hu.MAP 2.0: Complex View
Human Protein Complex Map
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Complex: HuMAP2_02139
Confidence: Very High
Proteins| Genename | Protein Name | Links |
|---|---|---|
| DDX20 | Probable ATP-dependent RNA helicase DDX20 (EC 3.6.4.13) (Component of gems 3) (DEAD box protein 20) (DEAD box protein DP 103) (Gemin-3) | UniProt NCBI |
| GEMIN4 | Gem-associated protein 4 (Gemin-4) (Component of gems 4) (p97) | UniProt NCBI |
| GEMIN5 | Gem-associated protein 5 (Gemin5) | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| CORUM:3296 | 2.25356268047e-10 | 1.0 | GEMIN4 DDX20 GEMIN5 | SMN complex (GEMIN5,4,3), SMN-independent intermediate |
| CORUM:3284 | 9.0142507219e-10 | 1.0 | GEMIN4 DDX20 GEMIN5 | SMN complex (GEMIN2, GEMIN3, GEMIN4, GEMIN5, SMN) |
| CORUM:1752 | 4.50712536095e-09 | 1.0 | GEMIN4 DDX20 GEMIN5 | SMN complex |
| CORUM:1751 | 1.8929926516e-08 | 1.0 | GEMIN4 DDX20 GEMIN5 | SMN complex |
| CORUM:1745 | 1.02537101962e-07 | 1.0 | GEMIN4 DDX20 GEMIN5 | SMN complex |
| CORUM:1143 | 1.02537101962e-07 | 1.0 | GEMIN4 DDX20 GEMIN5 | SMN complex |
| REAC:R-HSA-194441 | 8.81209945571e-06 | 1.0 | GEMIN4 DDX20 GEMIN5 | Metabolism of non-coding RNA |
| REAC:R-HSA-191859 | 8.81209945571e-06 | 1.0 | GEMIN4 DDX20 GEMIN5 | snRNP Assembly |
| GO:0032797 | 1.49850650438e-05 | 1.0 | GEMIN4 DDX20 GEMIN5 | SMN complex |
| KEGG:03013 | 1.76006400333e-05 | 1.0 | GEMIN4 DDX20 GEMIN5 | RNA transport |
| CORUM:1750 | 2.01342304124e-05 | 0.666666666667 | GEMIN4 DDX20 | PPP4C-PPP4R2-Gemin3-Gemin4 complex |
| CORUM:824 | 2.01342304124e-05 | 0.666666666667 | GEMIN4 DDX20 | Anti-SMN protein complex |
| CORUM:832 | 5.03310689057e-05 | 0.666666666667 | GEMIN4 DDX20 | Anti-Sm protein complex |
| GO:0034719 | 6.17566316957e-05 | 1.0 | GEMIN4 DDX20 GEMIN5 | SMN-Sm protein complex |
| CORUM:1749 | 0.000150966163965 | 0.666666666667 | GEMIN4 DDX20 | SMN-PolII-RHA complex |
| GO:0000387 | 0.000766145507331 | 1.0 | GEMIN4 DDX20 GEMIN5 | spliceosomal snRNP assembly |
| GO:0120114 | 0.00588722337212 | 1.0 | GEMIN4 DDX20 GEMIN5 | Sm-like protein family complex |
| REAC:R-HSA-8953854 | 0.0206735000409 | 1.0 | GEMIN4 DDX20 GEMIN5 | Metabolism of RNA |
| GO:0051170 | 0.0248678516681 | 1.0 | GEMIN4 DDX20 GEMIN5 | import into nucleus |
| CORUM:3298 | 0.0499776345577 | 0.333333333333 | GEMIN5 | SMN complex (GEMIN2,5, SMN) |
Edges
| Protein 1 | Protein 2 | Score | Precision | Evidence |
|---|---|---|---|---|
| DDX20 | GEMIN5 | 0.998 | 0.936 | hein_WMM youn (DDX20) bioplex (DDX20) bioplex_WMM youn_WMM hein (GEMIN5) gupta_WMM treiber_WMM |
| GEMIN4 | DDX20 | 0.997 | 0.93 | hein_WMM youn (DDX20) bioplex (DDX20) bioplex_WMM youn_WMM treiber_WMM |
| GEMIN4 | GEMIN5 | 0.014 | 0.138 | hein_WMM bioplex_WMM youn_WMM hein (GEMIN5) treiber_WMM |
Images
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Complex HuMAP2_02139 has an average edge precision of 0.668 which is ranked 1529 out of all 6965 complexes.
Related Complexes
| Genename | Complexes |
|---|---|
| DDX20 | HuMAP2_00197 HuMAP2_01368 HuMAP2_01989 HuMAP2_02139 HuMAP2_02424 HuMAP2_03256 HuMAP2_05111 |
| GEMIN4 | HuMAP2_00197 HuMAP2_01368 HuMAP2_01989 HuMAP2_02139 HuMAP2_02424 HuMAP2_03256 HuMAP2_05111 |
| GEMIN5 | HuMAP2_01368 HuMAP2_02139 HuMAP2_02196 HuMAP2_02424 HuMAP2_06013 |