hu.MAP 2.0: Complex View
Human Protein Complex Map
Search for a protein
Complex: HuMAP2_02448
Confidence: Medium
Proteins| Genename | Protein Name | Links |
|---|---|---|
| GNPTG | N-acetylglucosamine-1-phosphotransferase subunit gamma (GlcNAc-1-phosphotransferase subunit gamma) (UDP-N-acetylglucosamine-1-phosphotransferase subunit gamma) | UniProt NCBI |
| GNPTAB | N-acetylglucosamine-1-phosphotransferase subunits alpha/beta (EC 2.7.8.17) (GlcNAc-1-phosphotransferase subunits alpha/beta) (Stealth protein GNPTAB) (UDP-N-acetylglucosamine-1-phosphotransferase subunits alpha/beta) [Cleaved into: N-acetylglucosamine-1-phosphotransferase subunit alpha; N-acetylglucosamine-1-phosphotransferase subunit beta] | UniProt NCBI |
| IGSF6 | Immunoglobulin superfamily member 6 (IgSF6) (Protein DORA) | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| HP:0003333 | 8.83967473292e-06 | 0.666666666667 | GNPTG GNPTAB | Increased serum beta-hexosaminidase |
| HP:0003538 | 8.83967473292e-06 | 0.666666666667 | GNPTG GNPTAB | Increased serum iduronate sulfatase activity |
| HP:0002869 | 0.00135150150266 | 0.666666666667 | GNPTG GNPTAB | Flared iliac wings |
| HP:0000943 | 0.0016781848244 | 0.666666666667 | GNPTG GNPTAB | Dysostosis multiplex |
| KEGG:04142 | 0.00307537091529 | 0.666666666667 | GNPTG GNPTAB | Lysosome |
| HP:0011867 | 0.00995061979035 | 0.666666666667 | GNPTG GNPTAB | Abnormality of the wing of the ilium |
| HP:0001659 | 0.0135801907106 | 0.666666666667 | GNPTG GNPTAB | Aortic regurgitation |
| HP:0007759 | 0.0183346678183 | 0.666666666667 | GNPTG GNPTAB | Opacification of the corneal stroma |
| HP:0011492 | 0.0200772827833 | 0.666666666667 | GNPTG GNPTAB | Abnormality of corneal stroma |
| HP:0002867 | 0.0271411575623 | 0.666666666667 | GNPTG GNPTAB | Abnormality of the ilium |
| GO:0046835 | 0.0378589948753 | 0.666666666667 | GNPTG GNPTAB | carbohydrate phosphorylation |
| HP:0031652 | 0.0462248590062 | 0.666666666667 | GNPTG GNPTAB | Abnormal aortic valve physiology |
Edges
| Protein 1 | Protein 2 | Score | Precision | Evidence |
|---|---|---|---|---|
| IGSF6 | GNPTAB | 0.034 | 0.257 | bioplex (IGSF6) bioplex_WMM |
| GNPTG | GNPTAB | 0.025 | 0.217 | hein_WMM bioplex (GNPTG) bioplex_WMM |
| IGSF6 | GNPTG | 0.003 | 0.015 | bioplex (IGSF6) bioplex_WMM |
Images
Click to enlarge
Complex HuMAP2_02448 has an average edge precision of 0.163 which is ranked 6597 out of all 6965 complexes.
Related Complexes
| Genename | Complexes |
|---|---|
| GNPTG | HuMAP2_02448 HuMAP2_03601 HuMAP2_04342 HuMAP2_06160 |
| GNPTAB | HuMAP2_02448 HuMAP2_03711 |
| IGSF6 | HuMAP2_02448 HuMAP2_03711 |