hu.MAP 2.0: Complex View
Human Protein Complex Map
Search for a protein
Complex: HuMAP2_02291
Confidence: Very High
Proteins| Genename | Protein Name | Links |
|---|---|---|
| SPDL1 | Protein Spindly (hSpindly) (Arsenite-related gene 1 protein) (Coiled-coil domain-containing protein 99) (Rhabdomyosarcoma antigen MU-RMS-40.4A) (Spindle apparatus coiled-coil domain-containing protein 1) | UniProt NCBI |
| FNTA | Protein farnesyltransferase/geranylgeranyltransferase type-1 subunit alpha (EC 2.5.1.58) (EC 2.5.1.59) (CAAX farnesyltransferase subunit alpha) (FTase-alpha) (Ras proteins prenyltransferase subunit alpha) (Type I protein geranyl-geranyltransferase subunit alpha) (GGTase-I-alpha) | UniProt NCBI |
| FNTB | Protein farnesyltransferase subunit beta (FTase-beta) (EC 2.5.1.58) (CAAX farnesyltransferase subunit beta) (Ras proteins prenyltransferase subunit beta) | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| CORUM:419 | 3.35600554376e-06 | 0.666666666667 | FNTA FNTB | Farnesyltransferase |
| KEGG:00900 | 0.000103357914858 | 0.666666666667 | FNTA FNTB | Terpenoid backbone biosynthesis |
| REAC:R-HSA-2514859 | 0.00127110038679 | 0.666666666667 | FNTA FNTB | Inactivation, recovery and regulation of the phototransduction cascade |
| GO:0004660 | 0.00135247023414 | 0.666666666667 | FNTA FNTB | protein farnesyltransferase activity |
| GO:0005965 | 0.00135247023414 | 0.666666666667 | FNTA FNTB | protein farnesyltransferase complex |
| REAC:R-HSA-2514856 | 0.00140483748394 | 0.666666666667 | FNTA FNTB | The phototransduction cascade |
| GO:0018343 | 0.00405722906526 | 0.666666666667 | FNTA FNTB | protein farnesylation |
| REAC:R-HSA-2187338 | 0.0185190091635 | 0.666666666667 | FNTA FNTB | Visual phototransduction |
| GO:0008318 | 0.020283420769 | 0.666666666667 | FNTA FNTB | protein prenyltransferase activity |
| GO:0018342 | 0.0486736709081 | 0.666666666667 | FNTA FNTB | protein prenylation |
| GO:0097354 | 0.0486736709081 | 0.666666666667 | FNTA FNTB | prenylation |
Edges
| Protein 1 | Protein 2 | Score | Precision | Evidence |
|---|---|---|---|---|
| FNTA | FNTB | 0.999 | 0.949 | bioplex (FNTB) bioplex_WMM |
| FNTB | SPDL1 | 0.716 | 0.729 | bioplex (FNTB) bioplex_WMM |
| FNTA | SPDL1 | 0.007 | 0.002 | bioplex_WMM WMM_only |
Images
Click to enlarge
Complex HuMAP2_02291 has an average edge precision of 0.56 which is ranked 2127 out of all 6965 complexes.
Related Complexes
| Genename | Complexes |
|---|---|
| SPDL1 | HuMAP2_01791 HuMAP2_02291 HuMAP2_04901 HuMAP2_06753 |
| FNTA | HuMAP2_00121 HuMAP2_00759 HuMAP2_01483 HuMAP2_01541 HuMAP2_02291 HuMAP2_03630 HuMAP2_05557 |
| FNTB | HuMAP2_00121 HuMAP2_00759 HuMAP2_02291 |