hu.MAP 2.0: Complex View
Human Protein Complex Map
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Complex: HuMAP2_02173
Confidence: Very High
Proteins| Genename | Protein Name | Links |
|---|---|---|
| DYRK1A | Dual specificity tyrosine-phosphorylation-regulated kinase 1A (EC 2.7.12.1) (Dual specificity YAK1-related kinase) (HP86) (Protein kinase minibrain homolog) (MNBH) (hMNB) | UniProt NCBI |
| LZTS2 | Leucine zipper putative tumor suppressor 2 (hLZTS2) (Protein LAPSER1) | UniProt NCBI |
| SIPA1L3 | Signal-induced proliferation-associated 1-like protein 3 (SIPA1-like protein 3) (SPA-1-like protein 3) | UniProt NCBI |
| LZTS1 | Leucine zipper putative tumor suppressor 1 (F37/esophageal cancer-related gene-coding leucine-zipper motif) (Fez1) | UniProt NCBI |
| SIPA1L2 | Signal-induced proliferation-associated 1-like protein 2 (SIPA1-like protein 2) | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|
Edges
| Protein 1 | Protein 2 | Score | Precision | Evidence |
|---|---|---|---|---|
| SIPA1L2 | LZTS2 | 0.999 | 0.948 | youn (LZTS2) bioplex (LZTS2) bioplex_WMM youn_WMM gupta_WMM |
| LZTS2 | LZTS1 | 0.989 | 0.902 | youn (LZTS2) bioplex (LZTS2) bioplex_WMM youn_WMM |
| LZTS2 | SIPA1L3 | 0.972 | 0.885 | hein_WMM youn (LZTS2) bioplex (LZTS2) bioplex_WMM youn_WMM gupta_WMM |
| LZTS2 | DYRK1A | 0.87 | 0.803 | youn (LZTS2) bioplex (LZTS2) bioplex_WMM youn_WMM gupta_WMM boldt_WMM |
| SIPA1L2 | SIPA1L3 | 0.009 | 0.09 | bioplex_WMM youn_WMM gupta_WMM WMM_only boldt_WMM |
| SIPA1L2 | DYRK1A | 0.009 | 0.098 | bioplex_WMM boldt youn_WMM gupta_WMM boldt_WMM |
| LZTS1 | SIPA1L3 | 0.008 | 0.094 | bioplex_WMM youn_WMM WMM_only |
| SIPA1L2 | LZTS1 | 0.008 | 0.089 | bioplex_WMM youn_WMM WMM_only |
| DYRK1A | LZTS1 | 0.008 | 0.084 | bioplex_WMM youn_WMM WMM_only |
| DYRK1A | SIPA1L3 | 0.008 | 0.08 | bioplex_WMM youn_WMM gupta_WMM WMM_only boldt_WMM |
Images
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Complex HuMAP2_02173 has an average edge precision of 0.407 which is ranked 3234 out of all 6965 complexes.
Related Complexes
| Genename | Complexes |
|---|---|
| DYRK1A | HuMAP2_02173 HuMAP2_03011 HuMAP2_05742 |
| LZTS2 | HuMAP2_00618 HuMAP2_02173 HuMAP2_03011 HuMAP2_03772 |
| SIPA1L3 | HuMAP2_02173 HuMAP2_03772 HuMAP2_04789 HuMAP2_05933 |
| LZTS1 | HuMAP2_02173 HuMAP2_02337 HuMAP2_03011 HuMAP2_03772 |
| SIPA1L2 | HuMAP2_00035 HuMAP2_00618 HuMAP2_02173 HuMAP2_02612 HuMAP2_03011 HuMAP2_03772 |