hu.MAP 2.0: Complex View
Human Protein Complex Map
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Complex: HuMAP2_02149
Confidence: Very High
Proteins| Genename | Protein Name | Links |
|---|---|---|
| PPP1R13B | Apoptosis-stimulating of p53 protein 1 (Protein phosphatase 1 regulatory subunit 13B) | UniProt NCBI |
| PARD3 | Partitioning defective 3 homolog (PAR-3) (PARD-3) (Atypical PKC isotype-specific-interacting protein) (ASIP) (CTCL tumor antigen se2-5) (PAR3-alpha) | UniProt NCBI |
| PARD6B | Partitioning defective 6 homolog beta (PAR-6 beta) (PAR-6B) | UniProt NCBI |
| RASSF8 | Ras association domain-containing protein 8 (Carcinoma-associated protein HOJ-1) | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| CORUM:956 | 1.50819606993e-05 | 0.5 | PARD6B PARD3 | PAR-3-PAR-6B-PRKCI complex |
| REAC:R-HSA-420029 | 0.00105460323216 | 0.5 | PARD6B PARD3 | Tight junction interactions |
| REAC:R-HSA-421270 | 0.00947680746611 | 0.5 | PARD6B PARD3 | Cell-cell junction organization |
| KEGG:04390 | 0.0198080875546 | 0.5 | PARD6B PARD3 | Hippo signaling pathway |
| KEGG:04530 | 0.0206513420529 | 0.5 | PARD6B PARD3 | Tight junction |
| REAC:R-HSA-446728 | 0.0248339118539 | 0.5 | PARD6B PARD3 | Cell junction organization |
| KEGG:04360 | 0.0267154932054 | 0.5 | PARD6B PARD3 | Axon guidance |
| KEGG:04015 | 0.0293559966201 | 0.5 | PARD6B PARD3 | Rap1 signaling pathway |
| MIRNA:hsa-miR-629-5p | 0.0302525005955 | 0.5 | RASSF8 PARD3 | hsa-miR-629-5p |
| CORUM:644 | 0.0499140284799 | 0.25 | PPP1R13B | ASPP1-SAM68 complex |
| CORUM:5558 | 0.0499140284799 | 0.25 | PARD6B | PAR6-CDC42 complex |
Edges
| Protein 1 | Protein 2 | Score | Precision | Evidence |
|---|---|---|---|---|
| PARD6B | PARD3 | 1.0 | 0.949 | hein_WMM bioplex (PARD6B) bioplex_WMM hein (PARD6B) |
| RASSF8 | PARD3 | 1.0 | 0.949 | hein_WMM bioplex (RASSF8) bioplex_WMM boldt youn_WMM hein (RASSF8) gupta_WMM boldt_WMM |
| RASSF8 | PPP1R13B | 0.983 | 0.899 | bioplex (RASSF8) bioplex_WMM boldt youn_WMM gupta_WMM boldt_WMM |
| PARD6B | RASSF8 | 0.76 | 0.75 | hein_WMM bioplex (PARD6B) bioplex_WMM hein (PARD6B) |
| PPP1R13B | PARD3 | 0.009 | 0.095 | bioplex_WMM youn_WMM gupta_WMM WMM_only |
Images
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Complex HuMAP2_02149 has an average edge precision of 0.728 which is ranked 1276 out of all 6965 complexes.
Related Complexes
| Genename | Complexes |
|---|---|
| PPP1R13B | HuMAP2_00604 HuMAP2_02149 HuMAP2_02376 HuMAP2_05899 |
| PARD3 | HuMAP2_01053 HuMAP2_01276 HuMAP2_01528 HuMAP2_02149 HuMAP2_02503 HuMAP2_05511 |
| PARD6B | HuMAP2_00450 HuMAP2_01276 HuMAP2_01528 HuMAP2_02149 HuMAP2_02503 HuMAP2_05511 |
| RASSF8 | HuMAP2_00604 HuMAP2_01053 HuMAP2_01276 HuMAP2_02149 HuMAP2_02376 HuMAP2_02503 HuMAP2_04109 |