hu.MAP 2.0: Complex View
Human Protein Complex Map
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Complex: HuMAP2_02120
Confidence: Medium
Proteins| Genename | Protein Name | Links |
|---|---|---|
| ZNF106 | Zinc finger protein 106 (Zfp-106) (Zinc finger protein 474) | UniProt NCBI |
| KNOP1 | Lysine-rich nucleolar protein 1 (Protein FAM191A) (Testis-specific gene 118 protein) | UniProt NCBI |
| UTP18 | U3 small nucleolar RNA-associated protein 18 homolog (WD repeat-containing protein 50) | UniProt NCBI |
| DDX56 | Probable ATP-dependent RNA helicase DDX56 (EC 3.6.4.13) (ATP-dependent 61 kDa nucleolar RNA helicase) (DEAD box protein 21) (DEAD box protein 56) | UniProt NCBI |
| UTP3 | Something about silencing protein 10 (Charged amino acid-rich leucine zipper 1) (CRL1) (Disrupter of silencing SAS10) (UTP3 homolog) | UniProt NCBI |
| BMS1 | Ribosome biogenesis protein BMS1 homolog (Ribosome assembly protein BMS1 homolog) | UniProt NCBI |
| BOP1 | Ribosome biogenesis protein BOP1 (Block of proliferation 1 protein) | UniProt NCBI |
| DDX10 | Probable ATP-dependent RNA helicase DDX10 (EC 3.6.4.13) (DEAD box protein 10) | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| REAC:R-HSA-6791226 | 0.00025210536412 | 0.5 | BMS1 BOP1 UTP3 UTP18 | Major pathway of rRNA processing in the nucleolus and cytosol |
| REAC:R-HSA-8868773 | 0.000312480655384 | 0.5 | BMS1 BOP1 UTP3 UTP18 | rRNA processing in the nucleus and cytosol |
| GO:0003723 | 0.000352719185521 | 1.0 | DDX56 BOP1 ZNF106 UTP3 UTP18 DDX10 BMS1 KNOP1 | RNA binding |
| REAC:R-HSA-72312 | 0.000383017777676 | 0.5 | BMS1 BOP1 UTP3 UTP18 | rRNA processing |
| GO:0006364 | 0.000543241541308 | 0.625 | BMS1 BOP1 DDX10 UTP3 UTP18 | rRNA processing |
| REAC:R-HSA-6790901 | 0.000608348414674 | 0.375 | BMS1 UTP3 UTP18 | rRNA modification in the nucleus and cytosol |
| GO:0016072 | 0.000701002918108 | 0.625 | BMS1 BOP1 DDX10 UTP3 UTP18 | rRNA metabolic process |
| GO:0030684 | 0.00183129501431 | 0.5 | BMS1 BOP1 UTP3 UTP18 | preribosome |
| GO:0042254 | 0.00252497401082 | 0.625 | BMS1 BOP1 DDX10 UTP3 UTP18 | ribosome biogenesis |
| GO:0034470 | 0.0108967875586 | 0.625 | BMS1 BOP1 DDX10 UTP3 UTP18 | ncRNA processing |
| GO:0030686 | 0.0184623087477 | 0.375 | BMS1 BOP1 UTP18 | 90S preribosome |
| GO:0022613 | 0.0242514907763 | 0.625 | BMS1 BOP1 DDX10 UTP3 UTP18 | ribonucleoprotein complex biogenesis |
| GO:0003676 | 0.0339112472963 | 1.0 | DDX56 BOP1 ZNF106 UTP3 UTP18 DDX10 BMS1 KNOP1 | nucleic acid binding |
| KEGG:03008 | 0.0348056719149 | 0.25 | BMS1 UTP18 | Ribosome biogenesis in eukaryotes |
| GO:0034660 | 0.0361459175116 | 0.625 | BMS1 BOP1 DDX10 UTP3 UTP18 | ncRNA metabolic process |
| REAC:R-HSA-8953854 | 0.039220545455 | 0.5 | BMS1 BOP1 UTP3 UTP18 | Metabolism of RNA |
Edges
| Protein 1 | Protein 2 | Score | Precision | Evidence |
|---|---|---|---|---|
| ZNF106 | KNOP1 | 0.766 | 0.75 | bioplex (KNOP1) bioplex_WMM youn_WMM gupta_WMM |
| KNOP1 | DDX10 | 0.062 | 0.344 | bioplex (KNOP1) bioplex_WMM youn_WMM gupta_WMM treiber_WMM |
| DDX56 | DDX10 | 0.053 | 0.298 | bioplex_WMM gupta_WMM fraction treiber_WMM |
| DDX56 | KNOP1 | 0.033 | 0.251 | bioplex (KNOP1) bioplex_WMM gupta_WMM treiber_WMM |
| UTP18 | KNOP1 | 0.032 | 0.24 | bioplex (KNOP1) bioplex_WMM youn_WMM treiber_WMM |
| KNOP1 | BMS1 | 0.03 | 0.235 | bioplex (KNOP1) bioplex_WMM youn_WMM gupta_WMM treiber_WMM |
| BOP1 | KNOP1 | 0.029 | 0.23 | bioplex (KNOP1) bioplex_WMM youn_WMM gupta_WMM treiber_WMM |
| KNOP1 | UTP3 | 0.028 | 0.232 | bioplex_WMM youn_WMM gupta_WMM WMM_only treiber_WMM |
| BMS1 | DDX10 | 0.022 | 0.195 | bioplex_WMM youn_WMM gupta_WMM WMM_only treiber_WMM |
| UTP3 | DDX10 | 0.018 | 0.182 | bioplex_WMM youn_WMM gupta_WMM WMM_only treiber_WMM |
| DDX56 | BMS1 | 0.017 | 0.175 | bioplex_WMM gupta_WMM WMM_only treiber_WMM |
| UTP3 | BMS1 | 0.017 | 0.164 | bioplex_WMM youn_WMM gupta_WMM WMM_only treiber_WMM |
| UTP18 | BMS1 | 0.014 | 0.143 | bioplex_WMM youn_WMM WMM_only treiber_WMM |
| UTP18 | UTP3 | 0.011 | 0.145 | bioplex_WMM youn_WMM WMM_only treiber_WMM |
| DDX56 | UTP3 | 0.01 | 0.104 | bioplex_WMM gupta_WMM WMM_only treiber_WMM |
| BOP1 | UTP3 | 0.009 | 0.108 | bioplex_WMM youn_WMM gupta_WMM WMM_only treiber_WMM |
| BOP1 | DDX10 | 0.009 | 0.099 | bioplex_WMM youn_WMM gupta_WMM WMM_only treiber_WMM |
| BOP1 | UTP18 | 0.008 | 0.067 | bioplex_WMM youn_WMM WMM_only treiber_WMM |
| UTP18 | DDX56 | 0.008 | 0.05 | bioplex_WMM WMM_only treiber_WMM |
| ZNF106 | UTP3 | 0.008 | 0.024 | youn_WMM gupta_WMM WMM_only |
| UTP18 | DDX10 | 0.008 | 0.025 | bioplex_WMM youn_WMM WMM_only treiber_WMM |
| BOP1 | ZNF106 | 0.008 | 0.013 | bioplex_WMM youn_WMM gupta_WMM WMM_only |
| ZNF106 | BMS1 | 0.008 | 0.01 | bioplex_WMM youn_WMM gupta_WMM WMM_only treiber_WMM |
| ZNF106 | DDX10 | 0.007 | 0.008 | bioplex_WMM youn_WMM gupta_WMM WMM_only |
| BOP1 | BMS1 | 0.007 | 0.009 | bioplex_WMM youn_WMM gupta_WMM WMM_only treiber_WMM |
| UTP18 | ZNF106 | 0.007 | 0.011 | bioplex_WMM youn_WMM WMM_only |
| BOP1 | DDX56 | 0.007 | 0.007 | bioplex_WMM gupta_WMM WMM_only treiber_WMM |
| DDX56 | ZNF106 | 0.007 | 0.003 | bioplex_WMM gupta_WMM WMM_only |
Images
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Complex HuMAP2_02120 has an average edge precision of 0.147 which is ranked 6719 out of all 6965 complexes.
Related Complexes
| Genename | Complexes |
|---|---|
| ZNF106 | HuMAP2_02120 HuMAP2_03219 HuMAP2_03313 HuMAP2_03961 HuMAP2_05299 |
| KNOP1 | HuMAP2_02120 HuMAP2_03313 HuMAP2_03961 |
| UTP18 | HuMAP2_01223 HuMAP2_02120 |
| DDX56 | HuMAP2_01863 HuMAP2_02120 HuMAP2_04970 HuMAP2_06147 |
| UTP3 | HuMAP2_02120 |
| BMS1 | HuMAP2_02120 HuMAP2_02309 HuMAP2_06257 HuMAP2_06281 HuMAP2_06905 |
| BOP1 | HuMAP2_00325 HuMAP2_00379 HuMAP2_01344 HuMAP2_01531 HuMAP2_02120 HuMAP2_02420 HuMAP2_04175 HuMAP2_04828 |
| DDX10 | HuMAP2_02120 HuMAP2_02205 HuMAP2_03961 HuMAP2_06257 |