hu.MAP 2.0: Complex View
Human Protein Complex Map
Search for a protein
Complex: HuMAP2_02428
Confidence: Medium High
Proteins| Genename | Protein Name | Links |
|---|---|---|
| URI1 | Unconventional prefoldin RPB5 interactor 1 (Protein NNX3) (Protein phosphatase 1 regulatory subunit 19) (RNA polymerase II subunit 5-mediating protein) (RPB5-mediating protein) | UniProt NCBI |
| PDRG1 | p53 and DNA damage-regulated protein 1 | UniProt NCBI |
| PFDN2 | Prefoldin subunit 2 | UniProt NCBI |
| PFDN5 | Prefoldin subunit 5 (Myc modulator 1) (c-Myc-binding protein Mm-1) | UniProt NCBI |
| PFDN6 | Prefoldin subunit 6 (Protein Ke2) | UniProt NCBI |
| PIH1D1 | PIH1 domain-containing protein 1 (Nucleolar protein 17 homolog) | UniProt NCBI |
| TIPARP | Protein mono-ADP-ribosyltransferase TIPARP (EC 2.4.2.-) (ADP-ribosyltransferase diphtheria toxin-like 14) (ARTD14) (Poly [ADP-ribose] polymerase 7) (PARP-7) (TCDD-inducible poly [ADP-ribose] polymerase) | UniProt NCBI |
| VBP1 | Prefoldin subunit 3 (HIBBJ46) (von Hippel-Lindau-binding protein 1) (VBP-1) (VHL-binding protein 1) | UniProt NCBI |
| UXT | Protein UXT (Androgen receptor trapped clone 27 protein) (ART-27) (Ubiquitously expressed transcript protein) | UniProt NCBI |
| PFDN4 | Prefoldin subunit 4 (Protein C-1) | UniProt NCBI |
| PFDN1 | Prefoldin subunit 1 | UniProt NCBI |
| MARCH9 | E3 ubiquitin-protein ligase MARCH9 (EC 2.3.2.27) (Membrane-associated RING finger protein 9) (Membrane-associated RING-CH protein IX) (MARCH-IX) (RING finger protein 179) (RING-type E3 ubiquitin transferase MARCH9) | UniProt NCBI |
| RPAP3 | RNA polymerase II-associated protein 3 | UniProt NCBI |
| WDR92 | WD repeat-containing protein 92 (WD repeat-containing protein Monad) | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| CORUM:112 | 1.05462805827e-17 | 0.428571428571 | PFDN4 PFDN1 PFDN5 VBP1 PFDN6 PFDN2 | Prefoldin complex |
| CORUM:33 | 1.05462805827e-17 | 0.428571428571 | PFDN4 PFDN1 PFDN5 VBP1 PFDN6 PFDN2 | Prefoldin complex |
| REAC:R-HSA-389957 | 1.47524348532e-11 | 0.428571428571 | PFDN4 PFDN1 PFDN5 VBP1 PFDN6 PFDN2 | Prefoldin mediated transfer of substrate to CCT/TriC |
| GO:0016272 | 1.64002397e-11 | 0.357142857143 | PFDN4 PFDN5 VBP1 PFDN6 PFDN2 | prefoldin complex |
| REAC:R-HSA-389958 | 3.66268637434e-11 | 0.428571428571 | PFDN4 PFDN1 PFDN5 VBP1 PFDN6 PFDN2 | Cooperation of Prefoldin and TriC/CCT in actin and tubulin folding |
| REAC:R-HSA-390466 | 3.01397516929e-08 | 0.428571428571 | PFDN4 PFDN1 PFDN5 VBP1 PFDN6 PFDN2 | Chaperonin-mediated protein folding |
| REAC:R-HSA-391251 | 4.47524839718e-08 | 0.428571428571 | PFDN4 PFDN1 PFDN5 VBP1 PFDN6 PFDN2 | Protein folding |
| HPA:002020_23 | 0.00106557235297 | 0.357142857143 | URI1 UXT PFDN4 PIH1D1 VBP1 | appendix; lymphoid tissue[Approved,High] |
| HPA:050020_23 | 0.00150788891717 | 0.357142857143 | URI1 UXT PFDN4 PIH1D1 VBP1 | spleen; cells in white pulp[Approved,High] |
| CORUM:781 | 0.0015652691283 | 0.142857142857 | URI1 PFDN2 | URI complex (Unconventional prefoldin RPB5 Interactor) |
| CORUM:5199 | 0.00519797849149 | 0.142857142857 | PDRG1 PFDN2 | Kinase maturation complex 1 |
| HPA:031010_22 | 0.00656073818368 | 0.5 | PFDN4 PFDN1 UXT URI1 PIH1D1 PFDN2 VBP1 | ovary; follicle cells[Approved,Medium] |
| HPA:031010_21 | 0.0101888063466 | 0.571428571429 | PFDN4 PDRG1 UXT PFDN1 URI1 VBP1 PFDN2 PIH1D1 | ovary; follicle cells[Approved,Low] |
| HPA:035020_22 | 0.0112595275225 | 0.714285714286 | PFDN1 PFDN4 PDRG1 URI1 WDR92 UXT PFDN5 VBP1 PFDN2 PIH1D1 | placenta; trophoblastic cells[Approved,Medium] |
| HPA:053020_22 | 0.016137291881 | 0.714285714286 | PFDN1 PFDN4 PDRG1 URI1 WDR92 UXT PFDN5 VBP1 PFDN2 PIH1D1 | testis; cells in seminiferous ducts[Approved,Medium] |
| HPA:056020_23 | 0.016414834735 | 0.357142857143 | URI1 UXT PFDN4 PIH1D1 VBP1 | tonsil; non-germinal center cells[Approved,High] |
| HPA:050020_22 | 0.0181619151747 | 0.5 | PFDN4 URI1 PFDN1 UXT PFDN5 PIH1D1 VBP1 | spleen; cells in white pulp[Approved,Medium] |
| HPA:011030_22 | 0.0186860528729 | 0.571428571429 | PFDN4 PDRG1 PFDN5 PFDN1 UXT WDR92 URI1 PFDN2 | colon; peripheral nerve/ganglion[Approved,Medium] |
| HPA:002010_22 | 0.0201068493258 | 0.714285714286 | PFDN1 PFDN4 PDRG1 URI1 WDR92 UXT PFDN5 VBP1 PFDN2 PIH1D1 | appendix; glandular cells[Approved,Medium] |
| HPA:041010_21 | 0.0243577178071 | 0.714285714286 | PFDN1 PFDN4 PDRG1 URI1 WDR92 UXT PFDN5 VBP1 PFDN2 PIH1D1 | skeletal muscle; myocytes[Approved,Low] |
| HPA:005010_22 | 0.0281963207431 | 0.714285714286 | PFDN1 PFDN4 PDRG1 URI1 WDR92 UXT PFDN5 VBP1 PFDN2 PIH1D1 | bronchus; respiratory epithelial cells[Approved,Medium] |
| HPA:022020_21 | 0.0336176114859 | 0.714285714286 | PFDN1 PFDN4 PDRG1 URI1 WDR92 UXT PFDN5 VBP1 PFDN2 PIH1D1 | hippocampus; neuronal cells[Approved,Low] |
| HPA:056030_22 | 0.036488710492 | 0.642857142857 | PFDN1 PFDN4 URI1 WDR92 UXT PFDN5 PIH1D1 PFDN2 VBP1 | tonsil; squamous epithelial cells[Approved,Medium] |
| HPA:052010_22 | 0.0394077844814 | 0.714285714286 | PFDN1 PFDN4 PDRG1 URI1 WDR92 UXT PFDN5 VBP1 PFDN2 PIH1D1 | stomach 2; glandular cells[Approved,Medium] |
| HPA:002020_22 | 0.0453226831079 | 0.5 | PFDN4 URI1 PFDN1 UXT PFDN5 PIH1D1 VBP1 | appendix; lymphoid tissue[Approved,Medium] |
| HPA:011010_22 | 0.0455445137168 | 0.571428571429 | PFDN4 PDRG1 URI1 WDR92 UXT PFDN5 PIH1D1 PFDN2 | colon; endothelial cells[Approved,Medium] |
| HPA:004020_22 | 0.0465135361851 | 0.642857142857 | PFDN4 PDRG1 URI1 UXT PFDN1 PFDN5 VBP1 PFDN2 PIH1D1 | breast; glandular cells[Approved,Medium] |
| HPA:028010_23 | 0.0480482579377 | 0.285714285714 | UXT PFDN4 PIH1D1 VBP1 | lymph node; germinal center cells[Approved,High] |
Edges
| Protein 1 | Protein 2 | Score | Precision | Evidence |
|---|---|---|---|---|
| VBP1 | PFDN4 | 1.0 | 0.949 | hein_WMM bioplex (PFDN4,VBP1) bioplex_WMM Guru boldt youn_WMM hein (VBP1) gupta_WMM fraction boldt_WMM |
| PFDN2 | PFDN5 | 1.0 | 0.949 | hein_WMM bioplex (PFDN2) bioplex_WMM Guru boldt youn_WMM hein (PFDN2) gupta_WMM fraction boldt_WMM |
| PIH1D1 | RPAP3 | 1.0 | 0.949 | hein_WMM bioplex (PIH1D1) bioplex_WMM boldt youn_WMM Malo gupta_WMM fraction boldt_WMM |
| PFDN2 | PFDN1 | 1.0 | 0.949 | hein_WMM bioplex (PFDN2) bioplex_WMM Guru boldt youn_WMM hein (PFDN2) gupta_WMM fraction boldt_WMM |
| PFDN2 | VBP1 | 1.0 | 0.949 | hein_WMM bioplex (PFDN2,VBP1) bioplex_WMM Guru boldt youn_WMM hein (PFDN2,VBP1) gupta_WMM fraction boldt_WMM |
| PFDN2 | PFDN6 | 1.0 | 0.949 | hein_WMM bioplex (PFDN2) bioplex_WMM Guru boldt youn_WMM hein (PFDN2) Malo gupta_WMM fraction boldt_WMM |
| VBP1 | PFDN5 | 1.0 | 0.949 | hein_WMM bioplex (VBP1) bioplex_WMM Guru boldt youn_WMM hein (VBP1) gupta_WMM fraction boldt_WMM |
| VBP1 | PFDN1 | 1.0 | 0.949 | hein_WMM bioplex (VBP1) bioplex_WMM Guru boldt youn_WMM hein (VBP1) gupta_WMM fraction boldt_WMM |
| PFDN4 | PFDN6 | 1.0 | 0.949 | hein_WMM bioplex (PFDN4) bioplex_WMM Guru boldt youn_WMM gupta_WMM fraction boldt_WMM |
| VBP1 | PFDN6 | 1.0 | 0.949 | hein_WMM bioplex (VBP1) bioplex_WMM Guru boldt youn_WMM hein (VBP1) gupta_WMM fraction boldt_WMM |
| PFDN2 | PFDN4 | 1.0 | 0.949 | hein_WMM bioplex (PFDN2,PFDN4) bioplex_WMM Guru boldt youn_WMM hein (PFDN2) gupta_WMM fraction boldt_WMM |
| PFDN4 | PFDN5 | 1.0 | 0.949 | hein_WMM bioplex (PFDN4) bioplex_WMM Guru boldt youn_WMM gupta_WMM fraction boldt_WMM |
| PFDN5 | PFDN6 | 1.0 | 0.949 | hein_WMM bioplex_WMM Guru boldt youn_WMM gupta_WMM fraction boldt_WMM |
| PFDN1 | PFDN5 | 1.0 | 0.949 | hein_WMM bioplex_WMM Guru boldt youn_WMM gupta_WMM fraction boldt_WMM |
| PIH1D1 | URI1 | 1.0 | 0.949 | hein_WMM bioplex (PIH1D1) bioplex_WMM boldt youn_WMM gupta_WMM boldt_WMM |
| WDR92 | PIH1D1 | 1.0 | 0.949 | hein_WMM bioplex (PIH1D1) bioplex_WMM boldt youn_WMM gupta_WMM boldt_WMM |
| RPAP3 | URI1 | 1.0 | 0.949 | hein_WMM bioplex_WMM boldt youn_WMM Malo gupta_WMM fraction boldt_WMM |
| WDR92 | RPAP3 | 1.0 | 0.949 | hein_WMM bioplex_WMM boldt youn_WMM Malo gupta_WMM fraction boldt_WMM |
| PFDN1 | PFDN6 | 1.0 | 0.949 | hein_WMM bioplex_WMM Guru boldt youn_WMM gupta_WMM fraction boldt_WMM |
| PIH1D1 | PDRG1 | 0.999 | 0.949 | hein_WMM bioplex (PIH1D1) bioplex_WMM boldt youn_WMM gupta_WMM boldt_WMM |
| PFDN4 | PFDN1 | 0.999 | 0.949 | hein_WMM bioplex (PFDN4) bioplex_WMM Guru boldt youn_WMM gupta_WMM fraction boldt_WMM |
| PIH1D1 | UXT | 0.999 | 0.946 | hein_WMM bioplex (PIH1D1,UXT) bioplex_WMM boldt youn_WMM gupta_WMM boldt_WMM |
| PDRG1 | URI1 | 0.998 | 0.944 | hein_WMM bioplex_WMM boldt youn_WMM Malo gupta_WMM fraction boldt_WMM |
| PFDN2 | WDR92 | 0.997 | 0.935 | hein_WMM bioplex (PFDN2,WDR92) bioplex_WMM boldt youn_WMM hein (PFDN2) Malo gupta_WMM fraction boldt_WMM |
| PFDN2 | PDRG1 | 0.996 | 0.929 | hein_WMM bioplex (PFDN2) bioplex_WMM boldt youn_WMM hein (PFDN2) gupta_WMM boldt_WMM |
| PFDN2 | URI1 | 0.965 | 0.874 | hein_WMM bioplex (PFDN2) bioplex_WMM boldt youn_WMM hein (PFDN2) gupta_WMM boldt_WMM |
| UXT | URI1 | 0.944 | 0.856 | hein_WMM bioplex (UXT) bioplex_WMM boldt youn_WMM gupta_WMM boldt_WMM |
| PFDN2 | PIH1D1 | 0.94 | 0.853 | hein_WMM bioplex (PFDN2,PIH1D1) bioplex_WMM boldt youn_WMM hein (PFDN2) gupta_WMM boldt_WMM |
| PDRG1 | UXT | 0.907 | 0.83 | hein_WMM bioplex (UXT) bioplex_WMM boldt youn_WMM gupta_WMM boldt_WMM |
| PFDN2 | RPAP3 | 0.856 | 0.793 | hein_WMM bioplex (PFDN2) bioplex_WMM boldt youn_WMM hein (PFDN2) gupta_WMM boldt_WMM |
| PFDN2 | UXT | 0.819 | 0.773 | hein_WMM bioplex (PFDN2,UXT) bioplex_WMM boldt youn_WMM hein (PFDN2) gupta_WMM boldt_WMM |
| WDR92 | UXT | 0.799 | 0.765 | hein_WMM bioplex (UXT) bioplex_WMM boldt youn_WMM gupta_WMM boldt_WMM |
| RPAP3 | UXT | 0.774 | 0.751 | hein_WMM bioplex (UXT) bioplex_WMM boldt youn_WMM gupta_WMM boldt_WMM |
| PDRG1 | VBP1 | 0.472 | 0.607 | hein_WMM bioplex (VBP1) bioplex_WMM youn_WMM hein (VBP1) gupta_WMM |
| PIH1D1 | PFDN6 | 0.173 | 0.433 | hein_WMM bioplex (PIH1D1) bioplex_WMM boldt youn_WMM gupta_WMM boldt_WMM |
| WDR92 | URI1 | 0.16 | 0.418 | hein_WMM bioplex_WMM boldt youn_WMM gupta_WMM boldt_WMM |
| PFDN4 | MARCH9 | 0.1 | 0.362 | bioplex (PFDN4) bioplex_WMM |
| PFDN2 | TIPARP | 0.051 | 0.296 | bioplex (PFDN2) bioplex_WMM youn_WMM |
| RPAP3 | PDRG1 | 0.033 | 0.246 | hein_WMM bioplex_WMM boldt youn_WMM gupta_WMM boldt_WMM |
| UXT | PFDN6 | 0.028 | 0.232 | hein_WMM bioplex (UXT) bioplex_WMM boldt youn_WMM gupta_WMM boldt_WMM |
| PDRG1 | PFDN6 | 0.027 | 0.223 | hein_WMM bioplex_WMM boldt youn_WMM gupta_WMM boldt_WMM |
| WDR92 | PDRG1 | 0.025 | 0.215 | hein_WMM bioplex_WMM boldt youn_WMM gupta_WMM boldt_WMM |
| PDRG1 | PFDN4 | 0.019 | 0.184 | hein_WMM bioplex (PFDN4) bioplex_WMM youn_WMM gupta_WMM |
| RPAP3 | PFDN6 | 0.016 | 0.16 | hein_WMM bioplex_WMM boldt youn_WMM gupta_WMM boldt_WMM |
| URI1 | PFDN6 | 0.014 | 0.144 | hein_WMM bioplex_WMM boldt youn_WMM gupta_WMM boldt_WMM |
| WDR92 | PFDN6 | 0.013 | 0.143 | hein_WMM bioplex (WDR92) bioplex_WMM boldt youn_WMM gupta_WMM boldt_WMM |
| PDRG1 | PFDN5 | 0.011 | 0.145 | hein_WMM bioplex_WMM youn_WMM gupta_WMM WMM_only |
| PDRG1 | PFDN1 | 0.009 | 0.095 | hein_WMM bioplex_WMM youn_WMM gupta_WMM WMM_only |
| TIPARP | RPAP3 | 0.008 | 0.033 | bioplex_WMM youn_WMM WMM_only |
| TIPARP | PFDN5 | 0.008 | 0.024 | bioplex_WMM youn_WMM WMM_only |
| TIPARP | URI1 | 0.008 | 0.024 | bioplex_WMM WMM_only |
| TIPARP | PDRG1 | 0.008 | 0.023 | bioplex_WMM WMM_only |
| TIPARP | VBP1 | 0.008 | 0.016 | bioplex_WMM youn_WMM WMM_only |
| TIPARP | PFDN1 | 0.008 | 0.016 | bioplex_WMM WMM_only |
| TIPARP | PIH1D1 | 0.007 | 0.008 | bioplex_WMM youn_WMM WMM_only |
| TIPARP | WDR92 | 0.007 | 0.009 | bioplex_WMM WMM_only |
| URI1 | MARCH9 | 0.007 | 0.005 | bioplex_WMM WMM_only |
| RPAP3 | PFDN5 | 0.007 | 0.008 | hein_WMM bioplex_WMM boldt youn_WMM gupta_WMM boldt_WMM |
| PFDN5 | MARCH9 | 0.007 | 0.004 | bioplex_WMM WMM_only |
| TIPARP | PFDN4 | 0.007 | 0.007 | bioplex_WMM WMM_only |
| TIPARP | PFDN6 | 0.007 | 0.013 | bioplex_WMM WMM_only |
| PDRG1 | MARCH9 | 0.007 | 0.012 | bioplex_WMM WMM_only |
| VBP1 | MARCH9 | 0.007 | 0.01 | bioplex_WMM WMM_only |
| PFDN1 | MARCH9 | 0.007 | 0.013 | bioplex_WMM WMM_only |
| RPAP3 | VBP1 | 0.007 | 0.011 | hein_WMM bioplex_WMM boldt youn_WMM gupta_WMM boldt_WMM |
| TIPARP | UXT | 0.007 | 0.008 | bioplex_WMM WMM_only |
| PIH1D1 | MARCH9 | 0.007 | 0.004 | bioplex_WMM WMM_only |
| URI1 | PFDN5 | 0.007 | 0.004 | hein_WMM bioplex_WMM boldt youn_WMM gupta_WMM boldt_WMM |
| PFDN6 | MARCH9 | 0.007 | 0.005 | bioplex_WMM WMM_only |
| PFDN2 | MARCH9 | 0.007 | 0.008 | bioplex (MARCH9) bioplex_WMM |
| UXT | MARCH9 | 0.007 | 0.008 | bioplex_WMM WMM_only |
| PIH1D1 | PFDN5 | 0.007 | 0.001 | hein_WMM bioplex_WMM boldt youn_WMM gupta_WMM boldt_WMM |
| URI1 | VBP1 | 0.007 | 0.003 | hein_WMM bioplex_WMM boldt youn_WMM gupta_WMM boldt_WMM |
| WDR92 | MARCH9 | 0.007 | 0.006 | bioplex_WMM WMM_only |
| RPAP3 | MARCH9 | 0.007 | 0.002 | bioplex_WMM WMM_only |
| RPAP3 | PFDN1 | 0.007 | 0.005 | hein_WMM bioplex_WMM boldt youn_WMM gupta_WMM boldt_WMM |
| URI1 | PFDN1 | 0.006 | 0.003 | hein_WMM bioplex_WMM boldt youn_WMM gupta_WMM boldt_WMM |
| UXT | PFDN5 | 0.006 | 0.004 | hein_WMM bioplex_WMM boldt youn_WMM gupta_WMM boldt_WMM |
| UXT | VBP1 | 0.006 | 0.004 | hein_WMM bioplex_WMM boldt youn_WMM gupta_WMM boldt_WMM |
| UXT | PFDN1 | 0.006 | 0.008 | hein_WMM bioplex_WMM youn_WMM gupta_WMM WMM_only |
| PIH1D1 | PFDN4 | 0.006 | 0.008 | hein_WMM bioplex (PFDN4,PIH1D1) bioplex_WMM boldt youn_WMM gupta_WMM boldt_WMM |
| PIH1D1 | VBP1 | 0.005 | 0.012 | hein_WMM bioplex (PIH1D1) bioplex_WMM boldt youn_WMM gupta_WMM boldt_WMM |
| RPAP3 | PFDN4 | 0.005 | 0.012 | hein_WMM bioplex (PFDN4) bioplex_WMM boldt youn_WMM gupta_WMM boldt_WMM |
| PIH1D1 | PFDN1 | 0.005 | 0.011 | hein_WMM bioplex (PIH1D1) bioplex_WMM boldt youn_WMM gupta_WMM boldt_WMM |
| URI1 | PFDN4 | 0.005 | 0.013 | hein_WMM bioplex (PFDN4) bioplex_WMM boldt youn_WMM gupta_WMM boldt_WMM |
| WDR92 | PFDN5 | 0.005 | 0.011 | hein_WMM bioplex (WDR92) bioplex_WMM boldt youn_WMM gupta_WMM boldt_WMM |
| WDR92 | PFDN1 | 0.005 | 0.012 | hein_WMM bioplex (WDR92) bioplex_WMM boldt youn_WMM gupta_WMM boldt_WMM |
| UXT | PFDN4 | 0.005 | 0.01 | hein_WMM bioplex (PFDN4) bioplex_WMM youn_WMM gupta_WMM |
| WDR92 | PFDN4 | 0.004 | 0.011 | hein_WMM bioplex (PFDN4) bioplex_WMM boldt youn_WMM gupta_WMM boldt_WMM |
| WDR92 | VBP1 | 0.0 | 0.001 | hein_WMM bioplex (VBP1,WDR92) bioplex_WMM boldt youn_WMM gupta_WMM fraction boldt_WMM |
Images
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Complex HuMAP2_02428 has an average edge precision of 0.383 which is ranked 3489 out of all 6965 complexes.
Related Complexes