hu.MAP 2.0: Complex View
Human Protein Complex Map
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Complex: HuMAP2_02311
Confidence: Extremely High
Proteins| Genename | Protein Name | Links |
|---|---|---|
| RANGAP1 | Ran GTPase-activating protein 1 (RanGAP1) | UniProt NCBI |
| RANBP2 | E3 SUMO-protein ligase RanBP2 (EC 2.3.2.-) (358 kDa nucleoporin) (Nuclear pore complex protein Nup358) (Nucleoporin Nup358) (Ran-binding protein 2) (RanBP2) (p270) | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| REAC:R-HSA-165054 | 0.000779304410004 | 1.0 | RANBP2 RANGAP1 | Rev-mediated nuclear export of HIV RNA |
| REAC:R-HSA-177243 | 0.000884887588134 | 1.0 | RANBP2 RANGAP1 | Interactions of Rev with host cellular proteins |
| REAC:R-HSA-4615885 | 0.0014429701011 | 1.0 | RANBP2 RANGAP1 | SUMOylation of DNA replication proteins |
| KEGG:03013 | 0.00169649664321 | 1.0 | RANBP2 RANGAP1 | RNA transport |
| REAC:R-HSA-141444 | 0.0070154156135 | 1.0 | RANBP2 RANGAP1 | Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal |
| REAC:R-HSA-141424 | 0.0070154156135 | 1.0 | RANBP2 RANGAP1 | Amplification of signal from the kinetochores |
| REAC:R-HSA-69618 | 0.00950416195513 | 1.0 | RANBP2 RANGAP1 | Mitotic Spindle Checkpoint |
| REAC:R-HSA-2500257 | 0.0119660935214 | 1.0 | RANBP2 RANGAP1 | Resolution of Sister Chromatid Cohesion |
| REAC:R-HSA-162909 | 0.0123699910758 | 1.0 | RANBP2 RANGAP1 | Host Interactions of HIV factors |
| REAC:R-HSA-162599 | 0.0147112561527 | 1.0 | RANBP2 RANGAP1 | Late Phase of HIV Life Cycle |
| REAC:R-HSA-5663220 | 0.0147112561527 | 1.0 | RANBP2 RANGAP1 | RHO GTPases Activate Formins |
| REAC:R-HSA-162587 | 0.0177396498492 | 1.0 | RANBP2 RANGAP1 | HIV Life Cycle |
| REAC:R-HSA-3108232 | 0.0229517718172 | 1.0 | RANBP2 RANGAP1 | SUMO E3 ligases SUMOylate target proteins |
| REAC:R-HSA-2990846 | 0.0246461304377 | 1.0 | RANBP2 RANGAP1 | SUMOylation |
| REAC:R-HSA-2467813 | 0.0279091534189 | 1.0 | RANBP2 RANGAP1 | Separation of Sister Chromatids |
| REAC:R-HSA-68877 | 0.0304096312248 | 1.0 | RANBP2 RANGAP1 | Mitotic Prometaphase |
| REAC:R-HSA-68882 | 0.0304096312248 | 1.0 | RANBP2 RANGAP1 | Mitotic Anaphase |
| REAC:R-HSA-2555396 | 0.0307297326061 | 1.0 | RANBP2 RANGAP1 | Mitotic Metaphase and Anaphase |
| MIRNA:hsa-miR-3124-3p | 0.0390125199064 | 1.0 | RANBP2 RANGAP1 | hsa-miR-3124-3p |
| REAC:R-HSA-162906 | 0.0414841334642 | 1.0 | RANBP2 RANGAP1 | HIV Infection |
| HP:0011887 | 0.0497341708567 | 0.5 | RANBP2 | Choroid hemorrhage |
| HP:0031982 | 0.0497341708567 | 0.5 | RANBP2 | Abnormal putamen morphology |
Edges
| Protein 1 | Protein 2 | Score | Precision | Evidence |
|---|---|---|---|---|
| RANGAP1 | RANBP2 | 1.0 | 0.949 | hein_WMM bioplex_WMM Guru hein (RANBP2) Malo gupta_WMM fraction treiber_WMM |
Images
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Complex HuMAP2_02311 has an average edge precision of 0.949 which is ranked 5 out of all 6965 complexes.
Related Complexes
| Genename | Complexes |
|---|---|
| RANGAP1 | HuMAP2_00414 HuMAP2_00926 HuMAP2_01457 HuMAP2_02311 HuMAP2_03020 HuMAP2_06826 |
| RANBP2 | HuMAP2_00926 HuMAP2_02311 HuMAP2_03020 HuMAP2_06826 |