hu.MAP 2.0: Complex View
Human Protein Complex Map
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Complex: HuMAP2_02113
Confidence: Very High
Proteins| Genename | Protein Name | Links |
|---|---|---|
| PALM | Paralemmin-1 (Paralemmin) | UniProt NCBI |
| RABGGTB | Geranylgeranyl transferase type-2 subunit beta (EC 2.5.1.60) (Geranylgeranyl transferase type II subunit beta) (GGTase-II-beta) (Rab geranyl-geranyltransferase subunit beta) (Rab GG transferase beta) (Rab GGTase beta) (Rab geranylgeranyltransferase subunit beta) (Type II protein geranyl-geranyltransferase subunit beta) | UniProt NCBI |
| PGBD5 | PiggyBac transposable element-derived protein 5 (EC 3.1.-.-) (PiggyBac domain-related protein 5) (PiggyBac transposase 5) | UniProt NCBI |
| PTAR1 | Protein prenyltransferase alpha subunit repeat-containing protein 1 | UniProt NCBI |
| RABGGTA | Geranylgeranyl transferase type-2 subunit alpha (EC 2.5.1.60) (Geranylgeranyl transferase type II subunit alpha) (Rab geranyl-geranyltransferase subunit alpha) (Rab GG transferase alpha) (Rab GGTase alpha) (Rab geranylgeranyltransferase subunit alpha) | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| REAC:R-HSA-6803205 | 0.00105126658749 | 0.4 | RABGGTB RABGGTA | TP53 regulates transcription of several additional cell death genes whose specific roles in p53-dependent apoptosis remain uncertain |
| REAC:R-HSA-5633008 | 0.0104745816743 | 0.4 | RABGGTB RABGGTA | TP53 Regulates Transcription of Cell Death Genes |
| GO:0004663 | 0.0135228859698 | 0.4 | RABGGTB RABGGTA | Rab geranylgeranyltransferase activity |
| REAC:R-HSA-8873719 | 0.0253191001807 | 0.4 | RABGGTB RABGGTA | RAB geranylgeranylation |
| GO:0005968 | 0.0270421395626 | 0.4 | RABGGTB RABGGTA | Rab-protein geranylgeranyltransferase complex |
| GO:0004661 | 0.0450641792523 | 0.4 | RABGGTB RABGGTA | protein geranylgeranyltransferase activity |
Edges
| Protein 1 | Protein 2 | Score | Precision | Evidence |
|---|---|---|---|---|
| PTAR1 | RABGGTB | 1.0 | 0.949 | bioplex (RABGGTB) bioplex_WMM |
| RABGGTB | PGBD5 | 1.0 | 0.949 | bioplex (RABGGTB) bioplex_WMM |
| RABGGTB | RABGGTA | 1.0 | 0.949 | bioplex (RABGGTA,RABGGTB) bioplex_WMM Guru fraction |
| RABGGTB | PALM | 0.836 | 0.779 | bioplex (RABGGTB) bioplex_WMM |
| PTAR1 | PGBD5 | 0.009 | 0.108 | bioplex_WMM WMM_only |
| RABGGTA | PGBD5 | 0.008 | 0.067 | bioplex_WMM WMM_only |
| PTAR1 | RABGGTA | 0.008 | 0.015 | bioplex_WMM WMM_only |
| PALM | PGBD5 | 0.007 | 0.008 | bioplex_WMM WMM_only |
| PTAR1 | PALM | 0.007 | 0.004 | bioplex_WMM WMM_only |
| RABGGTA | PALM | 0.006 | 0.004 | bioplex_WMM WMM_only |
Images
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Complex HuMAP2_02113 has an average edge precision of 0.383 which is ranked 3490 out of all 6965 complexes.
Related Complexes
| Genename | Complexes |
|---|---|
| PALM | HuMAP2_02113 HuMAP2_06505 |
| RABGGTB | HuMAP2_00329 HuMAP2_02113 HuMAP2_06505 |
| PGBD5 | HuMAP2_02113 HuMAP2_06505 |
| PTAR1 | HuMAP2_00329 HuMAP2_00339 HuMAP2_02113 HuMAP2_02329 HuMAP2_02375 |
| RABGGTA | HuMAP2_01067 HuMAP2_02113 HuMAP2_03796 HuMAP2_07002 |