hu.MAP 2.0: Complex View
Human Protein Complex Map
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Complex: HuMAP2_02217
Confidence: Medium High
Proteins| Genename | Protein Name | Links |
|---|---|---|
| TEDC2 | Tubulin epsilon and delta complex protein 2 | UniProt NCBI |
| TUBE1 | Tubulin epsilon chain (Epsilon-tubulin) | UniProt NCBI |
| TUBD1 | Tubulin delta chain (Delta-tubulin) | UniProt NCBI |
| TEDC1 | Tubulin epsilon and delta complex protein 1 | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| WP:WP4536 | 6.69934692649e-08 | 1.0 | TEDC2 TEDC1 TUBE1 TUBD1 | Genes related to primary cilium development (based on CRISPR) |
| GO:0045880 | 0.000246852342475 | 0.75 | TEDC2 TEDC1 TUBD1 | positive regulation of smoothened signaling pathway |
| GO:0044450 | 0.000430977353868 | 1.0 | TEDC2 TEDC1 TUBE1 TUBD1 | microtubule organizing center part |
| GO:0008589 | 0.00447413621813 | 0.75 | TEDC2 TEDC1 TUBD1 | regulation of smoothened signaling pathway |
| GO:0007224 | 0.0189701239271 | 0.75 | TEDC2 TEDC1 TUBD1 | smoothened signaling pathway |
Edges
| Protein 1 | Protein 2 | Score | Precision | Evidence |
|---|---|---|---|---|
| TEDC2 | TUBE1 | 0.983 | 0.899 | hein_WMM bioplex (TUBE1) bioplex_WMM hein (TUBE1) |
| TUBE1 | TUBD1 | 0.87 | 0.804 | hein_WMM bioplex (TUBE1) bioplex_WMM hein (TUBE1) |
| TEDC2 | TEDC1 | 0.127 | 0.398 | bioplex (TEDC2) bioplex_WMM |
| TEDC2 | TUBD1 | 0.012 | 0.15 | hein_WMM bioplex_WMM WMM_only |
| TUBE1 | TEDC1 | 0.011 | 0.151 | bioplex (TUBE1) bioplex_WMM |
| TUBD1 | TEDC1 | 0.007 | 0.005 | bioplex_WMM WMM_only |
Images
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Complex HuMAP2_02217 has an average edge precision of 0.401 which is ranked 3308 out of all 6965 complexes.
Related Complexes
| Genename | Complexes |
|---|---|
| TEDC2 | HuMAP2_02147 HuMAP2_02217 |
| TUBE1 | HuMAP2_02147 HuMAP2_02217 |
| TUBD1 | HuMAP2_02147 HuMAP2_02217 HuMAP2_04444 |
| TEDC1 | HuMAP2_02217 HuMAP2_02900 HuMAP2_05932 |