hu.MAP 2.0: Complex View
Human Protein Complex Map
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Complex: HuMAP2_02081
Confidence: Extremely High
Proteins| Genename | Protein Name | Links |
|---|---|---|
| PPP4R3A | Serine/threonine-protein phosphatase 4 regulatory subunit 3A (SMEK homolog 1) | UniProt NCBI |
| PPP4C | Serine/threonine-protein phosphatase 4 catalytic subunit (PP4C) (Pp4) (EC 3.1.3.16) (Protein phosphatase X) (PP-X) | UniProt NCBI |
| PPP4R2 | Serine/threonine-protein phosphatase 4 regulatory subunit 2 | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| CORUM:1245 | 3.35600554376e-06 | 0.666666666667 | PPP4R2 PPP4C | Protein phosphatase 4 complex |
| CORUM:1750 | 2.01342304124e-05 | 0.666666666667 | PPP4R2 PPP4C | PPP4C-PPP4R2-Gemin3-Gemin4 complex |
| KEGG:04922 | 0.00203354700377 | 0.666666666667 | PPP4C PPP4R3A | Glucagon signaling pathway |
| REAC:R-HSA-5693607 | 0.03104119222 | 0.666666666667 | PPP4R2 PPP4C | Processing of DNA double-strand break ends |
Edges
| Protein 1 | Protein 2 | Score | Precision | Evidence |
|---|---|---|---|---|
| PPP4R2 | PPP4R3A | 1.0 | 0.949 | hein_WMM bioplex (PPP4R2,PPP4R3A) bioplex_WMM Guru boldt youn_WMM hein (PPP4R2,PPP4R3A) Malo gupta_WMM fraction boldt_WMM |
| PPP4C | PPP4R2 | 1.0 | 0.949 | hein_WMM bioplex (PPP4R2) bioplex_WMM Guru boldt youn_WMM hein (PPP4C,PPP4R2) gupta_WMM fraction boldt_WMM |
| PPP4C | PPP4R3A | 0.998 | 0.944 | hein_WMM bioplex (PPP4R3A) bioplex_WMM Guru boldt youn_WMM hein (PPP4C,PPP4R3A) gupta_WMM fraction boldt_WMM |
Images
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Complex HuMAP2_02081 has an average edge precision of 0.947 which is ranked 357 out of all 6965 complexes.
Related Complexes
| Genename | Complexes |
|---|---|
| PPP4R3A | HuMAP2_02081 HuMAP2_05448 HuMAP2_06695 HuMAP2_06754 |
| PPP4C | HuMAP2_02007 HuMAP2_02081 HuMAP2_04313 HuMAP2_05448 HuMAP2_06468 HuMAP2_06695 |
| PPP4R2 | HuMAP2_02081 HuMAP2_05448 HuMAP2_06468 HuMAP2_06695 |