hu.MAP 2.0: Complex View

Human Protein Complex Map

Complex: HuMAP2_02337

Confidence: Medium

Genename	Protein Name	Links
FAM13A	Protein FAM13A	UniProt NCBI
AVPI1	Arginine vasopressin-induced protein 1 (AVP-induced protein 1)	UniProt NCBI
PALD1	Paladin	UniProt NCBI
FMNL2	Formin-like protein 2 (Formin homology 2 domain-containing protein 2)	UniProt NCBI
NR1H3	Oxysterols receptor LXR-alpha (Liver X receptor alpha) (Nuclear receptor subfamily 1 group H member 3)	UniProt NCBI
PRKG2	cGMP-dependent protein kinase 2 (cGK 2) (cGK2) (EC 2.7.11.12) (cGMP-dependent protein kinase II) (cGKII)	UniProt NCBI
LZTS1	Leucine zipper putative tumor suppressor 1 (F37/esophageal cancer-related gene-coding leucine-zipper motif) (Fez1)	UniProt NCBI
OCC1	Overexpressed in colon carcinoma 1 protein (OCC-1) (AGD3)	UniProt NCBI
UNC119	Protein unc-119 homolog A (Retinal protein 4) (hRG4)	UniProt NCBI
GNAT2	Guanine nucleotide-binding protein G(t) subunit alpha-2 (Transducin alpha-2 chain)	UniProt NCBI
PSKH2	Serine/threonine-protein kinase H2 (EC 2.7.11.1) (Protein serine kinase H2) (PSK-H2)	UniProt NCBI
PDE8A	High affinity cAMP-specific and IBMX-insensitive 3',5'-cyclic phosphodiesterase 8A (EC 3.1.4.53)	UniProt NCBI
PDE9A	High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A (EC 3.1.4.35)	UniProt NCBI
LIMK2	LIM domain kinase 2 (LIMK-2) (EC 2.7.11.1)	UniProt NCBI
RNF34	E3 ubiquitin-protein ligase RNF34 (EC 2.3.2.27) (Caspase regulator CARP1) (Caspases-8 and -10-associated RING finger protein 1) (CARP-1) (FYVE-RING finger protein Momo) (Human RING finger homologous to inhibitor of apoptosis protein) (hRFI) (RING finger protein 34) (RING finger protein RIFF) (RING-type E3 ubiquitin transferase RNF34)	UniProt NCBI
PSKH1	Serine/threonine-protein kinase H1 (EC 2.7.11.1) (Protein serine kinase H1) (PSK-H1)	UniProt NCBI
UNC119B	Protein unc-119 homolog B	UniProt NCBI

Enrichments

Term ID	Corrected Pval	Fraction Complex Coverage	Proteins	Term Name
REAC:R-HSA-418457	0.0233692097873	0.117647058824	PRKG2 PDE9A	cGMP effects

Edges

Protein 1	Protein 2	Score	Precision	Evidence
PDE9A	UNC119	0.986	0.901	bioplex (UNC119) bioplex_WMM boldt (UNC119) boldt_WMM
PDE8A	UNC119	0.978	0.894	bioplex (UNC119) bioplex_WMM boldt (UNC119) boldt_WMM
PALD1	UNC119	0.977	0.893	bioplex (UNC119) bioplex_WMM boldt (UNC119) boldt_WMM
PRKG2	UNC119	0.886	0.817	bioplex (UNC119) bioplex_WMM boldt (UNC119) boldt_WMM
AVPI1	UNC119	0.767	0.75	bioplex (UNC119) bioplex_WMM
UNC119	UNC119B	0.454	0.595	bioplex (UNC119) bioplex_WMM boldt boldt_WMM
OCC1	UNC119	0.252	0.476	bioplex (UNC119) bioplex_WMM boldt (UNC119) boldt_WMM
LZTS1	UNC119	0.241	0.468	bioplex (UNC119) bioplex_WMM
RNF34	UNC119B	0.234	0.47	bioplex (RNF34) bioplex_WMM
UNC119	PSKH1	0.115	0.384	bioplex (UNC119) bioplex_WMM
UNC119	RNF34	0.103	0.366	bioplex (RNF34,UNC119) bioplex_WMM boldt (UNC119) boldt_WMM
PSKH2	UNC119B	0.077	0.354	bioplex (PSKH2) bioplex_WMM
FAM13A	UNC119	0.073	0.357	bioplex (FAM13A,UNC119) bioplex_WMM
PSKH2	UNC119	0.069	0.348	bioplex (PSKH2) bioplex_WMM
UNC119	LIMK2	0.066	0.348	bioplex (LIMK2,UNC119) bioplex_WMM
UNC119	FMNL2	0.064	0.35	bioplex (UNC119) bioplex_WMM boldt (UNC119) boldt_WMM
UNC119	GNAT2	0.047	0.291	bioplex (GNAT2) bioplex_WMM
NR1H3	PDE8A	0.028	0.231	bioplex (NR1H3) bioplex_WMM
LZTS1	UNC119B	0.01	0.122	bioplex_WMM youn_WMM WMM_only
FAM13A	UNC119B	0.01	0.106	bioplex (FAM13A) bioplex_WMM
PALD1	PSKH1	0.009	0.091	bioplex_WMM WMM_only
AVPI1	PALD1	0.009	0.091	bioplex_WMM WMM_only
FMNL2	PSKH1	0.009	0.095	bioplex_WMM WMM_only
PRKG2	AVPI1	0.009	0.095	bioplex_WMM WMM_only
PRKG2	PSKH1	0.009	0.095	bioplex_WMM WMM_only
PDE9A	AVPI1	0.009	0.095	bioplex_WMM WMM_only
AVPI1	FMNL2	0.009	0.095	bioplex_WMM WMM_only
PDE9A	PSKH1	0.009	0.095	bioplex_WMM WMM_only
AVPI1	PSKH1	0.009	0.095	bioplex_WMM WMM_only
PALD1	FMNL2	0.009	0.096	bioplex_WMM boldt youn_WMM boldt_WMM
PDE9A	PALD1	0.009	0.097	bioplex_WMM boldt boldt_WMM
PDE9A	FMNL2	0.009	0.098	bioplex_WMM boldt boldt_WMM
LZTS1	PALD1	0.008	0.095	bioplex_WMM youn_WMM WMM_only
PRKG2	PALD1	0.008	0.096	bioplex_WMM boldt boldt_WMM
PDE8A	AVPI1	0.008	0.091	bioplex_WMM WMM_only
LZTS1	PDE9A	0.008	0.091	bioplex_WMM WMM_only
PDE8A	PSKH1	0.008	0.091	bioplex_WMM WMM_only
LZTS1	PRKG2	0.008	0.091	bioplex_WMM WMM_only
LZTS1	FMNL2	0.008	0.091	bioplex_WMM WMM_only
LZTS1	AVPI1	0.008	0.091	bioplex_WMM WMM_only
LZTS1	PSKH1	0.008	0.091	bioplex_WMM WMM_only
PRKG2	FMNL2	0.008	0.091	bioplex_WMM boldt boldt_WMM
PRKG2	PDE9A	0.008	0.088	bioplex_WMM boldt boldt_WMM
PDE8A	PALD1	0.008	0.085	bioplex_WMM boldt youn_WMM boldt_WMM
PDE8A	FMNL2	0.008	0.088	bioplex_WMM boldt boldt_WMM
PDE8A	PDE9A	0.008	0.088	bioplex_WMM boldt boldt_WMM
FAM13A	PALD1	0.008	0.089	bioplex_WMM WMM_only
FAM13A	FMNL2	0.008	0.087	bioplex_WMM WMM_only
FAM13A	AVPI1	0.008	0.087	bioplex_WMM WMM_only
FAM13A	PSKH1	0.008	0.087	bioplex_WMM WMM_only
PRKG2	FAM13A	0.008	0.087	bioplex_WMM WMM_only
FAM13A	PDE9A	0.008	0.087	bioplex_WMM WMM_only
PALD1	LIMK2	0.008	0.084	bioplex_WMM WMM_only
PRKG2	LIMK2	0.008	0.085	bioplex_WMM WMM_only
LIMK2	FMNL2	0.008	0.085	bioplex_WMM WMM_only
AVPI1	LIMK2	0.008	0.085	bioplex_WMM WMM_only
PDE9A	LIMK2	0.008	0.085	bioplex_WMM WMM_only
LIMK2	PSKH1	0.008	0.085	bioplex_WMM WMM_only
LZTS1	PDE8A	0.008	0.085	bioplex_WMM WMM_only
PRKG2	PDE8A	0.008	0.081	bioplex_WMM boldt boldt_WMM
RNF34	PSKH1	0.008	0.082	bioplex_WMM WMM_only
AVPI1	RNF34	0.008	0.082	bioplex_WMM WMM_only
FAM13A	PDE8A	0.008	0.067	bioplex_WMM WMM_only
LZTS1	FAM13A	0.008	0.067	bioplex_WMM WMM_only
PDE9A	RNF34	0.008	0.067	bioplex_WMM boldt boldt_WMM
RNF34	FMNL2	0.008	0.066	bioplex_WMM boldt boldt_WMM
PALD1	RNF34	0.008	0.067	bioplex_WMM boldt boldt_WMM
PDE8A	LIMK2	0.008	0.06	bioplex_WMM WMM_only
LZTS1	LIMK2	0.008	0.06	bioplex_WMM WMM_only
GNAT2	UNC119B	0.008	0.06	bioplex (GNAT2) bioplex_WMM
PRKG2	RNF34	0.008	0.057	bioplex_WMM boldt boldt_WMM
LZTS1	RNF34	0.008	0.046	bioplex_WMM WMM_only
OCC1	PSKH1	0.008	0.046	bioplex_WMM WMM_only
OCC1	AVPI1	0.008	0.046	bioplex_WMM WMM_only
PALD1	UNC119B	0.008	0.044	bioplex_WMM youn_WMM WMM_only
FAM13A	LIMK2	0.008	0.04	bioplex_WMM WMM_only
PDE9A	UNC119B	0.008	0.031	bioplex_WMM WMM_only
FMNL2	UNC119B	0.008	0.031	bioplex_WMM WMM_only
PSKH1	UNC119B	0.008	0.031	bioplex_WMM WMM_only
PRKG2	UNC119B	0.008	0.031	bioplex_WMM WMM_only
AVPI1	UNC119B	0.008	0.031	bioplex_WMM WMM_only
PDE8A	RNF34	0.008	0.032	bioplex_WMM boldt boldt_WMM
FAM13A	RNF34	0.008	0.028	bioplex_WMM WMM_only
OCC1	PALD1	0.008	0.028	bioplex_WMM boldt boldt_WMM
OCC1	FMNL2	0.008	0.026	bioplex_WMM boldt boldt_WMM
OCC1	PDE9A	0.008	0.023	bioplex_WMM boldt boldt_WMM
LIMK2	RNF34	0.008	0.028	bioplex_WMM WMM_only
LZTS1	OCC1	0.008	0.029	bioplex_WMM WMM_only
PDE8A	UNC119B	0.008	0.011	bioplex_WMM WMM_only
PRKG2	OCC1	0.008	0.012	bioplex_WMM boldt boldt_WMM
FAM13A	OCC1	0.007	0.01	bioplex_WMM WMM_only
OCC1	PDE8A	0.007	0.008	bioplex_WMM boldt boldt_WMM
OCC1	LIMK2	0.007	0.007	bioplex_WMM WMM_only
OCC1	RNF34	0.007	0.004	bioplex_WMM boldt boldt_WMM
OCC1	UNC119B	0.007	0.002	bioplex_WMM WMM_only
LIMK2	UNC119B	0.004	0.013	bioplex (LIMK2) bioplex_WMM
NR1H3	UNC119	0.004	0.011	bioplex (NR1H3)

Images

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Complex HuMAP2_02337 has an average edge precision of 0.15 which is ranked 6705 out of all 6965 complexes.

Related Complexes

Genename	Complexes
FAM13A	HuMAP2_02337
AVPI1	HuMAP2_02337
PALD1	HuMAP2_02337
FMNL2	HuMAP2_02337
NR1H3	HuMAP2_02337 HuMAP2_05540
PRKG2	HuMAP2_02337
LZTS1	HuMAP2_02173 HuMAP2_02337 HuMAP2_03011 HuMAP2_03772
OCC1	HuMAP2_02337
UNC119	HuMAP2_02337
GNAT2	HuMAP2_02337 HuMAP2_06727
PSKH2	HuMAP2_02337 HuMAP2_04784 HuMAP2_06166
PDE8A	HuMAP2_02337 HuMAP2_05540
PDE9A	HuMAP2_02337
LIMK2	HuMAP2_02337 HuMAP2_03898 HuMAP2_05568
RNF34	HuMAP2_02337 HuMAP2_02996
PSKH1	HuMAP2_02337
UNC119B	HuMAP2_02337 HuMAP2_02996

hu.MAP 2.0: Complex View

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Complex: HuMAP2_02337