hu.MAP 2.0: Complex View
Human Protein Complex Map
Search for a protein
Complex: HuMAP2_02430
Confidence: Medium High
Proteins| Genename | Protein Name | Links |
|---|---|---|
| TXNDC9 | Thioredoxin domain-containing protein 9 (ATP-binding protein associated with cell differentiation) (Protein 1-4) | UniProt NCBI |
| CYP27A1 | Sterol 26-hydroxylase, mitochondrial (EC 1.14.15.15) (5-beta-cholestane-3-alpha,7-alpha,12-alpha-triol 26-hydroxylase) (Cytochrome P-450C27/25) (Cytochrome P450 27) (Sterol 27-hydroxylase) (Vitamin D(3) 25-hydroxylase) | UniProt NCBI |
| CCT6B | T-complex protein 1 subunit zeta-2 (TCP-1-zeta-2) (CCT-zeta-2) (CCT-zeta-like) (TCP-1-zeta-like) (Testis-specific Tcp20) (Testis-specific protein TSA303) | UniProt NCBI |
| TUBAL3 | Tubulin alpha chain-like 3 | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| REAC:R-HSA-389960 | 0.00276986547413 | 0.5 | CCT6B TUBAL3 | Formation of tubulin folding intermediates by CCT/TriC |
| REAC:R-HSA-389958 | 0.00466369436644 | 0.5 | CCT6B TUBAL3 | Cooperation of Prefoldin and TriC/CCT in actin and tubulin folding |
| REAC:R-HSA-390466 | 0.0399558314157 | 0.5 | CCT6B TUBAL3 | Chaperonin-mediated protein folding |
| REAC:R-HSA-391251 | 0.0454682616856 | 0.5 | CCT6B TUBAL3 | Protein folding |
| REAC:R-HSA-5578996 | 0.0499190562503 | 0.25 | CYP27A1 | Defective CYP27A1 causes Cerebrotendinous xanthomatosis (CTX) |
Edges
| Protein 1 | Protein 2 | Score | Precision | Evidence |
|---|---|---|---|---|
| TXNDC9 | CCT6B | 0.091 | 0.354 | bioplex (TXNDC9) bioplex_WMM Guru youn_WMM gupta_WMM fraction |
| CCT6B | CYP27A1 | 0.05 | 0.298 | Guru fraction |
| TUBAL3 | TXNDC9 | 0.04 | 0.268 | bioplex (TUBAL3,TXNDC9) bioplex_WMM youn_WMM gupta_WMM |
| TUBAL3 | CCT6B | 0.005 | 0.01 | bioplex (TUBAL3) bioplex_WMM youn_WMM gupta_WMM |
Images
Click to enlarge
Complex HuMAP2_02430 has an average edge precision of 0.232 which is ranked 5652 out of all 6965 complexes.
Related Complexes
| Genename | Complexes |
|---|---|
| TXNDC9 | HuMAP2_01395 HuMAP2_02430 HuMAP2_02480 HuMAP2_04444 HuMAP2_04472 HuMAP2_05380 |
| CYP27A1 | HuMAP2_02430 HuMAP2_03738 HuMAP2_04444 HuMAP2_05380 |
| CCT6B | HuMAP2_02430 HuMAP2_02480 HuMAP2_03738 HuMAP2_04444 HuMAP2_05380 HuMAP2_06101 |
| TUBAL3 | HuMAP2_01395 HuMAP2_02430 HuMAP2_04444 HuMAP2_04472 HuMAP2_05380 |