hu.MAP 2.0: Complex View
Human Protein Complex Map
Search for a protein
Complex: HuMAP2_02229
Confidence: Medium
Proteins| Genename | Protein Name | Links |
|---|---|---|
| ZNF423 | Zinc finger protein 423 (Olf1/EBF-associated zinc finger protein) (hOAZ) (Smad- and Olf-interacting zinc finger protein) | UniProt NCBI |
| SMARCA1 | Probable global transcription activator SNF2L1 (EC 3.6.4.-) (ATP-dependent helicase SMARCA1) (Nucleosome-remodeling factor subunit SNF2L) (SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 1) | UniProt NCBI |
| ZNF521 | Zinc finger protein 521 (Early hematopoietic zinc finger protein) (LYST-interacting protein 3) | UniProt NCBI |
| BPTF | Nucleosome-remodeling factor subunit BPTF (Bromodomain and PHD finger-containing transcription factor) (Fetal Alz-50 clone 1 protein) (Fetal Alzheimer antigen) | UniProt NCBI |
| ZNF512B | Zinc finger protein 512B | UniProt NCBI |
| RBBP7 | Histone-binding protein RBBP7 (Histone acetyltransferase type B subunit 2) (Nucleosome-remodeling factor subunit RBAP46) (Retinoblastoma-binding protein 7) (RBBP-7) (Retinoblastoma-binding protein p46) | UniProt NCBI |
| MTF2 | Metal-response element-binding transcription factor 2 (Metal regulatory transcription factor 2) (Metal-response element DNA-binding protein M96) (Polycomb-like protein 2) (hPCl2) | UniProt NCBI |
| SHPRH | E3 ubiquitin-protein ligase SHPRH (EC 2.3.2.27) (EC 3.6.4.-) (RING-type E3 ubiquitin transferase SHPRH) (SNF2, histone-linker, PHD and RING finger domain-containing helicase) | UniProt NCBI |
| CCDC71 | Coiled-coil domain-containing protein 71 | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| CORUM:100 | 2.52114215054e-08 | 0.333333333333 | SMARCA1 BPTF RBBP7 | hNURF complex |
| CORUM:919 | 2.52114215054e-08 | 0.333333333333 | SMARCA1 BPTF RBBP7 | hNURF complex |
| WP:WP2916 | 0.00232219124631 | 0.222222222222 | MTF2 RBBP7 | Interactome of polycomb repressive complex 2 (PRC2) |
| CORUM:917 | 0.0499262710315 | 0.111111111111 | SMARCA1 | CERF complex (CECR2-containing remodeling factor complex) |
| CORUM:923 | 0.0499262710315 | 0.111111111111 | SMARCA1 | SNF2L-RSF1 complex |
Edges
| Protein 1 | Protein 2 | Score | Precision | Evidence |
|---|---|---|---|---|
| MTF2 | RBBP7 | 0.994 | 0.923 | hein_WMM bioplex (RBBP7) bioplex_WMM |
| RBBP7 | BPTF | 0.985 | 0.899 | bioplex (RBBP7) bioplex_WMM youn_WMM gupta_WMM boldt_WMM |
| ZNF521 | RBBP7 | 0.936 | 0.85 | bioplex (RBBP7) bioplex_WMM |
| ZNF423 | RBBP7 | 0.802 | 0.766 | bioplex (RBBP7) bioplex_WMM |
| RBBP7 | CCDC71 | 0.677 | 0.706 | bioplex (RBBP7) bioplex_WMM |
| RBBP7 | SHPRH | 0.512 | 0.631 | bioplex (RBBP7) bioplex_WMM boldt_WMM |
| ZNF512B | RBBP7 | 0.486 | 0.615 | bioplex (RBBP7) bioplex_WMM youn_WMM gupta_WMM |
| RBBP7 | SMARCA1 | 0.355 | 0.54 | bioplex (RBBP7) bioplex_WMM youn_WMM gupta_WMM |
| ZNF423 | ZNF521 | 0.02 | 0.186 | bioplex_WMM WMM_only |
| SMARCA1 | BPTF | 0.01 | 0.14 | bioplex_WMM youn_WMM WMM_only |
| ZNF521 | CCDC71 | 0.01 | 0.12 | bioplex_WMM WMM_only |
| ZNF512B | BPTF | 0.009 | 0.114 | bioplex_WMM youn_WMM WMM_only |
| BPTF | CCDC71 | 0.009 | 0.103 | bioplex_WMM WMM_only |
| CCDC71 | SHPRH | 0.009 | 0.101 | bioplex_WMM WMM_only |
| ZNF512B | SMARCA1 | 0.009 | 0.092 | bioplex_WMM youn_WMM gupta_WMM WMM_only |
| BPTF | SHPRH | 0.009 | 0.097 | bioplex_WMM WMM_only |
| MTF2 | CCDC71 | 0.009 | 0.098 | bioplex_WMM WMM_only |
| ZNF512B | CCDC71 | 0.009 | 0.096 | bioplex_WMM WMM_only |
| ZNF512B | SHPRH | 0.009 | 0.098 | bioplex_WMM WMM_only |
| ZNF423 | ZNF512B | 0.009 | 0.098 | bioplex_WMM WMM_only |
| MTF2 | BPTF | 0.009 | 0.099 | bioplex_WMM WMM_only |
| MTF2 | SHPRH | 0.009 | 0.099 | bioplex_WMM WMM_only |
| ZNF512B | ZNF521 | 0.009 | 0.098 | bioplex_WMM WMM_only |
| MTF2 | ZNF512B | 0.009 | 0.092 | bioplex_WMM WMM_only |
| ZNF423 | CCDC71 | 0.008 | 0.085 | bioplex_WMM WMM_only |
| ZNF423 | BPTF | 0.008 | 0.081 | bioplex_WMM WMM_only |
| ZNF521 | BPTF | 0.008 | 0.081 | bioplex_WMM WMM_only |
| ZNF521 | SHPRH | 0.008 | 0.08 | bioplex_WMM WMM_only |
| ZNF423 | SHPRH | 0.008 | 0.08 | bioplex_WMM WMM_only |
| SMARCA1 | CCDC71 | 0.008 | 0.067 | bioplex_WMM WMM_only |
| MTF2 | ZNF521 | 0.008 | 0.067 | bioplex_WMM WMM_only |
| MTF2 | ZNF423 | 0.008 | 0.067 | bioplex_WMM WMM_only |
| SMARCA1 | SHPRH | 0.008 | 0.06 | bioplex_WMM WMM_only |
| MTF2 | SMARCA1 | 0.008 | 0.046 | bioplex_WMM WMM_only |
| ZNF521 | SMARCA1 | 0.007 | 0.004 | bioplex_WMM WMM_only |
| ZNF423 | SMARCA1 | 0.007 | 0.004 | bioplex_WMM WMM_only |
Images
Click to enlarge
Complex HuMAP2_02229 has an average edge precision of 0.233 which is ranked 5644 out of all 6965 complexes.
Related Complexes