hu.MAP 2.0: Complex View
Human Protein Complex Map
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Complex: HuMAP2_02264
Confidence: Medium High
Proteins| Genename | Protein Name | Links |
|---|---|---|
| SLC1A3 | Excitatory amino acid transporter 1 (Sodium-dependent glutamate/aspartate transporter 1) (GLAST-1) (Solute carrier family 1 member 3) | UniProt NCBI |
| TMEM45A | Transmembrane protein 45A (DNA polymerase-transactivated protein 4) (Dermal papilla-derived protein 7) | UniProt NCBI |
| KCTD2 | BTB/POZ domain-containing protein KCTD2 (Potassium channel tetramerization domain-containing protein 2) | UniProt NCBI |
| POLK | DNA polymerase kappa (EC 2.7.7.7) (DINB protein) (DINP) | UniProt NCBI |
| KCTD5 | BTB/POZ domain-containing protein KCTD5 | UniProt NCBI |
| KCTD17 | BTB/POZ domain-containing protein KCTD17 | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| GO:0097602 | 0.00123252169378 | 0.5 | KCTD5 KCTD2 KCTD17 | cullin family protein binding |
| GO:0031463 | 0.0140408309691 | 0.5 | KCTD5 KCTD2 KCTD17 | Cul3-RING ubiquitin ligase complex |
Edges
| Protein 1 | Protein 2 | Score | Precision | Evidence |
|---|---|---|---|---|
| KCTD5 | KCTD17 | 0.992 | 0.911 | bioplex (KCTD17) bioplex_WMM boldt_WMM |
| KCTD2 | KCTD17 | 0.991 | 0.909 | bioplex (KCTD17) bioplex_WMM |
| KCTD2 | KCTD5 | 0.572 | 0.655 | hein_WMM bioplex_WMM hein (KCTD5) |
| TMEM45A | KCTD5 | 0.153 | 0.411 | hein_WMM hein (KCTD5) |
| POLK | KCTD17 | 0.15 | 0.41 | bioplex (KCTD17) bioplex_WMM |
| SLC1A3 | KCTD5 | 0.067 | 0.351 | hein_WMM bioplex_WMM hein (KCTD5) |
| POLK | KCTD5 | 0.052 | 0.299 | hein_WMM bioplex_WMM hein (KCTD5,POLK) |
| TMEM45A | SLC1A3 | 0.008 | 0.083 | hein_WMM WMM_only |
| KCTD2 | POLK | 0.008 | 0.066 | hein_WMM bioplex_WMM WMM_only |
| TMEM45A | POLK | 0.008 | 0.034 | hein_WMM WMM_only |
| POLK | SLC1A3 | 0.008 | 0.025 | hein_WMM bioplex_WMM WMM_only |
| TMEM45A | KCTD2 | 0.008 | 0.024 | hein_WMM WMM_only |
| KCTD2 | SLC1A3 | 0.007 | 0.005 | hein_WMM bioplex_WMM WMM_only |
| SLC1A3 | KCTD17 | 0.006 | 0.007 | bioplex (KCTD17) bioplex_WMM |
Images
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Complex HuMAP2_02264 has an average edge precision of 0.299 which is ranked 4605 out of all 6965 complexes.
Related Complexes