hu.MAP 2.0: Complex View
Human Protein Complex Map
Search for a protein
Complex: HuMAP2_02161
Confidence: Medium High
Proteins| Genename | Protein Name | Links |
|---|---|---|
| ATP5F1C | ATP synthase subunit gamma, mitochondrial (ATP synthase F1 subunit gamma) (F-ATPase gamma subunit) | UniProt NCBI |
| ATP5PO | ATP synthase subunit O, mitochondrial (ATP synthase peripheral stalk subunit OSCP) (Oligomycin sensitivity conferral protein) (OSCP) | UniProt NCBI |
| ATP5MG | ATP synthase subunit g, mitochondrial (ATPase subunit g) (ATP synthase membrane subunit g) | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| CORUM:563 | 1.26199510107e-07 | 1.0 | ATP5PO ATP5MG ATP5F1C | F1F0-ATP synthase, mitochondrial |
| REAC:R-HSA-163210 | 3.66871079381e-07 | 1.0 | ATP5PO ATP5MG ATP5F1C | Formation of ATP by chemiosmotic coupling |
| REAC:R-HSA-8949613 | 1.82536345868e-06 | 1.0 | ATP5PO ATP5MG ATP5F1C | Cristae formation |
| KEGG:00190 | 8.02679835688e-06 | 1.0 | ATP5PO ATP5MG ATP5F1C | Oxidative phosphorylation |
| WP:WP111 | 8.35827186966e-06 | 1.0 | ATP5PO ATP5MG ATP5F1C | Electron Transport Chain (OXPHOS system in mitochondria) |
| KEGG:04714 | 4.51020686166e-05 | 1.0 | ATP5PO ATP5MG ATP5F1C | Thermogenesis |
| REAC:R-HSA-1592230 | 4.93369666261e-05 | 1.0 | ATP5PO ATP5MG ATP5F1C | Mitochondrial biogenesis |
| GO:0005753 | 0.000103533176666 | 1.0 | ATP5PO ATP5MG ATP5F1C | mitochondrial proton-transporting ATP synthase complex |
| GO:0045259 | 0.000103533176666 | 1.0 | ATP5PO ATP5MG ATP5F1C | proton-transporting ATP synthase complex |
| REAC:R-HSA-163200 | 0.000113954833063 | 1.0 | ATP5PO ATP5MG ATP5F1C | Respiratory electron transport, ATP synthesis by chemiosmotic coupling, and heat production by uncoupling proteins. |
| GO:0042776 | 0.000160839698137 | 1.0 | ATP5PO ATP5MG ATP5F1C | mitochondrial ATP synthesis coupled proton transport |
| GO:0015985 | 0.000183816797871 | 1.0 | ATP5PO ATP5MG ATP5F1C | energy coupled proton transport, down electrochemical gradient |
| GO:0015986 | 0.000183816797871 | 1.0 | ATP5PO ATP5MG ATP5F1C | ATP synthesis coupled proton transport |
| REAC:R-HSA-1428517 | 0.000330512177188 | 1.0 | ATP5PO ATP5MG ATP5F1C | The citric acid (TCA) cycle and respiratory electron transport |
| GO:0042407 | 0.000368723418654 | 1.0 | ATP5PO ATP5MG ATP5F1C | cristae formation |
| GO:0006754 | 0.000648444632805 | 1.0 | ATP5PO ATP5MG ATP5F1C | ATP biosynthetic process |
| GO:0009206 | 0.000766145507331 | 1.0 | ATP5PO ATP5MG ATP5F1C | purine ribonucleoside triphosphate biosynthetic process |
| GO:0009145 | 0.000766145507331 | 1.0 | ATP5PO ATP5MG ATP5F1C | purine nucleoside triphosphate biosynthetic process |
| GO:0016469 | 0.000968126020406 | 1.0 | ATP5PO ATP5MG ATP5F1C | proton-transporting two-sector ATPase complex |
| GO:0009201 | 0.000968126020406 | 1.0 | ATP5PO ATP5MG ATP5F1C | ribonucleoside triphosphate biosynthetic process |
| GO:0007007 | 0.00104259725275 | 1.0 | ATP5PO ATP5MG ATP5F1C | inner mitochondrial membrane organization |
| WP:WP623 | 0.00142103052979 | 0.666666666667 | ATP5PO ATP5MG | Oxidative phosphorylation |
| GO:0009205 | 0.0015707980909 | 1.0 | ATP5PO ATP5MG ATP5F1C | purine ribonucleoside triphosphate metabolic process |
| REAC:R-HSA-1852241 | 0.00160990717739 | 1.0 | ATP5PO ATP5MG ATP5F1C | Organelle biogenesis and maintenance |
| GO:0009142 | 0.00167324144465 | 1.0 | ATP5PO ATP5MG ATP5F1C | nucleoside triphosphate biosynthetic process |
| GO:0009199 | 0.00189129684568 | 1.0 | ATP5PO ATP5MG ATP5F1C | ribonucleoside triphosphate metabolic process |
| GO:0009144 | 0.00200709053011 | 1.0 | ATP5PO ATP5MG ATP5F1C | purine nucleoside triphosphate metabolic process |
| KEGG:05012 | 0.00350714576187 | 0.666666666667 | ATP5PO ATP5F1C | Parkinson disease |
| GO:1902600 | 0.00455146375597 | 1.0 | ATP5PO ATP5MG ATP5F1C | proton transmembrane transport |
| GO:0009141 | 0.00475834847216 | 1.0 | ATP5PO ATP5MG ATP5F1C | nucleoside triphosphate metabolic process |
| KEGG:05010 | 0.00524007678336 | 0.666666666667 | ATP5PO ATP5F1C | Alzheimer disease |
| KEGG:05016 | 0.00684298122566 | 0.666666666667 | ATP5PO ATP5F1C | Huntington disease |
| GO:1990542 | 0.0103137207675 | 1.0 | ATP5PO ATP5MG ATP5F1C | mitochondrial transmembrane transport |
| KEGG:01100 | 0.0105851300972 | 1.0 | ATP5PO ATP5MG ATP5F1C | Metabolic pathways |
| GO:0007006 | 0.0190659069388 | 1.0 | ATP5PO ATP5MG ATP5F1C | mitochondrial membrane organization |
| GO:0098800 | 0.0218385980648 | 1.0 | ATP5PO ATP5MG ATP5F1C | inner mitochondrial membrane protein complex |
| GO:0006119 | 0.0248678516681 | 1.0 | ATP5PO ATP5MG ATP5F1C | oxidative phosphorylation |
| GO:0009152 | 0.0268132763851 | 1.0 | ATP5PO ATP5MG ATP5F1C | purine ribonucleotide biosynthetic process |
| GO:0009260 | 0.0317414555944 | 1.0 | ATP5PO ATP5MG ATP5F1C | ribonucleotide biosynthetic process |
| GO:0006164 | 0.0364177948924 | 1.0 | ATP5PO ATP5MG ATP5F1C | purine nucleotide biosynthetic process |
| GO:0046390 | 0.0364177948924 | 1.0 | ATP5PO ATP5MG ATP5F1C | ribose phosphate biosynthetic process |
| GO:0072522 | 0.0461431021058 | 1.0 | ATP5PO ATP5MG ATP5F1C | purine-containing compound biosynthetic process |
Edges
| Protein 1 | Protein 2 | Score | Precision | Evidence |
|---|---|---|---|---|
| ATP5F1C | ATP5PO | 1.0 | 0.949 | hein_WMM bioplex (ATP5F1C) bioplex_WMM Guru boldt gupta_WMM fraction boldt_WMM treiber_WMM |
| ATP5MG | ATP5PO | 1.0 | 0.949 | bioplex_WMM Guru boldt youn_WMM gupta_WMM fraction boldt_WMM |
| ATP5F1C | ATP5MG | 0.972 | 0.885 | bioplex (ATP5F1C) bioplex_WMM Guru boldt gupta_WMM fraction boldt_WMM |
Images
Click to enlarge
Complex HuMAP2_02161 has an average edge precision of 0.928 which is ranked 442 out of all 6965 complexes.
Related Complexes