hu.MAP 2.0: Complex View
Human Protein Complex Map
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Complex: HuMAP2_02044
Confidence: Medium High
Proteins| Genename | Protein Name | Links |
|---|---|---|
| ZHX2 | Zinc fingers and homeoboxes protein 2 (Alpha-fetoprotein regulator 1) (AFP regulator 1) (Regulator of AFP) (Zinc finger and homeodomain protein 2) | UniProt NCBI |
| ELMO2 | Engulfment and cell motility protein 2 (Protein ced-12 homolog A) (hCed-12A) | UniProt NCBI |
| ANKRD54 | Ankyrin repeat domain-containing protein 54 (Lyn-interacting ankyrin repeat protein) | UniProt NCBI |
| ELMO1 | Engulfment and cell motility protein 1 (Protein ced-12 homolog) | UniProt NCBI |
| ELMO3 | Engulfment and cell motility protein 3 | UniProt NCBI |
| DOCK5 | Dedicator of cytokinesis protein 5 | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| KEGG:05131 | 6.94278084771e-05 | 0.5 | ELMO3 ELMO2 ELMO1 | Shigellosis |
| KEGG:05100 | 0.000103500544784 | 0.5 | ELMO3 ELMO2 ELMO1 | Bacterial invasion of epithelial cells |
| REAC:R-HSA-8849471 | 0.00172598429993 | 0.333333333333 | ELMO1 ELMO2 | PTK6 Regulates RHO GTPases, RAS GTPase and MAP kinases |
| REAC:R-HSA-9006927 | 0.0227674337622 | 0.333333333333 | ELMO1 ELMO2 | Signaling by Non-Receptor Tyrosine Kinases |
| REAC:R-HSA-8848021 | 0.0227674337622 | 0.333333333333 | ELMO1 ELMO2 | Signaling by PTK6 |
| REAC:R-HSA-2029482 | 0.0375501136505 | 0.333333333333 | ELMO1 ELMO2 | Regulation of actin dynamics for phagocytic cup formation |
| CORUM:5337 | 0.0499726005494 | 0.166666666667 | ELMO1 | ELMO1-DOCK1 complex |
| CORUM:5341 | 0.0499726005494 | 0.166666666667 | ELMO1 | ELMO1-DOCK2 complex |
Edges
| Protein 1 | Protein 2 | Score | Precision | Evidence |
|---|---|---|---|---|
| ELMO1 | DOCK5 | 1.0 | 0.949 | bioplex (DOCK5,ELMO1) bioplex_WMM |
| ELMO2 | ELMO1 | 0.99 | 0.909 | bioplex (ELMO1) bioplex_WMM |
| DOCK5 | ZHX2 | 0.957 | 0.863 | bioplex (DOCK5) bioplex_WMM |
| ELMO2 | DOCK5 | 0.936 | 0.85 | hein_WMM bioplex (DOCK5) bioplex_WMM |
| DOCK5 | ELMO3 | 0.113 | 0.381 | bioplex (ELMO3) bioplex_WMM |
| ANKRD54 | DOCK5 | 0.095 | 0.359 | bioplex (DOCK5) bioplex_WMM |
| ELMO2 | ELMO3 | 0.011 | 0.142 | bioplex (ELMO3) bioplex_WMM |
| ELMO1 | ZHX2 | 0.008 | 0.067 | bioplex_WMM WMM_only |
| ANKRD54 | ZHX2 | 0.008 | 0.06 | bioplex_WMM WMM_only |
| ELMO2 | ZHX2 | 0.008 | 0.047 | bioplex_WMM WMM_only |
| ANKRD54 | ELMO1 | 0.008 | 0.04 | bioplex_WMM WMM_only |
| ANKRD54 | ELMO2 | 0.008 | 0.027 | bioplex_WMM WMM_only |
| ELMO1 | ELMO3 | 0.006 | 0.004 | bioplex (ELMO3) bioplex_WMM |
Images
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Complex HuMAP2_02044 has an average edge precision of 0.361 which is ranked 3738 out of all 6965 complexes.
Related Complexes