-ATP synthase, mitochondrial |
| REAC:R-HSA-163210 | 0.000256416289743 | 1.0 | ATP5F1B ATP5F1A | Formation of ATP by chemiosmotic coupling |
| WP:WP623 | 0.000553283277601 | 1.0 | ATP5F1B ATP5F1A | Oxidative phosphorylation |
| REAC:R-HSA-8949613 | 0.000729026706133 | 1.0 | ATP5F1B ATP5F1A | Cristae formation |
| KEGG:00190 | 0.00100713074717 | 1.0 | ATP5F1B ATP5F1A | Oxidative phosphorylation |
| KEGG:05012 | 0.00114894316007 | 1.0 | ATP5F1B ATP5F1A | Parkinson disease |
| WP:WP111 | 0.00159390293709 | 1.0 | ATP5F1B ATP5F1A | Electron Transport Chain (OXPHOS system in mitochondria) |
| KEGG:05010 | 0.00171881896746 | 1.0 | ATP5F1B ATP5F1A | Alzheimer disease |
| KEGG:05016 | 0.00224682217969 | 1.0 | ATP5F1B ATP5F1A | Huntington disease |
| GO:0043532 | 0.00270494046827 | 1.0 | ATP5F1B ATP5F1A | angiostatin binding |
| REAC:R-HSA-1268020 | 0.0029663845284 | 1.0 | ATP5F1B ATP5F1A | Mitochondrial protein import |
| KEGG:04714 | 0.00317122901933 | 1.0 | ATP5F1B ATP5F1A | Thermogenesis |
| GO:0045261 | 0.00450823411379 | 1.0 | ATP5F1B ATP5F1A | proton-transporting ATP synthase complex, catalytic core F(1) |
| REAC:R-HSA-1592230 | 0.00641543501397 | 1.0 | ATP5F1B ATP5F1A | Mitochondrial biogenesis |
| REAC:R-HSA-163200 | 0.011178409494 | 1.0 | ATP5F1B ATP5F1A | Respiratory electron transport, ATP synthesis by chemiosmotic coupling, and heat production by uncoupling proteins. |
| GO:0033178 | 0.0126230555186 | 1.0 | ATP5F1B ATP5F1A | proton-transporting two-sector ATPase complex, catalytic domain |
| REAC:R-HSA-9609507 | 0.0177396498492 | 1.0 | ATP5F1B ATP5F1A | Protein localization |
| GO:0042288 | 0.020287053512 | 1.0 | ATP5F1B ATP5F1A | MHC class I protein binding |
| REAC:R-HSA-1428517 | 0.0226752444459 | 1.0 | ATP5F1B ATP5F1A | The citric acid (TCA) cycle and respiratory electron transport |
| GO:0046933 | 0.029754345151 | 1.0 | ATP5F1B ATP5F1A | proton-transporting ATP synthase activity, rotational mechanism |
Edges
| Protein 1 | Protein 2 | Score | Precision | Evidence |
|---|---|---|---|---|
| ATP5F1A | ATP5F1B | 1.0 | 0.949 | hein_WMM bioplex (ATP5F1B) bioplex_WMM Guru boldt hein (ATP5F1A) Malo fraction boldt_WMM treiber_WMM |
Images
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Complex HuMAP2_02030 has an average edge precision of 0.949 which is ranked 5 out of all 6965 complexes.
Related Complexes
| Genename | Complexes |
|---|---|
| ATP5F1A | HuMAP2_00218 HuMAP2_02030 HuMAP2_02410 HuMAP2_03970 HuMAP2_04624 HuMAP2_06081 |
| ATP5F1B | HuMAP2_00218 HuMAP2_01266 HuMAP2_02030 HuMAP2_02410 HuMAP2_03970 HuMAP2_04624 HuMAP2_06081 |