hu.MAP 2.0: Complex View
Human Protein Complex Map
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Complex: HuMAP2_02285
Confidence: Medium High
Proteins| Genename | Protein Name | Links |
|---|---|---|
| DPYSL5 | Dihydropyrimidinase-related protein 5 (DRP-5) (CRMP3-associated molecule) (CRAM) (Collapsin response mediator protein 5) (CRMP-5) (UNC33-like phosphoprotein 6) (ULIP-6) | UniProt NCBI |
| DPYSL2 | Dihydropyrimidinase-related protein 2 (DRP-2) (Collapsin response mediator protein 2) (CRMP-2) (N2A3) (Unc-33-like phosphoprotein 2) (ULIP-2) | UniProt NCBI |
| UBE2C | Ubiquitin-conjugating enzyme E2 C (EC 2.3.2.23) ((E3-independent) E2 ubiquitin-conjugating enzyme C) (EC 2.3.2.24) (E2 ubiquitin-conjugating enzyme C) (UbcH10) (Ubiquitin carrier protein C) (Ubiquitin-protein ligase C) | UniProt NCBI |
| PPIL3 | Peptidyl-prolyl cis-trans isomerase-like 3 (PPIase) (EC 5.2.1.8) (Cyclophilin J) (CyPJ) (Cyclophilin-like protein PPIL3) (Rotamase PPIL3) | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| REAC:R-HSA-399956 | 0.00120515287053 | 0.5 | DPYSL5 DPYSL2 | CRMPs in Sema3A signaling |
| REAC:R-HSA-373755 | 0.017117349746 | 0.5 | DPYSL5 DPYSL2 | Semaphorin interactions |
| KEGG:04360 | 0.0267154932054 | 0.5 | DPYSL5 DPYSL2 | Axon guidance |
Edges
| Protein 1 | Protein 2 | Score | Precision | Evidence |
|---|---|---|---|---|
| DPYSL5 | DPYSL2 | 0.936 | 0.85 | bioplex (DPYSL5) bioplex_WMM youn_WMM gupta_WMM fraction |
| PPIL3 | DPYSL2 | 0.068 | 0.35 | bioplex_WMM youn_WMM gupta_WMM fraction |
| PPIL3 | UBE2C | 0.05 | 0.298 | fraction |
| PPIL3 | DPYSL5 | 0.047 | 0.294 | bioplex_WMM youn_WMM gupta_WMM fraction |
| UBE2C | DPYSL2 | 0.024 | 0.213 | fraction |
| DPYSL5 | UBE2C | 0.004 | 0.011 | fraction |
Images
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Complex HuMAP2_02285 has an average edge precision of 0.336 which is ranked 4166 out of all 6965 complexes.
Related Complexes
| Genename | Complexes |
|---|---|
| DPYSL5 | HuMAP2_00292 HuMAP2_02285 HuMAP2_02427 HuMAP2_03430 |
| DPYSL2 | HuMAP2_00292 HuMAP2_02285 |
| UBE2C | HuMAP2_00292 HuMAP2_00317 HuMAP2_02285 HuMAP2_02626 HuMAP2_05954 |
| PPIL3 | HuMAP2_00174 HuMAP2_00292 HuMAP2_00317 HuMAP2_02285 HuMAP2_02690 HuMAP2_05912 |