hu.MAP 2.0: Complex View
Human Protein Complex Map
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Complex: HuMAP2_02272
Confidence: Very High
Proteins| Genename | Protein Name | Links |
|---|---|---|
| ZC3H11A | Zinc finger CCCH domain-containing protein 11A | UniProt NCBI |
| DDX39B | Spliceosome RNA helicase DDX39B (EC 3.6.4.13) (56 kDa U2AF65-associated protein) (ATP-dependent RNA helicase p47) (DEAD box protein UAP56) (HLA-B-associated transcript 1 protein) | UniProt NCBI |
| THOC1 | THO complex subunit 1 (Tho1) (Nuclear matrix protein p84) (p84N5) (hTREX84) | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| REAC:R-HSA-72187 | 1.11518017806e-05 | 1.0 | ZC3H11A THOC1 DDX39B | mRNA 3'-end processing |
| REAC:R-HSA-73856 | 1.78539429329e-05 | 1.0 | ZC3H11A THOC1 DDX39B | RNA Polymerase II Transcription Termination |
| REAC:R-HSA-159236 | 2.2531998792e-05 | 1.0 | ZC3H11A THOC1 DDX39B | Transport of Mature mRNA derived from an Intron-Containing Transcript |
| GO:0000346 | 2.59741127426e-05 | 1.0 | ZC3H11A THOC1 DDX39B | transcription export complex |
| REAC:R-HSA-72202 | 3.28880140401e-05 | 1.0 | ZC3H11A THOC1 DDX39B | Transport of Mature Transcript to Cytoplasm |
| CORUM:770 | 7.04603414803e-05 | 0.666666666667 | THOC1 DDX39B | TREX complex |
| REAC:R-HSA-72203 | 0.000960089475622 | 1.0 | ZC3H11A THOC1 DDX39B | Processing of Capped Intron-Containing Pre-mRNA |
| KEGG:03040 | 0.00373360278335 | 0.666666666667 | THOC1 DDX39B | Spliceosome |
| KEGG:03013 | 0.00517225695918 | 0.666666666667 | THOC1 DDX39B | RNA transport |
| GO:2000002 | 0.00811409485621 | 0.666666666667 | THOC1 DDX39B | negative regulation of DNA damage checkpoint |
| GO:0031124 | 0.0117851633362 | 1.0 | ZC3H11A THOC1 DDX39B | mRNA 3'-end processing |
| GO:1901977 | 0.0135228859698 | 0.666666666667 | THOC1 DDX39B | negative regulation of cell cycle checkpoint |
| GO:0006406 | 0.0180261250619 | 1.0 | ZC3H11A THOC1 DDX39B | mRNA export from nucleus |
| GO:0071427 | 0.0180261250619 | 1.0 | ZC3H11A THOC1 DDX39B | mRNA-containing ribonucleoprotein complex export from nucleus |
| REAC:R-HSA-8953854 | 0.0206735000409 | 1.0 | ZC3H11A THOC1 DDX39B | Metabolism of RNA |
| GO:0051028 | 0.0206993698472 | 1.0 | ZC3H11A THOC1 DDX39B | mRNA transport |
| GO:0071426 | 0.0268132763851 | 1.0 | ZC3H11A THOC1 DDX39B | ribonucleoprotein complex export from nucleus |
| GO:0071166 | 0.0274836082947 | 1.0 | ZC3H11A THOC1 DDX39B | ribonucleoprotein complex localization |
| GO:0044417 | 0.0283955176165 | 0.666666666667 | THOC1 DDX39B | translocation of molecules into host |
| GO:0051836 | 0.0283955176165 | 0.666666666667 | THOC1 DDX39B | translocation of molecules into other organism involved in symbiotic interaction |
| GO:0046784 | 0.0283955176165 | 0.666666666667 | THOC1 DDX39B | viral mRNA export from host cell nucleus |
| CORUM:351 | 0.0324522040239 | 0.666666666667 | THOC1 DDX39B | Spliceosome |
| GO:0006405 | 0.033252767518 | 1.0 | ZC3H11A THOC1 DDX39B | RNA export from nucleus |
| GO:0031123 | 0.0356085105614 | 1.0 | ZC3H11A THOC1 DDX39B | RNA 3'-end processing |
Edges
| Protein 1 | Protein 2 | Score | Precision | Evidence |
|---|---|---|---|---|
| ZC3H11A | THOC1 | 0.886 | 0.817 | hein_WMM youn (THOC1) bioplex_WMM youn_WMM hein (THOC1) |
| THOC1 | DDX39B | 0.739 | 0.738 | hein_WMM youn (THOC1) bioplex (THOC1) bioplex_WMM youn_WMM hein (THOC1) gupta_WMM |
| ZC3H11A | DDX39B | 0.004 | 0.011 | hein_WMM bioplex_WMM youn_WMM gupta_WMM fraction treiber_WMM |
Images
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Complex HuMAP2_02272 has an average edge precision of 0.522 which is ranked 2386 out of all 6965 complexes.
Related Complexes
| Genename | Complexes |
|---|---|
| ZC3H11A | HuMAP2_00032 HuMAP2_01249 HuMAP2_02272 HuMAP2_05884 HuMAP2_06265 |
| DDX39B | HuMAP2_01249 HuMAP2_01515 HuMAP2_02272 HuMAP2_05884 HuMAP2_06112 HuMAP2_06371 |
| THOC1 | HuMAP2_00032 HuMAP2_00606 HuMAP2_01249 HuMAP2_01295 HuMAP2_02272 HuMAP2_04500 HuMAP2_05884 HuMAP2_06265 |