hu.MAP 2.0: Complex View
Human Protein Complex Map
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Complex: HuMAP2_02155
Confidence: Medium
Proteins| Genename | Protein Name | Links |
|---|---|---|
| NOCT | Nocturnin (EC 3.1.13.4) (Carbon catabolite repression 4-like protein) (Circadian deadenylase NOC) | UniProt NCBI |
| TMEM8A | Post-GPI attachment to proteins factor 6 (EC 3.1.1.4) (GPI processing phospholipase A2) (GPI-PLA2) (Protein M83) (Transmembrane protein 6) (Transmembrane protein 8) (Transmembrane protein 8A) | UniProt NCBI |
| ATP1A4 | Sodium/potassium-transporting ATPase subunit alpha-4 (Na(+)/K(+) ATPase alpha-4 subunit) (EC 7.2.2.13) (Sodium pump subunit alpha-4) | UniProt NCBI |
| CHRM3 | Muscarinic acetylcholine receptor M3 | UniProt NCBI |
| ATP1B4 | Protein ATP1B4 (X,K-ATPase subunit beta-m) (X/potassium-transporting ATPase subunit beta-m) | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| KEGG:04971 | 3.09475559386e-05 | 0.6 | ATP1B4 CHRM3 ATP1A4 | Gastric acid secretion |
| KEGG:04911 | 5.12270645743e-05 | 0.6 | ATP1B4 CHRM3 ATP1A4 | Insulin secretion |
| KEGG:04970 | 5.56685456996e-05 | 0.6 | ATP1B4 CHRM3 ATP1A4 | Salivary secretion |
| KEGG:04972 | 7.32179527008e-05 | 0.6 | ATP1B4 CHRM3 ATP1A4 | Pancreatic secretion |
| KEGG:04964 | 0.00081380532431 | 0.4 | ATP1A4 ATP1B4 | Proximal tubule bicarbonate reclamation |
| KEGG:04960 | 0.00198873883948 | 0.4 | ATP1A4 ATP1B4 | Aldosterone-regulated sodium reabsorption |
| KEGG:04973 | 0.00333191455164 | 0.4 | ATP1A4 ATP1B4 | Carbohydrate digestion and absorption |
| KEGG:04978 | 0.00441762805526 | 0.4 | ATP1A4 ATP1B4 | Mineral absorption |
| KEGG:04961 | 0.00522578105965 | 0.4 | ATP1A4 ATP1B4 | Endocrine and other factor-regulated calcium reabsorption |
| KEGG:04976 | 0.00656425237639 | 0.4 | ATP1A4 ATP1B4 | Bile secretion |
| KEGG:04918 | 0.00969431019543 | 0.4 | ATP1A4 ATP1B4 | Thyroid hormone synthesis |
| KEGG:04974 | 0.0117982317972 | 0.4 | ATP1A4 ATP1B4 | Protein digestion and absorption |
| KEGG:04260 | 0.0121154716042 | 0.4 | ATP1A4 ATP1B4 | Cardiac muscle contraction |
| KEGG:04925 | 0.0162467151192 | 0.4 | ATP1A4 ATP1B4 | Aldosterone synthesis and secretion |
| WP:WP536 | 0.0234679122485 | 0.4 | CHRM3 ATP1A4 | Calcium Regulation in the Cardiac Cell |
| KEGG:04919 | 0.0267668372004 | 0.4 | ATP1A4 ATP1B4 | Thyroid hormone signaling pathway |
| KEGG:04261 | 0.0348468299156 | 0.4 | ATP1A4 ATP1B4 | Adrenergic signaling in cardiomyocytes |
| KEGG:04022 | 0.0415917953149 | 0.4 | ATP1A4 ATP1B4 | cGMP-PKG signaling pathway |
Edges
| Protein 1 | Protein 2 | Score | Precision | Evidence |
|---|---|---|---|---|
| CHRM3 | ATP1A4 | 0.366 | 0.543 | bioplex (CHRM3) bioplex_WMM |
| ATP1B4 | ATP1A4 | 0.349 | 0.536 | bioplex (ATP1B4) bioplex_WMM |
| CHRM3 | NOCT | 0.025 | 0.211 | bioplex (CHRM3) bioplex_WMM |
| ATP1B4 | TMEM8A | 0.021 | 0.195 | bioplex (ATP1B4) bioplex_WMM |
| ATP1A4 | TMEM8A | 0.008 | 0.068 | bioplex_WMM WMM_only |
| ATP1A4 | NOCT | 0.007 | 0.004 | bioplex_WMM WMM_only |
Images
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Complex HuMAP2_02155 has an average edge precision of 0.26 which is ranked 5235 out of all 6965 complexes.
Related Complexes
| Genename | Complexes |
|---|---|
| NOCT | HuMAP2_02155 HuMAP2_04472 HuMAP2_04770 |
| TMEM8A | HuMAP2_02155 HuMAP2_04770 |
| ATP1A4 | HuMAP2_00711 HuMAP2_02155 HuMAP2_02677 HuMAP2_03681 HuMAP2_04770 HuMAP2_06535 HuMAP2_06635 |
| CHRM3 | HuMAP2_00711 HuMAP2_02155 HuMAP2_04472 HuMAP2_04770 |
| ATP1B4 | HuMAP2_00711 HuMAP2_02155 HuMAP2_04770 HuMAP2_06535 |