hu.MAP 2.0: Complex View
Human Protein Complex Map
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Complex: HuMAP2_02312
Confidence: Medium High
Proteins| Genename | Protein Name | Links |
|---|---|---|
| WASHC2C | WASH complex subunit 2C (Vaccinia virus penetration factor) (VPEF) | UniProt NCBI |
| WASHC2A | WASH complex subunit 2A | UniProt NCBI |
| VPS26A | Vacuolar protein sorting-associated protein 26A (Vesicle protein sorting 26A) (hVPS26) | UniProt NCBI |
| TBC1D5 | TBC1 domain family member 5 | UniProt NCBI |
| ENTR1 | Endosome-associated-trafficking regulator 1 (Antigen NY-CO-3) (Serologically defined colon cancer antigen 3) | UniProt NCBI |
| VPS26B | Vacuolar protein sorting-associated protein 26B (Vesicle protein sorting 26B) | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| GO:0016197 | 2.72047361196e-07 | 1.0 | WASHC2A VPS26B VPS26A TBC1D5 WASHC2C ENTR1 | endosomal transport |
| GO:0030904 | 1.11807235637e-06 | 0.666666666667 | ENTR1 VPS26B VPS26A TBC1D5 | retromer complex |
| GO:0042147 | 1.2539847452e-06 | 0.833333333333 | WASHC2C WASHC2A VPS26B VPS26A TBC1D5 | retrograde transport, endosome to Golgi |
| GO:0016482 | 2.26451406257e-05 | 0.833333333333 | WASHC2C WASHC2A VPS26B VPS26A TBC1D5 | cytosolic transport |
| KEGG:04144 | 3.82138813702e-05 | 0.666666666667 | VPS26B WASHC2A VPS26A WASHC2C | Endocytosis |
| GO:0005769 | 0.00017333127517 | 0.833333333333 | VPS26B WASHC2A ENTR1 VPS26A WASHC2C | early endosome |
| GO:0005768 | 0.000228199057774 | 1.0 | WASHC2A VPS26B VPS26A TBC1D5 WASHC2C ENTR1 | endosome |
| GO:1990126 | 0.00416378298645 | 0.5 | WASHC2C VPS26A ENTR1 | retrograde transport, endosome to plasma membrane |
| GO:0046907 | 0.038148924612 | 1.0 | WASHC2A VPS26B VPS26A TBC1D5 WASHC2C ENTR1 | intracellular transport |
| GO:1905394 | 0.0405595771497 | 0.333333333333 | WASHC2C TBC1D5 | retromer complex binding |
| GO:0030906 | 0.0405595771497 | 0.333333333333 | VPS26B VPS26A | retromer, cargo-selective complex |
Edges
| Protein 1 | Protein 2 | Score | Precision | Evidence |
|---|---|---|---|---|
| VPS26A | TBC1D5 | 1.0 | 0.949 | hein_WMM bioplex (VPS26A) bioplex_WMM hein (VPS26A) gupta_WMM |
| VPS26B | TBC1D5 | 1.0 | 0.949 | hein_WMM bioplex (VPS26B) bioplex_WMM hein (VPS26B) |
| VPS26B | VPS26A | 0.888 | 0.818 | bioplex (VPS26A,VPS26B) bioplex_WMM fraction |
| VPS26A | WASHC2A | 0.121 | 0.393 | hein_WMM hein (VPS26A) gupta_WMM |
| VPS26A | WASHC2C | 0.108 | 0.373 | hein_WMM hein (VPS26A) gupta_WMM |
| VPS26A | ENTR1 | 0.057 | 0.321 | hein_WMM hein (VPS26A) gupta_WMM |
| WASHC2A | WASHC2C | 0.015 | 0.147 | hein_WMM bioplex_WMM youn_WMM gupta_WMM WMM_only boldt_WMM |
| ENTR1 | WASHC2A | 0.015 | 0.138 | hein_WMM youn (ENTR1) youn_WMM gupta_WMM |
| TBC1D5 | WASHC2A | 0.009 | 0.09 | hein_WMM youn_WMM gupta_WMM WMM_only |
| TBC1D5 | WASHC2C | 0.008 | 0.067 | hein_WMM gupta_WMM WMM_only |
| ENTR1 | WASHC2C | 0.007 | 0.01 | hein_WMM youn_WMM gupta_WMM WMM_only |
| TBC1D5 | ENTR1 | 0.007 | 0.004 | hein_WMM youn (ENTR1) youn_WMM gupta_WMM |
| VPS26B | WASHC2A | 0.006 | 0.003 | hein_WMM hein (VPS26B) |
| VPS26B | ENTR1 | 0.006 | 0.009 | hein_WMM hein (VPS26B) |
Images
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Complex HuMAP2_02312 has an average edge precision of 0.305 which is ranked 4498 out of all 6965 complexes.
Related Complexes