hu.MAP 2.0: Complex View
Human Protein Complex Map
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Complex: HuMAP2_02427
Confidence: Medium High
Proteins| Genename | Protein Name | Links |
|---|---|---|
| DPYSL3 | Dihydropyrimidinase-related protein 3 (DRP-3) (Collapsin response mediator protein 4) (CRMP-4) (Unc-33-like phosphoprotein 1) (ULIP-1) | UniProt NCBI |
| DPYSL5 | Dihydropyrimidinase-related protein 5 (DRP-5) (CRMP3-associated molecule) (CRAM) (Collapsin response mediator protein 5) (CRMP-5) (UNC33-like phosphoprotein 6) (ULIP-6) | UniProt NCBI |
| DPYSL4 | Dihydropyrimidinase-related protein 4 (DRP-4) (Collapsin response mediator protein 3) (CRMP-3) (UNC33-like phosphoprotein 4) (ULIP-4) | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| REAC:R-HSA-399956 | 2.51774270163e-07 | 1.0 | DPYSL4 DPYSL5 DPYSL3 | CRMPs in Sema3A signaling |
| GO:0016812 | 7.62876038594e-06 | 1.0 | DPYSL4 DPYSL5 DPYSL3 | hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides |
| REAC:R-HSA-373755 | 1.46159459799e-05 | 1.0 | DPYSL4 DPYSL5 DPYSL3 | Semaphorin interactions |
| REAC:R-HSA-422475 | 0.0100572742862 | 1.0 | DPYSL4 DPYSL5 DPYSL3 | Axon guidance |
| GO:0016810 | 0.0142448028307 | 1.0 | DPYSL4 DPYSL5 DPYSL3 | hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds |
Edges
| Protein 1 | Protein 2 | Score | Precision | Evidence |
|---|---|---|---|---|
| DPYSL5 | DPYSL4 | 0.831 | 0.778 | bioplex (DPYSL5) bioplex_WMM youn_WMM gupta_WMM |
| DPYSL5 | DPYSL3 | 0.249 | 0.472 | bioplex (DPYSL3,DPYSL5) bioplex_WMM youn_WMM gupta_WMM |
| DPYSL3 | DPYSL4 | 0.214 | 0.464 | bioplex (DPYSL3) bioplex_WMM youn_WMM gupta_WMM |
Images
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Complex HuMAP2_02427 has an average edge precision of 0.571 which is ranked 2072 out of all 6965 complexes.
Related Complexes
| Genename | Complexes |
|---|---|
| DPYSL3 | HuMAP2_00292 HuMAP2_02427 HuMAP2_05645 HuMAP2_06701 |
| DPYSL5 | HuMAP2_00292 HuMAP2_02285 HuMAP2_02427 HuMAP2_03430 |
| DPYSL4 | HuMAP2_00292 HuMAP2_02427 HuMAP2_03430 |