hu.MAP 2.0: Complex View
Human Protein Complex Map
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Complex: HuMAP2_02186
Confidence: Medium High
Proteins| Genename | Protein Name | Links |
|---|---|---|
| APEH | Acylamino-acid-releasing enzyme (AARE) (EC 3.4.19.1) (Acyl-peptide hydrolase) (APH) (Acylaminoacyl-peptidase) (Oxidized protein hydrolase) (OPH) | UniProt NCBI |
| RRP7A | Ribosomal RNA-processing protein 7 homolog A (Gastric cancer antigen Zg14) | UniProt NCBI |
| LMNB2 | Lamin-B2 | UniProt NCBI |
| SPARC | SPARC (Basement-membrane protein 40) (BM-40) (Osteonectin) (ON) (Secreted protein acidic and rich in cysteine) | UniProt NCBI |
| NOL6 | Nucleolar protein 6 (Nucleolar RNA-associated protein) (Nrap) | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| GO:0032545 | 0.00450823411379 | 0.4 | RRP7A NOL6 | CURI complex |
| GO:0034456 | 0.00450823411379 | 0.4 | RRP7A NOL6 | UTP-C complex |
| KEGG:03008 | 0.0124368761918 | 0.4 | RRP7A NOL6 | Ribosome biogenesis in eukaryotes |
| REAC:R-HSA-6790901 | 0.0237053784759 | 0.4 | RRP7A NOL6 | rRNA modification in the nucleus and cytosol |
| MIRNA:hsa-miR-3158-3p | 0.0258584334602 | 0.4 | RRP7A LMNB2 | hsa-miR-3158-3p |
Edges
| Protein 1 | Protein 2 | Score | Precision | Evidence |
|---|---|---|---|---|
| RRP7A | NOL6 | 0.971 | 0.882 | bioplex (RRP7A) bioplex_WMM youn_WMM gupta_WMM fraction |
| SPARC | LMNB2 | 0.129 | 0.4 | fraction |
| LMNB2 | RRP7A | 0.077 | 0.354 | gupta_WMM fraction |
| LMNB2 | NOL6 | 0.07 | 0.348 | Guru youn_WMM gupta_WMM fraction treiber_WMM |
| LMNB2 | APEH | 0.049 | 0.294 | bioplex_WMM fraction treiber_WMM |
| SPARC | APEH | 0.008 | 0.09 | fraction |
| APEH | NOL6 | 0.007 | 0.003 | bioplex_WMM youn_WMM WMM_only |
| APEH | RRP7A | 0.007 | 0.001 | bioplex_WMM WMM_only |
Images
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Complex HuMAP2_02186 has an average edge precision of 0.296 which is ranked 4642 out of all 6965 complexes.
Related Complexes
| Genename | Complexes |
|---|---|
| APEH | HuMAP2_01805 HuMAP2_02186 HuMAP2_05795 |
| RRP7A | HuMAP2_02186 HuMAP2_02370 HuMAP2_03435 HuMAP2_04524 HuMAP2_06514 |
| LMNB2 | HuMAP2_01147 HuMAP2_02186 HuMAP2_02630 HuMAP2_04524 HuMAP2_05795 HuMAP2_06899 |
| SPARC | HuMAP2_00604 HuMAP2_00809 HuMAP2_02186 HuMAP2_02630 |
| NOL6 | HuMAP2_02186 HuMAP2_02370 HuMAP2_04524 HuMAP2_06514 |