hu.MAP 2.0: Complex View
Human Protein Complex Map
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Complex: HuMAP2_02069
Confidence: Extremely High
Proteins| Genename | Protein Name | Links |
|---|---|---|
| WDR77 | Methylosome protein 50 (MEP-50) (Androgen receptor cofactor p44) (WD repeat-containing protein 77) (p44/Mep50) | UniProt NCBI |
| PRMT5 | Protein arginine N-methyltransferase 5 (EC 2.1.1.320) (72 kDa ICln-binding protein) (Histone-arginine N-methyltransferase PRMT5) (Jak-binding protein 1) (Shk1 kinase-binding protein 1 homolog) (SKB1 homolog) (SKB1Hs) [Cleaved into: Protein arginine N-methyltransferase 5, N-terminally processed] | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| CORUM:837 | 5.02777038712e-06 | 1.0 | PRMT5 WDR77 | MEP50-PRMT5-ICLN complex |
| CORUM:2838 | 5.02777038712e-06 | 1.0 | PRMT5 WDR77 | MEP50-PRMT5-ICLN complex |
| CORUM:6858 | 1.67592346237e-05 | 1.0 | PRMT5 WDR77 | CHTOP-methylosome complex |
| CORUM:810 | 3.51943927099e-05 | 1.0 | PRMT5 WDR77 | FCP1-associated protein complex |
| CORUM:811 | 3.51943927099e-05 | 1.0 | PRMT5 WDR77 | FCP1-associated protein complex |
| REAC:R-HSA-194441 | 0.00205300624141 | 1.0 | PRMT5 WDR77 | Metabolism of non-coding RNA |
| REAC:R-HSA-191859 | 0.00205300624141 | 1.0 | PRMT5 WDR77 | snRNP Assembly |
| REAC:R-HSA-3214858 | 0.00503279815751 | 1.0 | PRMT5 WDR77 | RMTs methylate histone arginines |
| CORUM:1748 | 0.0249595281251 | 0.5 | PRMT5 | PRMT5 complex |
| CORUM:2764 | 0.0249595281251 | 0.5 | PRMT5 | PRMT5 complex |
| GO:0034709 | 0.029754345151 | 1.0 | PRMT5 WDR77 | methylosome |
| CORUM:836 | 0.0499173803268 | 0.5 | PRMT5 | 20S methyltransferase core complex |
| CORUM:6853 | 0.0499173803268 | 0.5 | PRMT5 | COPRS-PRMT5 complex |
| CORUM:7410 | 0.0499173803268 | 0.5 | PRMT5 | CAPG-PRMT5 complex |
Edges
| Protein 1 | Protein 2 | Score | Precision | Evidence |
|---|---|---|---|---|
| WDR77 | PRMT5 | 1.0 | 0.949 | hein_WMM bioplex (WDR77) bioplex_WMM boldt youn_WMM hein (PRMT5) Malo gupta_WMM fraction boldt_WMM |
Images
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Complex HuMAP2_02069 has an average edge precision of 0.949 which is ranked 5 out of all 6965 complexes.
Related Complexes
| Genename | Complexes |
|---|---|
| WDR77 | HuMAP2_02069 HuMAP2_04365 HuMAP2_04507 HuMAP2_05928 HuMAP2_06950 |
| PRMT5 | HuMAP2_02069 HuMAP2_04365 HuMAP2_04507 HuMAP2_05928 HuMAP2_06099 HuMAP2_06950 |