hu.MAP 2.0: Complex View
Human Protein Complex Map
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Complex: HuMAP2_02414
Confidence: Medium
Proteins| Genename | Protein Name | Links |
|---|---|---|
| CHTOP | Chromatin target of PRMT1 protein (Friend of PRMT1 protein) (Small arginine- and glycine-rich protein) (SRAG) | UniProt NCBI |
| PRMT1 | Protein arginine N-methyltransferase 1 (EC 2.1.1.319) (Histone-arginine N-methyltransferase PRMT1) (Interferon receptor 1-bound protein 4) | UniProt NCBI |
| PRMT8 | Protein arginine N-methyltransferase 8 (EC 2.1.1.319) (EC 2.1.1.321) (Heterogeneous nuclear ribonucleoprotein methyltransferase-like protein 4) | UniProt NCBI |
| ABCF2 | ATP-binding cassette sub-family F member 2 (Iron-inhibited ABC transporter 2) | UniProt NCBI |
| ANGEL2 | Protein angel homolog 2 | UniProt NCBI |
| CAD | CAD protein [Includes: Glutamine-dependent carbamoyl-phosphate synthase (EC 6.3.5.5); Aspartate carbamoyltransferase (EC 2.1.3.2); Dihydroorotase (EC 3.5.2.3)] | UniProt NCBI |
| LRRC45 | Leucine-rich repeat-containing protein 45 | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| CORUM:6858 | 8.38550741504e-05 | 0.333333333333 | CHTOP PRMT1 | CHTOP-methylosome complex |
| CORUM:1731 | 0.0249904952816 | 0.166666666667 | PRMT1 | PRMT1 complex |
| CORUM:2765 | 0.0249904952816 | 0.166666666667 | PRMT1 | PRMT1 complex |
| GO:0035241 | 0.0405595771497 | 0.333333333333 | PRMT8 PRMT1 | protein-arginine omega-N monomethyltransferase activity |
| GO:0035242 | 0.0405595771497 | 0.333333333333 | PRMT8 PRMT1 | protein-arginine omega-N asymmetric methyltransferase activity |
Edges
| Protein 1 | Protein 2 | Score | Precision | Evidence |
|---|---|---|---|---|
| PRMT1 | PRMT8 | 0.867 | 0.801 | bioplex (PRMT8) bioplex_WMM |
| CHTOP | PRMT8 | 0.102 | 0.365 | bioplex (PRMT8) bioplex_WMM |
| PRMT1 | ABCF2 | 0.048 | 0.295 | bioplex (ABCF2) youn_WMM gupta_WMM fraction treiber_WMM |
| PRMT8 | LRRC45 | 0.028 | 0.233 | bioplex (PRMT8) bioplex_WMM |
| CAD | ABCF2 | 0.025 | 0.21 | hein_WMM bioplex (ABCF2) bioplex_WMM Guru fraction treiber_WMM |
| PRMT8 | ANGEL2 | 0.023 | 0.208 | bioplex (PRMT8) bioplex_WMM |
| PRMT1 | ANGEL2 | 0.009 | 0.094 | bioplex_WMM youn_WMM WMM_only |
| PRMT1 | LRRC45 | 0.008 | 0.027 | bioplex (LRRC45) bioplex_WMM |
| ANGEL2 | LRRC45 | 0.008 | 0.01 | bioplex_WMM WMM_only |
| CHTOP | LRRC45 | 0.007 | 0.005 | bioplex_WMM WMM_only |
| PRMT1 | CHTOP | 0.007 | 0.008 | hein_WMM bioplex_WMM youn_WMM gupta_WMM WMM_only |
| CAD | CHTOP | 0.007 | 0.005 | bioplex_WMM WMM_only |
| ABCF2 | ANGEL2 | 0.007 | 0.003 | youn_WMM WMM_only |
| CAD | ANGEL2 | 0.007 | 0.002 | bioplex_WMM WMM_only |
| CHTOP | ANGEL2 | 0.007 | 0.002 | bioplex_WMM youn_WMM WMM_only |
| ABCF2 | CHTOP | 0.0 | 0.012 | bioplex_WMM youn_WMM gupta_WMM fraction |
| CAD | PRMT1 | 0.0 | 0.001 | boldt fraction boldt_WMM treiber_WMM |
Images
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Complex HuMAP2_02414 has an average edge precision of 0.134 which is ranked 6809 out of all 6965 complexes.
Related Complexes
| Genename | Complexes |
|---|---|
| CHTOP | HuMAP2_01249 HuMAP2_02061 HuMAP2_02414 HuMAP2_05884 HuMAP2_06223 |
| PRMT1 | HuMAP2_01159 HuMAP2_02414 HuMAP2_04633 HuMAP2_05164 HuMAP2_06370 |
| PRMT8 | HuMAP2_02414 HuMAP2_04633 HuMAP2_05164 |
| ABCF2 | HuMAP2_01159 HuMAP2_02414 HuMAP2_06370 |
| ANGEL2 | HuMAP2_02414 HuMAP2_04633 |
| CAD | HuMAP2_00368 HuMAP2_01301 HuMAP2_02414 HuMAP2_05612 |
| LRRC45 | HuMAP2_02414 HuMAP2_04633 |