hu.MAP 2.0: Complex View
Human Protein Complex Map
Search for a protein
Complex: HuMAP2_02393
Confidence: Medium
Proteins| Genename | Protein Name | Links |
|---|---|---|
| SLC1A5 | Neutral amino acid transporter B(0) (ATB(0)) (Baboon M7 virus receptor) (RD114/simian type D retrovirus receptor) (Sodium-dependent neutral amino acid transporter type 2) (Solute carrier family 1 member 5) | UniProt NCBI |
| TMCO1 | Calcium load-activated calcium channel (CLAC channel) (Transmembrane and coiled-coil domain-containing protein 1) (Transmembrane and coiled-coil domains protein 4) (Xenogeneic cross-immune protein PCIA3) | UniProt NCBI |
| SLC35F6 | Solute carrier family 35 member F6 (ANT2-binding protein) (ANT2BP) (Transport and Golgi organization 9 homolog) | UniProt NCBI |
| SLC35E1 | Solute carrier family 35 member E1 | UniProt NCBI |
| ATP2A2 | Sarcoplasmic/endoplasmic reticulum calcium ATPase 2 (SERCA2) (SR Ca(2+)-ATPase 2) (EC 7.2.2.10) (Calcium pump 2) (Calcium-transporting ATPase sarcoplasmic reticulum type, slow twitch skeletal muscle isoform) (Endoplasmic reticulum class 1/2 Ca(2+) ATPase) | UniProt NCBI |
| ATP1A1 | Sodium/potassium-transporting ATPase subunit alpha-1 (Na(+)/K(+) ATPase alpha-1 subunit) (EC 7.2.2.13) (Sodium pump subunit alpha-1) | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| MIRNA:hsa-miR-6746-3p | 0.0127972830278 | 0.333333333333 | SLC35F6 SLC1A5 | hsa-miR-6746-3p |
| MIRNA:hsa-miR-6741-3p | 0.014364358452 | 0.5 | TMCO1 SLC35E1 SLC1A5 | hsa-miR-6741-3p |
| MIRNA:hsa-miR-1226-3p | 0.0147886146912 | 0.5 | ATP2A2 SLC35F6 SLC1A5 | hsa-miR-1226-3p |
| KEGG:04974 | 0.0171495874594 | 0.333333333333 | ATP1A1 SLC1A5 | Protein digestion and absorption |
| KEGG:04260 | 0.0176099294651 | 0.333333333333 | ATP1A1 ATP2A2 | Cardiac muscle contraction |
| KEGG:04972 | 0.0200017533138 | 0.333333333333 | ATP1A1 ATP2A2 | Pancreatic secretion |
| REAC:R-HSA-5578775 | 0.0217814503669 | 0.333333333333 | ATP1A1 ATP2A2 | Ion homeostasis |
| REAC:R-HSA-936837 | 0.0237750563765 | 0.333333333333 | ATP1A1 ATP2A2 | Ion transport by P-type ATPases |
| CORUM:6507 | 0.0249904952816 | 0.166666666667 | ATP2A2 | SERCA-PLN complex |
| CORUM:6516 | 0.0249904952816 | 0.166666666667 | ATP2A2 | SLN-PLN-SERCA2A complex |
| MIRNA:hsa-miR-2681-3p | 0.0306365064944 | 0.333333333333 | TMCO1 SLC1A5 | hsa-miR-2681-3p |
| KEGG:04919 | 0.0388413362769 | 0.333333333333 | ATP1A1 ATP2A2 | Thyroid hormone signaling pathway |
| CORUM:6510 | 0.0499726005494 | 0.166666666667 | ATP2A2 | ILK-SERCA2A-PLN complex |
Edges
| Protein 1 | Protein 2 | Score | Precision | Evidence |
|---|---|---|---|---|
| ATP1A1 | ATP2A2 | 0.736 | 0.738 | hein_WMM bioplex_WMM boldt gupta_WMM fraction boldt_WMM treiber_WMM |
| SLC1A5 | ATP2A2 | 0.146 | 0.408 | hein_WMM bioplex (SLC1A5) bioplex_WMM boldt hein (ATP2A2) gupta_WMM boldt_WMM |
| TMCO1 | ATP2A2 | 0.09 | 0.354 | hein_WMM bioplex_WMM boldt hein (ATP2A2) gupta_WMM boldt_WMM |
| SLC35E1 | ATP2A2 | 0.037 | 0.264 | hein_WMM bioplex_WMM boldt hein (ATP2A2) gupta_WMM boldt_WMM |
| SLC35F6 | ATP2A2 | 0.026 | 0.224 | hein_WMM bioplex_WMM boldt hein (ATP2A2) boldt_WMM |
| TMCO1 | SLC1A5 | 0.013 | 0.148 | hein_WMM bioplex (SLC1A5) bioplex_WMM boldt gupta_WMM boldt_WMM |
| ATP1A1 | SLC1A5 | 0.01 | 0.12 | hein_WMM bioplex (SLC1A5) bioplex_WMM boldt gupta_WMM boldt_WMM treiber_WMM |
| ATP1A1 | TMCO1 | 0.009 | 0.098 | hein_WMM bioplex_WMM Guru boldt youn_WMM gupta_WMM fraction boldt_WMM |
| SLC35E1 | SLC35F6 | 0.008 | 0.013 | hein_WMM bioplex_WMM boldt boldt_WMM |
| ATP1A1 | SLC35F6 | 0.007 | 0.004 | hein_WMM bioplex_WMM boldt youn_WMM boldt_WMM |
| TMCO1 | SLC35F6 | 0.006 | 0.008 | hein_WMM bioplex_WMM boldt youn_WMM boldt_WMM |
| SLC35F6 | SLC1A5 | 0.006 | 0.005 | hein_WMM bioplex_WMM boldt boldt_WMM |
| SLC35E1 | SLC1A5 | 0.006 | 0.003 | hein_WMM bioplex (SLC1A5) bioplex_WMM boldt gupta_WMM boldt_WMM |
| ATP1A1 | SLC35E1 | 0.005 | 0.005 | hein_WMM bioplex_WMM boldt gupta_WMM boldt_WMM |
| TMCO1 | SLC35E1 | 0.0 | 0.008 | hein_WMM bioplex_WMM boldt gupta_WMM boldt_WMM |
Images
Click to enlarge
Complex HuMAP2_02393 has an average edge precision of 0.16 which is ranked 6629 out of all 6965 complexes.
Related Complexes
| Genename | Complexes |
|---|---|
| SLC1A5 | HuMAP2_02393 HuMAP2_02541 HuMAP2_05501 |
| TMCO1 | HuMAP2_01892 HuMAP2_02393 HuMAP2_06798 |
| SLC35F6 | HuMAP2_02393 HuMAP2_02541 |
| SLC35E1 | HuMAP2_02393 HuMAP2_02541 |
| ATP2A2 | HuMAP2_02393 HuMAP2_02541 HuMAP2_04352 HuMAP2_05501 |
| ATP1A1 | HuMAP2_00221 HuMAP2_02063 HuMAP2_02393 HuMAP2_04352 HuMAP2_05949 |