hu.MAP 2.0: Complex View
Human Protein Complex Map
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Complex: HuMAP2_02348
Confidence: Medium
Proteins| Genename | Protein Name | Links |
|---|---|---|
| SKA3 | Spindle and kinetochore-associated protein 3 | UniProt NCBI |
| SKA2 | Spindle and kinetochore-associated protein 2 (Protein FAM33A) | UniProt NCBI |
| CCDC85B | Coiled-coil domain-containing protein 85B (Hepatitis delta antigen-interacting protein A) (Delta-interacting protein A) | UniProt NCBI |
| SKA1 | Spindle and kinetochore-associated protein 1 | UniProt NCBI |
| RALYL | RNA-binding Raly-like protein (hRALYL) (Heterogeneous nuclear ribonucleoprotein C-like 3) (hnRNP core protein C-like 3) | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| GO:0000940 | 0.000330213415772 | 0.6 | SKA3 SKA2 SKA1 | condensed chromosome outer kinetochore |
| GO:0000777 | 0.00367721278555 | 0.6 | SKA3 SKA2 SKA1 | condensed chromosome kinetochore |
| GO:0000779 | 0.00826983957236 | 0.6 | SKA3 SKA2 SKA1 | condensed chromosome, centromeric region |
| GO:0005876 | 0.0199719657189 | 0.6 | SKA3 SKA2 SKA1 | spindle microtubule |
| GO:0031110 | 0.0412952841175 | 0.6 | SKA3 SKA2 SKA1 | regulation of microtubule polymerization or depolymerization |
| CORUM:1057 | 0.0499494897235 | 0.2 | CCDC85B | DIPA-MCRS1 complex |
Edges
| Protein 1 | Protein 2 | Score | Precision | Evidence |
|---|---|---|---|---|
| SKA1 | SKA3 | 1.0 | 0.949 | hein_WMM bioplex (SKA3) bioplex_WMM youn_WMM hein (SKA1,SKA3) gupta_WMM |
| SKA2 | SKA3 | 1.0 | 0.949 | hein_WMM bioplex (SKA3) bioplex_WMM youn_WMM hein (SKA3) gupta_WMM |
| SKA1 | SKA2 | 0.874 | 0.806 | hein_WMM bioplex_WMM youn_WMM hein (SKA1) gupta_WMM |
| SKA2 | RALYL | 0.103 | 0.366 | bioplex (RALYL) bioplex_WMM |
| SKA3 | CCDC85B | 0.021 | 0.188 | bioplex (SKA3) bioplex_WMM |
| SKA2 | CCDC85B | 0.007 | 0.007 | bioplex_WMM WMM_only |
| SKA1 | CCDC85B | 0.007 | 0.006 | bioplex_WMM WMM_only |
| SKA1 | RALYL | 0.007 | 0.004 | youn_WMM WMM_only |
| SKA3 | RALYL | 0.007 | 0.0 | youn_WMM WMM_only |
Images
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Complex HuMAP2_02348 has an average edge precision of 0.364 which is ranked 3707 out of all 6965 complexes.
Related Complexes
| Genename | Complexes |
|---|---|
| SKA3 | HuMAP2_00554 HuMAP2_02348 HuMAP2_03284 HuMAP2_06297 HuMAP2_06350 HuMAP2_06425 |
| SKA2 | HuMAP2_00554 HuMAP2_02348 HuMAP2_03284 HuMAP2_06297 HuMAP2_06350 |
| CCDC85B | HuMAP2_02348 HuMAP2_06425 HuMAP2_06738 |
| SKA1 | HuMAP2_00369 HuMAP2_00554 HuMAP2_02348 HuMAP2_03284 HuMAP2_06297 HuMAP2_06350 |
| RALYL | HuMAP2_00554 HuMAP2_02348 HuMAP2_03284 |