hu.MAP 2.0: Complex View
Human Protein Complex Map
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Complex: HuMAP2_02356
Confidence: Medium High
Proteins| Genename | Protein Name | Links |
|---|---|---|
| FCGR2A | Low affinity immunoglobulin gamma Fc region receptor II-a (IgG Fc receptor II-a) (CDw32) (Fc-gamma RII-a) (Fc-gamma-RIIa) (FcRII-a) (CD antigen CD32) | UniProt NCBI |
| FCGR2B | Low affinity immunoglobulin gamma Fc region receptor II-b (IgG Fc receptor II-b) (CDw32) (Fc-gamma RII-b) (Fc-gamma-RIIb) (FcRII-b) (CD antigen CD32) | UniProt NCBI |
| FCGR2C | Low affinity immunoglobulin gamma Fc region receptor II-c (IgG Fc receptor II-c) (CDw32) (Fc-gamma RII-c) (Fc-gamma-RIIc) (FcRII-c) (CD antigen CD32) | UniProt NCBI |
| MTTP | Microsomal triglyceride transfer protein large subunit | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| HP:0025300 | 0.00039764290247 | 0.666666666667 | FCGR2B FCGR2A | Malar rash |
| HP:0003613 | 0.000803978270478 | 0.666666666667 | FCGR2B FCGR2A | Antiphospholipid antibody positivity |
| KEGG:05150 | 0.000957859912631 | 0.666666666667 | FCGR2B FCGR2A | Staphylococcus aureus infection |
| HP:0002102 | 0.0015104340107 | 0.666666666667 | FCGR2B FCGR2A | Pleuritis |
| KEGG:04666 | 0.0017077231529 | 0.666666666667 | FCGR2B FCGR2A | Fc gamma R-mediated phagocytosis |
| HP:0002725 | 0.00223433522771 | 0.666666666667 | FCGR2B FCGR2A | Systemic lupus erythematosus |
| KEGG:04380 | 0.00234185543972 | 0.666666666667 | FCGR2B FCGR2A | Osteoclast differentiation |
| HP:0003493 | 0.00243734739233 | 0.666666666667 | FCGR2B FCGR2A | Antinuclear antibody positivity |
| HP:0001701 | 0.00309925335629 | 0.666666666667 | FCGR2B FCGR2A | Pericarditis |
| KEGG:04145 | 0.00402657539006 | 0.666666666667 | FCGR2B FCGR2A | Phagosome |
| HP:0045073 | 0.00437859029972 | 0.666666666667 | FCGR2B FCGR2A | Serositis |
| HP:0030057 | 0.00466087105439 | 0.666666666667 | FCGR2B FCGR2A | Autoimmune antibody positivity |
| KEGG:05152 | 0.00497142990217 | 0.666666666667 | FCGR2B FCGR2A | Tuberculosis |
| HP:0000123 | 0.0068832170429 | 0.666666666667 | FCGR2B FCGR2A | Nephritis |
| HP:0001877 | 0.0100758259595 | 1.0 | MTTP FCGR2B FCGR2A | Abnormal erythrocyte morphology |
| HP:0001697 | 0.0116951722183 | 0.666666666667 | FCGR2B FCGR2A | Abnormal pericardium morphology |
| HP:0002103 | 0.0183346678183 | 0.666666666667 | FCGR2B FCGR2A | Abnormality of the pleura |
| HP:0000992 | 0.0244499336669 | 0.666666666667 | FCGR2B FCGR2A | Cutaneous photosensitivity |
| HP:0000709 | 0.0278358341925 | 0.666666666667 | FCGR2B FCGR2A | Psychosis |
| HP:0000988 | 0.0337079994886 | 0.666666666667 | FCGR2B FCGR2A | Skin rash |
| HP:0001878 | 0.0462248590062 | 0.666666666667 | FCGR2B FCGR2A | Hemolytic anemia |
| HP:0011895 | 0.0462248590062 | 0.666666666667 | FCGR2B FCGR2A | Anemia due to reduced life span of red cells |
Edges
| Protein 1 | Protein 2 | Score | Precision | Evidence |
|---|---|---|---|---|
| FCGR2A | FCGR2C | 0.959 | 0.863 | bioplex (FCGR2A) bioplex_WMM |
| FCGR2B | FCGR2A | 0.89 | 0.818 | bioplex (FCGR2B) bioplex_WMM |
| FCGR2A | MTTP | 0.118 | 0.391 | bioplex (FCGR2A) bioplex_WMM |
| FCGR2C | MTTP | 0.009 | 0.095 | bioplex_WMM WMM_only |
Images
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Complex HuMAP2_02356 has an average edge precision of 0.542 which is ranked 2257 out of all 6965 complexes.
Related Complexes
| Genename | Complexes |
|---|---|
| FCGR2A | HuMAP2_00204 HuMAP2_01158 HuMAP2_02356 |
| FCGR2B | HuMAP2_00204 HuMAP2_01158 HuMAP2_02356 |
| FCGR2C | HuMAP2_00204 HuMAP2_01158 HuMAP2_02356 |
| MTTP | HuMAP2_00204 HuMAP2_02356 |