hu.MAP 2.0: Complex View
Human Protein Complex Map
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Complex: HuMAP2_02179
Confidence: Medium High
Proteins| Genename | Protein Name | Links |
|---|---|---|
| WNK1 | Serine/threonine-protein kinase WNK1 (EC 2.7.11.1) (Erythrocyte 65 kDa protein) (p65) (Kinase deficient protein) (Protein kinase lysine-deficient 1) (Protein kinase with no lysine 1) (hWNK1) | UniProt NCBI |
| LCP1 | Plastin-2 (L-plastin) (LC64P) (Lymphocyte cytosolic protein 1) (LCP-1) | UniProt NCBI |
| STIM1 | Stromal interaction molecule 1 | UniProt NCBI |
| PLS1 | Plastin-1 (Intestine-specific plastin) (I-plastin) | UniProt NCBI |
| METTL6 | Methyltransferase-like protein 6 (EC 2.1.1.-) | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| CORUM:6108 | 0.0249780992026 | 0.2 | STIM1 | STIM1-TRPV4 complex |
| CORUM:1121 | 0.0499494897235 | 0.2 | WNK1 | WNK1-OSR1 complex |
| CORUM:1123 | 0.0499494897235 | 0.2 | WNK1 | WNK1-SPAK complex |
Edges
| Protein 1 | Protein 2 | Score | Precision | Evidence |
|---|---|---|---|---|
| METTL6 | PLS1 | 0.328 | 0.517 | bioplex (METTL6) bioplex_WMM |
| METTL6 | STIM1 | 0.26 | 0.482 | bioplex (METTL6) bioplex_WMM |
| PLS1 | LCP1 | 0.201 | 0.451 | bioplex (LCP1) bioplex_WMM youn_WMM gupta_WMM treiber_WMM |
| WNK1 | METTL6 | 0.042 | 0.27 | bioplex (METTL6) bioplex_WMM |
| WNK1 | LCP1 | 0.007 | 0.002 | youn_WMM gupta_WMM WMM_only |
| WNK1 | STIM1 | 0.007 | 0.0 | bioplex_WMM youn_WMM WMM_only |
| STIM1 | LCP1 | 0.007 | 0.001 | gupta_WMM WMM_only |
| WNK1 | PLS1 | 0.007 | 0.002 | bioplex_WMM youn_WMM gupta_WMM WMM_only |
| STIM1 | PLS1 | 0.007 | 0.003 | bioplex_WMM youn_WMM WMM_only |
Images
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Complex HuMAP2_02179 has an average edge precision of 0.192 which is ranked 6281 out of all 6965 complexes.
Related Complexes