hu.MAP 2.0: Complex View
Human Protein Complex Map
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Complex: HuMAP2_02313
Confidence: Medium
Proteins| Genename | Protein Name | Links |
|---|---|---|
| NEUROG2 | Neurogenin-2 (NGN-2) (Class A basic helix-loop-helix protein 8) (bHLHa8) (Protein atonal homolog 4) | UniProt NCBI |
| SSR1 | Translocon-associated protein subunit alpha (TRAP-alpha) (Signal sequence receptor subunit alpha) (SSR-alpha) | UniProt NCBI |
| SRP9 | Signal recognition particle 9 kDa protein (SRP9) | UniProt NCBI |
| SRP54 | Signal recognition particle 54 kDa protein (SRP54) | UniProt NCBI |
| SRP19 | Signal recognition particle 19 kDa protein (SRP19) | UniProt NCBI |
| RPS25 | 40S ribosomal protein S25 (Small ribosomal subunit protein eS25) | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| REAC:R-HSA-1799339 | 2.05315496829e-08 | 0.833333333333 | RPS25 SRP19 SRP54 SSR1 SRP9 | SRP-dependent cotranslational protein targeting to membrane |
| REAC:R-HSA-72766 | 2.61823790042e-06 | 0.833333333333 | RPS25 SRP19 SRP54 SSR1 SRP9 | Translation |
| KEGG:03060 | 2.96952116806e-06 | 0.5 | SRP19 SRP9 SRP54 | Protein export |
| GO:0006613 | 2.98904170003e-06 | 0.833333333333 | RPS25 SRP19 SRP54 SSR1 SRP9 | cotranslational protein targeting to membrane |
| GO:0005786 | 3.63109651748e-05 | 0.5 | SRP19 SRP9 SRP54 | signal recognition particle, endoplasmic reticulum targeting |
| GO:0006612 | 4.52862421777e-05 | 0.833333333333 | RPS25 SRP19 SRP54 SSR1 SRP9 | protein targeting to membrane |
| GO:0048500 | 0.000101639975642 | 0.5 | SRP19 SRP9 SRP54 | signal recognition particle |
| GO:0090150 | 0.000547541386546 | 0.833333333333 | RPS25 SRP19 SRP54 SSR1 SRP9 | establishment of protein localization to membrane |
| GO:0006614 | 0.000926409268263 | 0.666666666667 | RPS25 SRP19 SRP9 SRP54 | SRP-dependent cotranslational protein targeting to membrane |
| GO:0045047 | 0.00166457765781 | 0.666666666667 | RPS25 SRP19 SRP9 SRP54 | protein targeting to ER |
| GO:0072599 | 0.00193921959428 | 0.666666666667 | RPS25 SRP19 SRP9 SRP54 | establishment of protein localization to endoplasmic reticulum |
| GO:0006605 | 0.00236068657071 | 0.833333333333 | RPS25 SRP19 SRP54 SSR1 SRP9 | protein targeting |
| GO:0070972 | 0.00422920591485 | 0.666666666667 | RPS25 SRP19 SRP9 SRP54 | protein localization to endoplasmic reticulum |
| GO:0006617 | 0.00676235117068 | 0.333333333333 | SRP54 SRP19 | SRP-dependent cotranslational protein targeting to membrane, signal sequence recognition |
| GO:0072657 | 0.0116012507947 | 0.833333333333 | RPS25 SRP19 SRP54 SSR1 SRP9 | protein localization to membrane |
| REAC:R-HSA-392499 | 0.0232605972232 | 0.833333333333 | RPS25 SRP19 SRP54 SSR1 SRP9 | Metabolism of proteins |
Edges
| Protein 1 | Protein 2 | Score | Precision | Evidence |
|---|---|---|---|---|
| SRP54 | SRP19 | 0.998 | 0.941 | hein_WMM bioplex_WMM youn_WMM Malo gupta_WMM fraction |
| SRP9 | SRP54 | 0.223 | 0.467 | bioplex (SRP9) bioplex_WMM youn_WMM gupta_WMM fraction |
| SRP9 | RPS25 | 0.182 | 0.437 | hein_WMM bioplex (SRP9) bioplex_WMM boldt youn_WMM gupta_WMM fraction boldt_WMM treiber_WMM |
| SSR1 | RPS25 | 0.073 | 0.357 | bioplex_WMM boldt fraction boldt_WMM |
| SRP9 | SRP19 | 0.06 | 0.333 | bioplex (SRP9) bioplex_WMM youn_WMM gupta_WMM |
| SRP9 | NEUROG2 | 0.025 | 0.211 | fraction |
| SRP54 | RPS25 | 0.008 | 0.032 | hein_WMM youn_WMM WMM_only |
| SRP54 | SSR1 | 0.007 | 0.004 | youn_WMM gupta_WMM WMM_only |
| SRP19 | RPS25 | 0.007 | 0.001 | hein_WMM youn_WMM WMM_only treiber_WMM |
| SRP19 | SSR1 | 0.007 | 0.001 | gupta_WMM WMM_only |
| SRP9 | SSR1 | 0.006 | 0.003 | bioplex (SRP9) bioplex_WMM boldt youn_WMM gupta_WMM boldt_WMM |
Images
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Complex HuMAP2_02313 has an average edge precision of 0.253 which is ranked 5325 out of all 6965 complexes.
Related Complexes