hu.MAP 2.0: Complex View
Human Protein Complex Map
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Complex: HuMAP2_02394
Confidence: Medium High
Proteins| Genename | Protein Name | Links |
|---|---|---|
| PDCD6IP | Programmed cell death 6-interacting protein (PDCD6-interacting protein) (ALG-2-interacting protein 1) (ALG-2-interacting protein X) (Hp95) | UniProt NCBI |
| MIF | Macrophage migration inhibitory factor (MIF) (EC 5.3.2.1) (Glycosylation-inhibiting factor) (GIF) (L-dopachrome isomerase) (L-dopachrome tautomerase) (EC 5.3.3.12) (Phenylpyruvate tautomerase) | UniProt NCBI |
| OXCT1 | Succinyl-CoA:3-ketoacid coenzyme A transferase 1, mitochondrial (EC 2.8.3.5) (3-oxoacid CoA-transferase 1) (Somatic-type succinyl-CoA:3-oxoacid CoA-transferase) (SCOT-s) | UniProt NCBI |
| GPT2 | Alanine aminotransferase 2 (ALT2) (EC 2.6.1.2) (Glutamate pyruvate transaminase 2) (GPT 2) (Glutamic--alanine transaminase 2) (Glutamic--pyruvic transaminase 2) | UniProt NCBI |
| KHNYN | Protein KHNYN (KH and NYN domain-containing protein) | UniProt NCBI |
| CAT | Catalase (EC 1.11.1.6) | UniProt NCBI |
| TKT | Transketolase (TK) (EC 2.2.1.1) | UniProt NCBI |
| RAB10 | Ras-related protein Rab-10 | UniProt NCBI |
| ETFA | Electron transfer flavoprotein subunit alpha, mitochondrial (Alpha-ETF) | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| KEGG:01200 | 0.00181556803409 | 0.333333333333 | CAT GPT2 TKT | Carbon metabolism |
| KEGG:01100 | 0.0226737535284 | 0.555555555556 | GPT2 CAT OXCT1 MIF TKT | Metabolic pathways |
| KEGG:01230 | 0.0403966480843 | 0.222222222222 | TKT GPT2 | Biosynthesis of amino acids |
Edges
| Protein 1 | Protein 2 | Score | Precision | Evidence |
|---|---|---|---|---|
| TKT | GPT2 | 0.873 | 0.805 | fraction treiber_WMM |
| TKT | ETFA | 0.557 | 0.648 | bioplex (ETFA,TKT) bioplex_WMM Guru youn_WMM fraction boldt_WMM |
| PDCD6IP | ETFA | 0.382 | 0.55 | bioplex (ETFA) bioplex_WMM youn_WMM gupta_WMM fraction |
| TKT | KHNYN | 0.351 | 0.537 | bioplex (TKT) bioplex_WMM youn_WMM |
| ETFA | MIF | 0.295 | 0.496 | bioplex_WMM youn_WMM gupta_WMM fraction boldt_WMM |
| CAT | ETFA | 0.26 | 0.482 | bioplex_WMM Guru boldt fraction boldt_WMM |
| PDCD6IP | TKT | 0.187 | 0.44 | bioplex (TKT) bioplex_WMM youn_WMM gupta_WMM fraction boldt_WMM treiber_WMM |
| ETFA | OXCT1 | 0.18 | 0.437 | bioplex_WMM youn_WMM gupta_WMM fraction treiber_WMM |
| ETFA | GPT2 | 0.115 | 0.383 | fraction treiber_WMM |
| CAT | GPT2 | 0.112 | 0.381 | fraction |
| TKT | RAB10 | 0.106 | 0.373 | bioplex_WMM boldt youn_WMM gupta_WMM fraction boldt_WMM treiber_WMM |
| CAT | OXCT1 | 0.06 | 0.336 | bioplex_WMM fraction treiber_WMM |
| TKT | MIF | 0.047 | 0.291 | bioplex_WMM boldt youn_WMM gupta_WMM fraction boldt_WMM treiber_WMM |
| PDCD6IP | GPT2 | 0.045 | 0.285 | fraction treiber_WMM |
| CAT | TKT | 0.01 | 0.129 | bioplex_WMM Guru boldt fraction boldt_WMM treiber_WMM |
| PDCD6IP | RAB10 | 0.007 | 0.008 | bioplex_WMM youn_WMM gupta_WMM WMM_only boldt_WMM |
| KHNYN | ETFA | 0.007 | 0.007 | youn_WMM WMM_only |
| TKT | OXCT1 | 0.007 | 0.002 | bioplex_WMM fraction treiber_WMM |
| PDCD6IP | KHNYN | 0.007 | 0.003 | youn_WMM WMM_only |
| MIF | RAB10 | 0.007 | 0.001 | bioplex_WMM boldt youn_WMM gupta_WMM boldt_WMM treiber_WMM |
| KHNYN | RAB10 | 0.007 | 0.006 | youn_WMM WMM_only |
| KHNYN | MIF | 0.007 | 0.001 | youn_WMM WMM_only |
| OXCT1 | GPT2 | 0.006 | 0.007 | fraction |
| ETFA | RAB10 | 0.003 | 0.01 | bioplex_WMM boldt youn_WMM gupta_WMM fraction boldt_WMM treiber_WMM |
| CAT | RAB10 | 0.003 | 0.02 | bioplex_WMM boldt fraction boldt_WMM treiber_WMM |
| MIF | OXCT1 | 0.0 | 0.016 | fraction |
| CAT | PDCD6IP | 0.0 | 0.011 | bioplex_WMM fraction boldt_WMM treiber_WMM |
| CAT | MIF | 0.0 | 0.014 | bioplex_WMM boldt fraction boldt_WMM |
| OXCT1 | RAB10 | 0.0 | 0.001 | bioplex_WMM gupta_WMM fraction |
| PDCD6IP | OXCT1 | 0.0 | 0.002 | bioplex_WMM youn_WMM gupta_WMM fraction |
| PDCD6IP | MIF | 0.0 | 0.001 | bioplex_WMM youn_WMM gupta_WMM fraction |
Images
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Complex HuMAP2_02394 has an average edge precision of 0.216 which is ranked 5937 out of all 6965 complexes.
Related Complexes