hu.MAP 2.0: Complex View
Human Protein Complex Map
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Complex: HuMAP2_02304
Confidence: Very High
Proteins| Genename | Protein Name | Links |
|---|---|---|
| TAF8 | Transcription initiation factor TFIID subunit 8 (Protein taube nuss) (TBP-associated factor 43 kDa) (TBP-associated factor 8) (Transcription initiation factor TFIID 43 kDa subunit) (TAFII-43) (TAFII43) (hTAFII43) | UniProt NCBI |
| TAF6 | Transcription initiation factor TFIID subunit 6 (RNA polymerase II TBP-associated factor subunit E) (Transcription initiation factor TFIID 70 kDa subunit) (TAF(II)70) (TAFII-70) (TAFII70) (Transcription initiation factor TFIID 80 kDa subunit) (TAF(II)80) (TAFII-80) (TAFII80) | UniProt NCBI |
| TAF5 | Transcription initiation factor TFIID subunit 5 (Transcription initiation factor TFIID 100 kDa subunit) (TAF(II)100) (TAFII-100) (TAFII100) | UniProt NCBI |
| TAF9B | Transcription initiation factor TFIID subunit 9B (Neuronal cell death-related protein 7) (DN-7) (Transcription initiation factor TFIID subunit 9-like) (Transcription-associated factor TAFII31L) | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| KEGG:03022 | 2.02266309787e-09 | 1.0 | TAF8 TAF5 TAF6 TAF9B | Basal transcription factors |
| CORUM:514 | 1.48483493479e-07 | 0.75 | TAF9B TAF5 TAF6 | TFIID-beta complex |
| CORUM:513 | 3.77881803953e-07 | 0.75 | TAF9B TAF5 TAF6 | TFTC complex (TATA-binding protein-free TAF-II-containing complex) |
| GO:0005669 | 1.13136855326e-06 | 1.0 | TAF8 TAF5 TAF6 TAF9B | transcription factor TFIID complex |
| REAC:R-HSA-75953 | 2.1849215234e-05 | 0.75 | TAF9B TAF5 TAF6 | RNA Polymerase II Transcription Initiation |
| REAC:R-HSA-73779 | 2.1849215234e-05 | 0.75 | TAF9B TAF5 TAF6 | RNA Polymerase II Transcription Pre-Initiation And Promoter Opening |
| REAC:R-HSA-76042 | 2.1849215234e-05 | 0.75 | TAF9B TAF5 TAF6 | RNA Polymerase II Transcription Initiation And Promoter Clearance |
| REAC:R-HSA-73776 | 2.1849215234e-05 | 0.75 | TAF9B TAF5 TAF6 | RNA Polymerase II Promoter Escape |
| REAC:R-HSA-167162 | 2.1849215234e-05 | 0.75 | TAF9B TAF5 TAF6 | RNA Polymerase II HIV Promoter Escape |
| REAC:R-HSA-167161 | 2.1849215234e-05 | 0.75 | TAF9B TAF5 TAF6 | HIV Transcription Initiation |
| GO:0016591 | 2.50979095633e-05 | 1.0 | TAF8 TAF5 TAF6 TAF9B | RNA polymerase II, holoenzyme |
| CORUM:1321 | 5.02641999304e-05 | 0.5 | TAF5 TAF6 | Transcription initiation factor complex (TAF5, TAF6, TAF9, TAF11, TBP) |
| CORUM:3010 | 5.02641999304e-05 | 0.5 | TAF5 TAF6 | TFIID subcomplex |
| REAC:R-HSA-167172 | 7.69213089466e-05 | 0.75 | TAF9B TAF5 TAF6 | Transcription of the HIV genome |
| GO:0055029 | 8.10410789889e-05 | 1.0 | TAF8 TAF5 TAF6 TAF9B | nuclear DNA-directed RNA polymerase complex |
| GO:0000428 | 8.45267167948e-05 | 1.0 | TAF8 TAF5 TAF6 TAF9B | DNA-directed RNA polymerase complex |
| REAC:R-HSA-6807505 | 8.72293047842e-05 | 0.75 | TAF8 TAF5 TAF6 | RNA polymerase II transcribes snRNA genes |
| GO:0030880 | 9.56604850625e-05 | 1.0 | TAF8 TAF5 TAF6 TAF9B | RNA polymerase complex |
| REAC:R-HSA-674695 | 0.000119121057505 | 0.75 | TAF9B TAF5 TAF6 | RNA Polymerase II Pre-transcription Events |
| GO:0033276 | 0.000132158586819 | 0.75 | TAF9B TAF5 TAF6 | transcription factor TFTC complex |
| REAC:R-HSA-6804756 | 0.000163333735977 | 0.75 | TAF9B TAF5 TAF6 | Regulation of TP53 Activity through Phosphorylation |
| CORUM:155 | 0.000180886312261 | 0.5 | TAF5 TAF6 | TFIID complex |
| CORUM:3009 | 0.000180886312261 | 0.5 | TAF5 TAF6 | TFIID complex |
| CORUM:508 | 0.000226087640536 | 0.5 | TAF5 TAF6 | TFIID complex |
| CORUM:463 | 0.000276304589937 | 0.5 | TAF5 TAF6 | TFIID complex |
| CORUM:484 | 0.000276304589937 | 0.5 | TAF5 TAF6 | TFIID complex |
| CORUM:469 | 0.000331535811226 | 0.5 | TAF5 TAF6 | TFIID-beta complex |
| CORUM:485 | 0.000331535811226 | 0.5 | TAF5 TAF6 | TFIID complex, B-cell specific |
| CORUM:509 | 0.000331535811226 | 0.5 | TAF5 TAF6 | TFIID complex |
| GO:0090575 | 0.000443117561019 | 1.0 | TAF8 TAF5 TAF6 TAF9B | RNA polymerase II transcription factor complex |
| REAC:R-HSA-162599 | 0.000514250934249 | 0.75 | TAF9B TAF5 TAF6 | Late Phase of HIV Life Cycle |
| CORUM:492 | 0.000527301616081 | 0.5 | TAF5 TAF6 | DA complex |
| CORUM:445 | 0.000527301616081 | 0.5 | TAF5 TAF6 | TFTC complex (TATA-binding protein-free TAF-II-containing complex) |
| CORUM:455 | 0.000527301616081 | 0.5 | TAF5 TAF6 | TFTC complex (TATA-binding protein-free TAF-II-containing complex) |
| CORUM:456 | 0.000527301616081 | 0.5 | TAF5 TAF6 | TFTC complex (TATA-binding protein-free TAF-II-containing complex) |
| CORUM:462 | 0.000527301616081 | 0.5 | TAF5 TAF6 | TFTC complex (TATA-binding protein-free TAF-II-containing complex) |
| CORUM:493 | 0.000602576435264 | 0.5 | TAF5 TAF6 | DAB complex |
| CORUM:470 | 0.000602576435264 | 0.5 | TAF5 TAF6 | TFTC complex (TATA-binding protein-free TAF-II-containing complex) |
| REAC:R-HSA-162587 | 0.000681200950707 | 0.75 | TAF9B TAF5 TAF6 | HIV Life Cycle |
| GO:0070461 | 0.000834605087859 | 0.75 | TAF9B TAF5 TAF6 | SAGA-type complex |
| REAC:R-HSA-5633007 | 0.000847823442334 | 0.75 | TAF9B TAF5 TAF6 | Regulation of TP53 Activity |
| GO:0044798 | 0.000921003798055 | 1.0 | TAF8 TAF5 TAF6 TAF9B | nuclear transcription factor complex |
| WP:WP405 | 0.00137286558226 | 0.5 | TAF5 TAF6 | Eukaryotic Transcription Initiation |
| REAC:R-HSA-162906 | 0.00243524237836 | 0.75 | TAF9B TAF5 TAF6 | HIV Infection |
| GO:0061695 | 0.00244665292597 | 1.0 | TAF8 TAF5 TAF6 TAF9B | transferase complex, transferring phosphorus-containing groups |
| GO:0005667 | 0.00406662724791 | 1.0 | TAF8 TAF5 TAF6 TAF9B | transcription factor complex |
| REAC:R-HSA-73857 | 0.00664358115488 | 1.0 | TAF8 TAF5 TAF6 TAF9B | RNA Polymerase II Transcription |
| REAC:R-HSA-3700989 | 0.00924066477779 | 0.75 | TAF9B TAF5 TAF6 | Transcriptional Regulation by TP53 |
| REAC:R-HSA-5663205 | 0.0100576606226 | 0.75 | TAF9B TAF5 TAF6 | Infectious disease |
| REAC:R-HSA-74160 | 0.0102868657133 | 1.0 | TAF8 TAF5 TAF6 TAF9B | Gene expression (Transcription) |
| GO:0042795 | 0.0198185309013 | 0.75 | TAF8 TAF5 TAF6 | snRNA transcription by RNA polymerase II |
| GO:0009301 | 0.0206918321066 | 0.75 | TAF8 TAF5 TAF6 | snRNA transcription |
| GO:0000123 | 0.0275320606423 | 0.75 | TAF9B TAF5 TAF6 | histone acetyltransferase complex |
| GO:1902493 | 0.0396936057372 | 0.75 | TAF9B TAF5 TAF6 | acetyltransferase complex |
| GO:0031248 | 0.0396936057372 | 0.75 | TAF9B TAF5 TAF6 | protein acetyltransferase complex |
Edges
| Protein 1 | Protein 2 | Score | Precision | Evidence |
|---|---|---|---|---|
| TAF5 | TAF8 | 0.997 | 0.929 | bioplex (TAF8) bioplex_WMM youn_WMM |
| TAF8 | TAF6 | 0.993 | 0.918 | bioplex (TAF8) bioplex_WMM youn_WMM |
| TAF5 | TAF9B | 0.993 | 0.918 | bioplex_WMM youn_WMM Malo fraction |
| TAF5 | TAF6 | 0.993 | 0.918 | bioplex_WMM youn_WMM Malo fraction |
| TAF9B | TAF6 | 0.968 | 0.88 | bioplex_WMM youn_WMM Malo gupta_WMM fraction |
| TAF8 | TAF9B | 0.859 | 0.796 | bioplex (TAF8) bioplex_WMM youn_WMM |
Images
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Complex HuMAP2_02304 has an average edge precision of 0.893 which is ranked 606 out of all 6965 complexes.
Related Complexes
| Genename | Complexes |
|---|---|
| TAF8 | HuMAP2_02304 HuMAP2_05057 HuMAP2_05306 HuMAP2_06918 |
| TAF6 | HuMAP2_02304 HuMAP2_05057 |
| TAF5 | HuMAP2_02304 HuMAP2_05057 HuMAP2_06666 |
| TAF9B | HuMAP2_02304 HuMAP2_04385 HuMAP2_05057 HuMAP2_05306 HuMAP2_06169 HuMAP2_06947 |