hu.MAP 2.0: Complex View
Human Protein Complex Map
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Complex: HuMAP2_02390
Confidence: Very High
Proteins| Genename | Protein Name | Links |
|---|---|---|
| DYNC2H1 | Cytoplasmic dynein 2 heavy chain 1 (Cytoplasmic dynein 2 heavy chain) (Dynein cytoplasmic heavy chain 2) (Dynein heavy chain 11) (hDHC11) (Dynein heavy chain isotype 1B) | UniProt NCBI |
| DYNC2LI1 | Cytoplasmic dynein 2 light intermediate chain 1 (Dynein 2 light intermediate chain) | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| CORUM:6236 | 0.000110610948517 | 1.0 | DYNC2LI1 DYNC2H1 | Dynein-2 complex, cytoplasmic |
| KEGG:04962 | 0.000113800084426 | 1.0 | DYNC2LI1 DYNC2H1 | Vasopressin-regulated water reabsorption |
| WP:WP4532 | 0.000130776047433 | 1.0 | DYNC2LI1 DYNC2H1 | Intraflagellar transport proteins binding to dynein |
| HP:0000888 | 0.000303888373596 | 1.0 | DYNC2LI1 DYNC2H1 | Horizontal ribs |
| WP:WP4536 | 0.00195716973551 | 1.0 | DYNC2LI1 DYNC2H1 | Genes related to primary cilium development (based on CRISPR) |
| HP:0000090 | 0.00210384258643 | 1.0 | DYNC2LI1 DYNC2H1 | Nephronophthisis |
| REAC:R-HSA-5620924 | 0.00213680241453 | 1.0 | DYNC2LI1 DYNC2H1 | Intraflagellar transport |
| HP:0010306 | 0.00287525153479 | 1.0 | DYNC2LI1 DYNC2H1 | Short thorax |
| HP:0100957 | 0.00315910331233 | 1.0 | DYNC2LI1 DYNC2H1 | Abnormal renal medulla morphology |
| HP:0001830 | 0.00330603835011 | 1.0 | DYNC2LI1 DYNC2H1 | Postaxial foot polydactyly |
| HP:0000773 | 0.00460173822874 | 1.0 | DYNC2LI1 DYNC2H1 | Short ribs |
| HP:0010579 | 0.00611116179869 | 1.0 | DYNC2LI1 DYNC2H1 | Cone-shaped epiphysis |
| HP:0010322 | 0.00652191201795 | 1.0 | DYNC2LI1 DYNC2H1 | Abnormality of the 5th toe |
| HP:0000142 | 0.00877602907484 | 1.0 | DYNC2LI1 DYNC2H1 | Abnormal vagina morphology |
| HP:0008873 | 0.0113640893994 | 1.0 | DYNC2LI1 DYNC2H1 | Disproportionate short-limb short stature |
| HP:0006712 | 0.0119217746565 | 1.0 | DYNC2LI1 DYNC2H1 | Aplasia/Hypoplasia of the ribs |
| HP:0001162 | 0.0124928176442 | 1.0 | DYNC2LI1 DYNC2H1 | Postaxial hand polydactyly |
| HP:0000112 | 0.0124928176442 | 1.0 | DYNC2LI1 DYNC2H1 | Nephropathy |
| HP:0002983 | 0.0145966602306 | 1.0 | DYNC2LI1 DYNC2H1 | Micromelia |
| HP:0000889 | 0.0149105669023 | 1.0 | DYNC2LI1 DYNC2H1 | Abnormality of the clavicle |
| HP:0000774 | 0.0152278130066 | 1.0 | DYNC2LI1 DYNC2H1 | Narrow chest |
| HP:0001829 | 0.0155483985436 | 1.0 | DYNC2LI1 DYNC2H1 | Foot polydactyly |
| HP:0001773 | 0.0155483985436 | 1.0 | DYNC2LI1 DYNC2H1 | Short foot |
| HP:0009136 | 0.0168641350182 | 1.0 | DYNC2LI1 DYNC2H1 | Duplication involving bones of the feet |
| HP:0003498 | 0.0172014177186 | 1.0 | DYNC2LI1 DYNC2H1 | Disproportionate short stature |
| HP:0005257 | 0.0200198988979 | 1.0 | DYNC2LI1 DYNC2H1 | Thoracic hypoplasia |
| HP:0100259 | 0.0222740159548 | 1.0 | DYNC2LI1 DYNC2H1 | Postaxial polydactyly |
| HP:0006703 | 0.024648352588 | 1.0 | DYNC2LI1 DYNC2H1 | Aplasia/Hypoplasia of the lungs |
| GO:0035721 | 0.0247952876258 | 1.0 | DYNC2LI1 DYNC2H1 | intraciliary retrograde transport |
| HP:0006711 | 0.0280011429956 | 1.0 | DYNC2LI1 DYNC2H1 | Aplasia/Hypoplasia involving bones of the thorax |
| REAC:R-HSA-5617833 | 0.0304096312248 | 1.0 | DYNC2LI1 DYNC2H1 | Cilium Assembly |
| HP:0002652 | 0.0348636771466 | 1.0 | DYNC2LI1 DYNC2H1 | Skeletal dysplasia |
| HP:0002979 | 0.0358354520556 | 1.0 | DYNC2LI1 DYNC2H1 | Bowing of the legs |
| HP:0001161 | 0.0383233293999 | 1.0 | DYNC2LI1 DYNC2H1 | Hand polydactyly |
| HP:0000944 | 0.0451825241182 | 1.0 | DYNC2LI1 DYNC2H1 | Abnormality of the metaphysis |
| HP:0001770 | 0.0457335305099 | 1.0 | DYNC2LI1 DYNC2H1 | Toe syndactyly |
Edges
| Protein 1 | Protein 2 | Score | Precision | Evidence |
|---|---|---|---|---|
| DYNC2LI1 | DYNC2H1 | 0.988 | 0.901 | hein_WMM bioplex (DYNC2LI1) bioplex_WMM boldt (DYNC2LI1) boldt_WMM |
Images
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Complex HuMAP2_02390 has an average edge precision of 0.901 which is ranked 546 out of all 6965 complexes.
Related Complexes
| Genename | Complexes |
|---|---|
| DYNC2H1 | HuMAP2_01708 HuMAP2_02390 |
| DYNC2LI1 | HuMAP2_01708 HuMAP2_02390 |