hu.MAP 2.0: Complex View
Human Protein Complex Map
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Complex: HuMAP2_02070
Confidence: Very High
Proteins| Genename | Protein Name | Links |
|---|---|---|
| BNIP1 | Vesicle transport protein SEC20 (BCL2/adenovirus E1B 19 kDa protein-interacting protein 1) (Transformation-related gene 8 protein) (TRG-8) | UniProt NCBI |
| STX18 | Syntaxin-18 (Cell growth-inhibiting gene 9 protein) | UniProt NCBI |
| SEC22B | Vesicle-trafficking protein SEC22b (ER-Golgi SNARE of 24 kDa) (ERS-24) (ERS24) (SEC22 vesicle-trafficking protein homolog B) (SEC22 vesicle-trafficking protein-like 1) | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| KEGG:04130 | 1.49158985786e-07 | 1.0 | SEC22B STX18 BNIP1 | SNARE interactions in vesicular transport |
| REAC:R-HSA-6811434 | 6.42384066445e-05 | 1.0 | SEC22B STX18 BNIP1 | COPI-dependent Golgi-to-ER retrograde traffic |
| REAC:R-HSA-8856688 | 0.000160847790881 | 1.0 | SEC22B STX18 BNIP1 | Golgi-to-ER retrograde transport |
| REAC:R-HSA-6811442 | 0.000564194667652 | 1.0 | SEC22B STX18 BNIP1 | Intra-Golgi and retrograde Golgi-to-ER traffic |
| GO:0031201 | 0.00137862598403 | 1.0 | SEC22B STX18 BNIP1 | SNARE complex |
| KEGG:04145 | 0.00402657539006 | 0.666666666667 | STX18 SEC22B | Phagosome |
| GO:0006890 | 0.0089701507538 | 1.0 | SEC22B STX18 BNIP1 | retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum |
| REAC:R-HSA-199991 | 0.0146202486223 | 1.0 | SEC22B STX18 BNIP1 | Membrane Trafficking |
| REAC:R-HSA-5653656 | 0.0171761243356 | 1.0 | SEC22B STX18 BNIP1 | Vesicle-mediated transport |
Edges
| Protein 1 | Protein 2 | Score | Precision | Evidence |
|---|---|---|---|---|
| BNIP1 | STX18 | 0.999 | 0.945 | hein_WMM bioplex (STX18) bioplex_WMM boldt youn_WMM gupta_WMM boldt_WMM |
| STX18 | SEC22B | 0.856 | 0.793 | bioplex (SEC22B,STX18) bioplex_WMM boldt youn_WMM gupta_WMM boldt_WMM |
| BNIP1 | SEC22B | 0.283 | 0.488 | bioplex (SEC22B) bioplex_WMM boldt youn_WMM gupta_WMM boldt_WMM |
Images
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Complex HuMAP2_02070 has an average edge precision of 0.742 which is ranked 1195 out of all 6965 complexes.
Related Complexes
| Genename | Complexes |
|---|---|
| BNIP1 | HuMAP2_00854 HuMAP2_02070 HuMAP2_02979 HuMAP2_04522 HuMAP2_06258 |
| STX18 | HuMAP2_00854 HuMAP2_02070 HuMAP2_02979 HuMAP2_04522 HuMAP2_06258 |
| SEC22B | HuMAP2_00854 HuMAP2_02070 HuMAP2_02979 HuMAP2_04522 HuMAP2_06376 |