hu.MAP 2.0: Complex View
Human Protein Complex Map
Search for a protein
Complex: HuMAP2_02043
Confidence: Very High
Proteins| Genename | Protein Name | Links |
|---|---|---|
| KAT7 | Histone acetyltransferase KAT7 (EC 2.3.1.48) (Histone acetyltransferase binding to ORC1) (Lysine acetyltransferase 7) (MOZ, YBF2/SAS3, SAS2 and TIP60 protein 2) (MYST-2) | UniProt NCBI |
| JADE2 | E3 ubiquitin-protein ligase Jade-2 (EC 2.3.2.27) (Jade family PHD finger protein 2) (PHD finger protein 15) | UniProt NCBI |
| ING4 | Inhibitor of growth protein 4 (p29ING4) | UniProt NCBI |
| ING5 | Inhibitor of growth protein 5 (p28ING5) | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| CORUM:2847 | 2.70078815927e-09 | 0.75 | JADE2 KAT7 ING4 | ING4 complex (ING4, JADE2, KAT7, MEAF6) |
| CORUM:7254 | 2.70078815927e-09 | 0.75 | JADE2 KAT7 ING5 | ING5 complex (ING5, JADE2, KAT7, MEAF6) |
| REAC:R-HSA-3214847 | 1.47230432248e-06 | 1.0 | JADE2 ING4 KAT7 ING5 | HATs acetylate histones |
| GO:0043966 | 5.61829777936e-06 | 1.0 | JADE2 ING4 KAT7 ING5 | histone H3 acetylation |
| GO:0043983 | 7.26438828159e-06 | 0.75 | JADE2 KAT7 ING4 | histone H4-K12 acetylation |
| REAC:R-HSA-4839726 | 1.93476074015e-05 | 1.0 | JADE2 ING4 KAT7 ING5 | Chromatin organization |
| REAC:R-HSA-3247509 | 1.93476074015e-05 | 1.0 | JADE2 ING4 KAT7 ING5 | Chromatin modifying enzymes |
| CORUM:2858 | 3.01612206104e-05 | 0.5 | ING5 KAT7 | ING5 complex (ING5, JADE1, KAT7, MEAF6) |
| CORUM:2848 | 3.01612206104e-05 | 0.5 | ING4 KAT7 | ING4 complex (ING4, JADE3, KAT7, MEAF6) |
| CORUM:1352 | 3.01612206104e-05 | 0.5 | ING4 KAT7 | ING4 complex (ING4, JADE1, KAT7, MEAF6) |
| CORUM:7255 | 3.01612206104e-05 | 0.5 | ING5 KAT7 | ING5 complex (ING5, JADE3, KAT7, MEAF6) |
| GO:0000123 | 3.47984386015e-05 | 1.0 | JADE2 ING4 KAT7 ING5 | histone acetyltransferase complex |
| GO:1902493 | 5.68877655611e-05 | 1.0 | JADE2 ING4 KAT7 ING5 | acetyltransferase complex |
| GO:0031248 | 5.68877655611e-05 | 1.0 | JADE2 ING4 KAT7 ING5 | protein acetyltransferase complex |
| GO:0016573 | 0.000125895977869 | 1.0 | JADE2 ING4 KAT7 ING5 | histone acetylation |
| GO:0018393 | 0.000135718631087 | 1.0 | JADE2 ING4 KAT7 ING5 | internal peptidyl-lysine acetylation |
| GO:0006475 | 0.000162788555852 | 1.0 | JADE2 ING4 KAT7 ING5 | internal protein amino acid acetylation |
| GO:0043981 | 0.000165189908538 | 0.75 | JADE2 KAT7 ING4 | histone H4-K5 acetylation |
| GO:0043982 | 0.000165189908538 | 0.75 | JADE2 KAT7 ING4 | histone H4-K8 acetylation |
| GO:0018394 | 0.000168654810117 | 1.0 | JADE2 ING4 KAT7 ING5 | peptidyl-lysine acetylation |
| GO:0006473 | 0.000455512457831 | 1.0 | JADE2 ING4 KAT7 ING5 | protein acetylation |
| GO:0043543 | 0.00107888479641 | 1.0 | JADE2 ING4 KAT7 ING5 | protein acylation |
| GO:0018205 | 0.00665909549353 | 1.0 | JADE2 ING4 KAT7 ING5 | peptidyl-lysine modification |
| GO:0043967 | 0.00848863295691 | 0.75 | JADE2 KAT7 ING4 | histone H4 acetylation |
| GO:0016570 | 0.0111323368581 | 1.0 | JADE2 ING4 KAT7 ING5 | histone modification |
| GO:0016569 | 0.0133451908966 | 1.0 | JADE2 ING4 KAT7 ING5 | covalent chromatin modification |
Edges
| Protein 1 | Protein 2 | Score | Precision | Evidence |
|---|---|---|---|---|
| JADE2 | ING4 | 1.0 | 0.949 | hein_WMM bioplex (JADE2) bioplex_WMM hein (ING4) |
| KAT7 | JADE2 | 1.0 | 0.949 | hein_WMM bioplex (JADE2) bioplex_WMM |
| JADE2 | ING5 | 0.994 | 0.919 | bioplex (JADE2) bioplex_WMM |
| KAT7 | ING5 | 0.045 | 0.284 | hein_WMM bioplex (KAT7) bioplex_WMM |
| KAT7 | ING4 | 0.028 | 0.229 | hein_WMM bioplex_WMM hein (ING4) |
| ING5 | ING4 | 0.011 | 0.137 | bioplex_WMM WMM_only |
Images
Click to enlarge
Complex HuMAP2_02043 has an average edge precision of 0.578 which is ranked 2046 out of all 6965 complexes.
Related Complexes
| Genename | Complexes |
|---|---|
| KAT7 | HuMAP2_00963 HuMAP2_02043 HuMAP2_06324 HuMAP2_06383 |
| JADE2 | HuMAP2_00983 HuMAP2_02043 HuMAP2_06383 |
| ING4 | HuMAP2_00983 HuMAP2_02043 HuMAP2_06383 |
| ING5 | HuMAP2_00983 HuMAP2_02043 HuMAP2_06383 |