hu.MAP 2.0: Complex View
Human Protein Complex Map
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Complex: HuMAP2_02091
Confidence: Medium High
Proteins| Genename | Protein Name | Links |
|---|---|---|
| VPS13B | Vacuolar protein sorting-associated protein 13B (Cohen syndrome protein 1) | UniProt NCBI |
| STUB1 | E3 ubiquitin-protein ligase CHIP (EC 2.3.2.27) (Antigen NY-CO-7) (CLL-associated antigen KW-8) (Carboxy terminus of Hsp70-interacting protein) (RING-type E3 ubiquitin transferase CHIP) (STIP1 homology and U box-containing protein 1) | UniProt NCBI |
| DNAJC7 | DnaJ homolog subfamily C member 7 (Tetratricopeptide repeat protein 2) (TPR repeat protein 2) | UniProt NCBI |
| KIAA0100 | Protein KIAA0100 (Antigen MLAA-22) (Breast cancer-overexpressed gene 1 protein) | UniProt NCBI |
| BAG2 | BAG family molecular chaperone regulator 2 (BAG-2) (Bcl-2-associated athanogene 2) | UniProt NCBI |
| EML5 | Echinoderm microtubule-associated protein-like 5 (EMAP-5) | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| REAC:R-HSA-3371453 | 0.0455991929544 | 0.333333333333 | DNAJC7 BAG2 | Regulation of HSF1-mediated heat shock response |
| CORUM:432 | 0.0499726005494 | 0.166666666667 | STUB1 | N-NOS-CHIP-HSP70-1 complex |
Edges
| Protein 1 | Protein 2 | Score | Precision | Evidence |
|---|---|---|---|---|
| DNAJC7 | STUB1 | 0.638 | 0.685 | hein_WMM bioplex_WMM boldt youn_WMM hein (DNAJC7) gupta_WMM boldt_WMM |
| DNAJC7 | BAG2 | 0.6 | 0.671 | hein_WMM bioplex (DNAJC7) bioplex_WMM boldt hein (BAG2,DNAJC7) gupta_WMM boldt_WMM |
| DNAJC7 | KIAA0100 | 0.25 | 0.474 | hein_WMM bioplex (DNAJC7) bioplex_WMM youn_WMM hein (DNAJC7) |
| DNAJC7 | VPS13B | 0.218 | 0.466 | hein_WMM bioplex (DNAJC7) bioplex_WMM hein (DNAJC7) |
| BAG2 | STUB1 | 0.194 | 0.447 | hein_WMM bioplex_WMM boldt hein (BAG2) gupta_WMM boldt_WMM |
| DNAJC7 | EML5 | 0.092 | 0.355 | bioplex (DNAJC7) bioplex_WMM |
| KIAA0100 | VPS13B | 0.009 | 0.108 | hein_WMM bioplex_WMM WMM_only |
| KIAA0100 | EML5 | 0.008 | 0.028 | bioplex_WMM WMM_only |
| VPS13B | EML5 | 0.007 | 0.01 | bioplex_WMM WMM_only |
| BAG2 | KIAA0100 | 0.007 | 0.01 | hein_WMM bioplex_WMM WMM_only |
| KIAA0100 | STUB1 | 0.007 | 0.012 | hein_WMM bioplex_WMM youn_WMM gupta_WMM WMM_only |
| STUB1 | VPS13B | 0.007 | 0.004 | hein_WMM bioplex_WMM WMM_only |
| BAG2 | EML5 | 0.007 | 0.006 | bioplex_WMM WMM_only |
| STUB1 | EML5 | 0.007 | 0.001 | WMM_only boldt_WMM |
| BAG2 | VPS13B | 0.007 | 0.004 | hein_WMM bioplex_WMM WMM_only |
Images
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Complex HuMAP2_02091 has an average edge precision of 0.219 which is ranked 5879 out of all 6965 complexes.
Related Complexes
| Genename | Complexes |
|---|---|
| VPS13B | HuMAP2_02091 HuMAP2_02851 |
| STUB1 | HuMAP2_02091 HuMAP2_02851 HuMAP2_04364 HuMAP2_05456 |
| DNAJC7 | HuMAP2_00457 HuMAP2_02047 HuMAP2_02091 HuMAP2_02851 |
| KIAA0100 | HuMAP2_02091 HuMAP2_02851 HuMAP2_04125 HuMAP2_04775 |
| BAG2 | HuMAP2_00457 HuMAP2_02091 HuMAP2_02851 HuMAP2_05029 |
| EML5 | HuMAP2_02091 HuMAP2_02851 |