hu.MAP 2.0: Complex View
Human Protein Complex Map
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Complex: HuMAP2_02263
Confidence: Medium  
Proteins| Genename | Protein Name | Links |
|---|---|---|
| CALCOCO1 | Calcium-binding and coiled-coil domain-containing protein 1 (Calphoglin) (Coiled-coil coactivator protein) (Sarcoma antigen NY-SAR-3) | UniProt   NCBI |
| RTL6 | Retrotransposon Gag-like protein 6 (Leucine zipper protein down-regulated in cancer cells-like) (Mammalian retrotransposon-derived protein 6) (Protein LDOC1L) | UniProt   NCBI |
| NFE2L1 | Endoplasmic reticulum membrane sensor NFE2L1 (Locus control region-factor 1) (LCR-F1) (Nuclear factor erythroid 2-related factor 1) (NF-E2-related factor 1) (NFE2-related factor 1) (Nuclear factor, erythroid derived 2, like 1) (Protein NRF1, p120 form) (Transcription factor 11) (TCF-11) [Cleaved into: Transcription factor NRF1 (Protein NRF1, p110 form)] | UniProt   NCBI |
| ZBTB46 | Zinc finger and BTB domain-containing protein 46 (BTB-ZF protein expressed in effector lymphocytes) (BZEL) (BTB/POZ domain-containing protein 4) (Zinc finger protein 340) | UniProt   NCBI |
| ZBTB10 | Zinc finger and BTB domain-containing protein 10 (Zinc finger protein RIN ZF) | UniProt   NCBI |
| BATF3 | Basic leucine zipper transcriptional factor ATF-like 3 (B-ATF-3) (21 kDa small nuclear factor isolated from T-cells) (Jun dimerization protein p21SNFT) | UniProt   NCBI |
| DEUP1 | Deuterosome assembly protein 1 (Coiled-coil domain-containing protein 67) | UniProt   NCBI |
| NFE2L2 | Nuclear factor erythroid 2-related factor 2 (NF-E2-related factor 2) (NFE2-related factor 2) (HEBP1) (Nuclear factor, erythroid derived 2, like 2) | UniProt   NCBI |
| MAFF | Transcription factor MafF (U-Maf) (V-maf musculoaponeurotic fibrosarcoma oncogene homolog F) | UniProt   NCBI |
| BACH2 | Transcription regulator protein BACH2 (BTB and CNC homolog 2) | UniProt   NCBI |
| LINC01587 |   NCBI | |
| DGKH | Diacylglycerol kinase eta (DAG kinase eta) (EC 2.7.1.107) (Diglyceride kinase eta) (DGK-eta) | UniProt   NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
|   WP:WP4269 | 0.0015050021591 | 0.181818181818 | MAFF NFE2L2 | Ethanol metabolism resulting in production of ROS by CYP2E1 |
|   MIRNA:hsa-miR-132-5p | 0.027715420257 | 0.181818181818 | ZBTB46 NFE2L2 | hsa-miR-132-5p |
|   GO:0000976 | 0.0476413537989 | 0.545454545455 | NFE2L1 BATF3 NFE2L2 MAFF BACH2 CALCOCO1 | transcription regulatory region sequence-specific DNA binding |
Edges
| Protein 1 | Protein 2 | Score | Precision | Evidence |
|---|---|---|---|---|
|  MAFF |  BACH2 | 0.998 | 0.939           | bioplex (MAFF)     bioplex_WMM     |
|  MAFF |  NFE2L1 | 0.974 | 0.886           | bioplex (MAFF)     bioplex_WMM     |
|  RTL6 |  MAFF | 0.544 | 0.643           | bioplex (MAFF)     bioplex_WMM     |
|  DEUP1 |  MAFF | 0.314 | 0.508           | bioplex (DEUP1)     bioplex_WMM     |
|  DGKH |  DEUP1 | 0.227 | 0.468           | bioplex (DEUP1)     bioplex_WMM     |
|  MAFF |  NFE2L2 | 0.169 | 0.426           | bioplex (MAFF)     bioplex_WMM     |
|  BATF3 |  BACH2 | 0.128 | 0.398           | bioplex (BATF3)     bioplex_WMM     |
|  BATF3 |  ZBTB10 | 0.098 | 0.358           | bioplex (BATF3)     bioplex_WMM     |
|  BATF3 |  RTL6 | 0.074 | 0.357           | bioplex (BATF3)     bioplex_WMM     |
|  ZBTB10 |  ZBTB46 | 0.036 | 0.264           | bioplex (ZBTB46)     bioplex_WMM     |
|  MAFF |  CALCOCO1 | 0.036 | 0.264           | bioplex (MAFF)     bioplex_WMM     |
|  LINC01587 |  DGKH | 0.023 | 0.207           | bioplex (LINC01587)     |
|  RTL6 |  BACH2 | 0.01 | 0.119           | bioplex_WMM     WMM_only     |
|  NFE2L1 |  NFE2L2 | 0.01 | 0.105           | bioplex_WMM     WMM_only     |
|  BACH2 |  CALCOCO1 | 0.009 | 0.113           | bioplex_WMM     WMM_only     |
|  BACH2 |  NFE2L1 | 0.009 | 0.107           | bioplex_WMM     WMM_only     |
|  BACH2 |  NFE2L2 | 0.009 | 0.107           | bioplex_WMM     WMM_only     |
|  RTL6 |  NFE2L1 | 0.009 | 0.101           | bioplex_WMM     WMM_only     |
|  RTL6 |  NFE2L2 | 0.009 | 0.101           | bioplex_WMM     WMM_only     |
|  DGKH |  MAFF | 0.008 | 0.085           | bioplex_WMM     WMM_only     |
|  NFE2L1 |  CALCOCO1 | 0.008 | 0.082           | bioplex_WMM     WMM_only     |
|  CALCOCO1 |  NFE2L2 | 0.008 | 0.082           | bioplex_WMM     WMM_only     |
|  RTL6 |  CALCOCO1 | 0.008 | 0.028           | bioplex_WMM     WMM_only     |
|  BACH2 |  ZBTB10 | 0.007 | 0.007           | bioplex_WMM     WMM_only     |
|  RTL6 |  ZBTB10 | 0.007 | 0.004           | bioplex_WMM     WMM_only     |
|  DGKH |  ZBTB10 | 0.007 | 0.003           | youn_WMM     WMM_only     |
Images
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Complex HuMAP2_02263 has an average edge precision of 0.26 which is ranked 5226 out of all 6965 complexes.
Related Complexes
| Genename | Complexes |
|---|---|
| CALCOCO1 | HuMAP2_02263 HuMAP2_03989 HuMAP2_06613 |
| RTL6 | HuMAP2_01275 HuMAP2_01303 HuMAP2_02263 |
| NFE2L1 | HuMAP2_01275 HuMAP2_02263 HuMAP2_02456 HuMAP2_05582 |
| ZBTB46 | HuMAP2_02263 HuMAP2_02539 |
| ZBTB10 | HuMAP2_01303 HuMAP2_02263 HuMAP2_02539 |
| BATF3 | HuMAP2_00167 HuMAP2_01303 HuMAP2_02263 HuMAP2_04193 |
| DEUP1 | HuMAP2_00257 HuMAP2_02263 HuMAP2_02951 |
| NFE2L2 | HuMAP2_02263 HuMAP2_05582 |
| MAFF | HuMAP2_01275 HuMAP2_01303 HuMAP2_02263 HuMAP2_02456 HuMAP2_05582 |
| BACH2 | HuMAP2_01275 HuMAP2_01303 HuMAP2_02263 HuMAP2_02456 HuMAP2_04193 HuMAP2_05582 HuMAP2_05753 |
| LINC01587 | HuMAP2_00257 HuMAP2_02263 HuMAP2_04767 HuMAP2_06459 |
| DGKH | HuMAP2_00257 HuMAP2_02263 HuMAP2_02951 HuMAP2_04767 HuMAP2_06459 |