hu.MAP 2.0: Complex View
Human Protein Complex Map
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Complex: HuMAP2_02100
Confidence: High
Proteins| Genename | Protein Name | Links |
|---|---|---|
| NIP7 | 60S ribosome subunit biogenesis protein NIP7 homolog (KD93) | UniProt NCBI |
| NOP2 | Probable 28S rRNA (cytosine(4447)-C(5))-methyltransferase (EC 2.1.1.-) (Nucleolar protein 1) (Nucleolar protein 2 homolog) (Proliferating-cell nucleolar antigen p120) (Proliferation-associated nucleolar protein p120) | UniProt NCBI |
| RRP15 | RRP15-like protein (Ribosomal RNA-processing protein 15) | UniProt NCBI |
| MRTO4 | mRNA turnover protein 4 homolog (Ribosome assembly factor MRTO4) | UniProt NCBI |
| GTPBP4 | Nucleolar GTP-binding protein 1 (Chronic renal failure gene protein) (GTP-binding protein NGB) | UniProt NCBI |
| DDX18 | ATP-dependent RNA helicase DDX18 (EC 3.6.4.13) (DEAD box protein 18) (Myc-regulated DEAD box protein) (MrDb) | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| GO:0042273 | 0.000216594058417 | 0.666666666667 | NOP2 MRTO4 NIP7 DDX18 | ribosomal large subunit biogenesis |
| GO:0030687 | 0.0032070828615 | 0.5 | MRTO4 RRP15 NIP7 | preribosome, large subunit precursor |
| GO:0042254 | 0.0442052130199 | 0.666666666667 | NOP2 MRTO4 NIP7 DDX18 | ribosome biogenesis |
Edges
| Protein 1 | Protein 2 | Score | Precision | Evidence |
|---|---|---|---|---|
| NIP7 | NOP2 | 1.0 | 0.949 | hein_WMM bioplex_WMM Guru youn_WMM fraction |
| MRTO4 | NOP2 | 0.999 | 0.949 | hein_WMM bioplex (MRTO4) bioplex_WMM youn_WMM gupta_WMM fraction treiber_WMM |
| GTPBP4 | NOP2 | 0.979 | 0.895 | hein_WMM bioplex_WMM Guru youn_WMM gupta_WMM fraction treiber_WMM |
| DDX18 | GTPBP4 | 0.978 | 0.893 | hein_WMM bioplex_WMM Guru youn_WMM gupta_WMM fraction treiber_WMM |
| RRP15 | NOP2 | 0.973 | 0.886 | hein_WMM bioplex_WMM Guru youn_WMM gupta_WMM fraction |
| RRP15 | NIP7 | 0.92 | 0.844 | hein_WMM bioplex_WMM Guru youn_WMM fraction |
| DDX18 | NOP2 | 0.821 | 0.773 | hein_WMM bioplex_WMM Guru youn_WMM gupta_WMM fraction treiber_WMM |
| MRTO4 | RRP15 | 0.682 | 0.709 | hein_WMM bioplex (MRTO4) bioplex_WMM Guru youn_WMM fraction treiber_WMM |
| MRTO4 | GTPBP4 | 0.522 | 0.634 | hein_WMM bioplex (MRTO4) bioplex_WMM youn_WMM gupta_WMM fraction |
| GTPBP4 | RRP15 | 0.432 | 0.578 | hein_WMM bioplex_WMM Guru youn_WMM gupta_WMM fraction treiber_WMM |
| MRTO4 | NIP7 | 0.322 | 0.512 | hein_WMM bioplex (MRTO4) bioplex_WMM youn_WMM treiber_WMM |
| DDX18 | NIP7 | 0.131 | 0.403 | hein_WMM bioplex_WMM Guru youn_WMM fraction |
| GTPBP4 | NIP7 | 0.052 | 0.303 | hein_WMM bioplex_WMM youn_WMM WMM_only |
| DDX18 | MRTO4 | 0.038 | 0.265 | hein_WMM bioplex (MRTO4) bioplex_WMM youn_WMM gupta_WMM treiber_WMM |
| DDX18 | RRP15 | 0.025 | 0.213 | hein_WMM bioplex_WMM Guru youn_WMM gupta_WMM fraction |
Images
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Complex HuMAP2_02100 has an average edge precision of 0.654 which is ranked 1633 out of all 6965 complexes.
Related Complexes