hu.MAP 2.0: Complex View
Human Protein Complex Map
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Complex: HuMAP2_02334
Confidence: Medium High
Proteins| Genename | Protein Name | Links |
|---|---|---|
| C1S | Complement C1s subcomponent (EC 3.4.21.42) (C1 esterase) (Complement component 1 subcomponent s) [Cleaved into: Complement C1s subcomponent heavy chain; Complement C1s subcomponent light chain] | UniProt NCBI |
| C1R | Complement C1r subcomponent (EC 3.4.21.41) (Complement component 1 subcomponent r) [Cleaved into: Complement C1r subcomponent heavy chain; Complement C1r subcomponent light chain] | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| REAC:R-HSA-173623 | 0.0399649587242 | 1.0 | C1S | Classical antibody-mediated complement activation |
| WP:WP545 | 0.0498572752401 | 1.0 | C1S | Complement Activation |
Edges
| Protein 1 | Protein 2 | Score | Precision | Evidence |
|---|---|---|---|---|
| C1S | C1R | 0.154 | 0.414 | bioplex (C1S) bioplex_WMM |
Images
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Complex HuMAP2_02334 has an average edge precision of 0.414 which is ranked 3162 out of all 6965 complexes.
Related Complexes
| Genename | Complexes |
|---|---|
| C1S | HuMAP2_02334 HuMAP2_02426 HuMAP2_03906 |
| C1R | HuMAP2_02334 HuMAP2_02426 |