hu.MAP 2.0: Complex View
Human Protein Complex Map
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Complex: HuMAP2_02453
Confidence: Medium
Proteins| Genename | Protein Name | Links |
|---|---|---|
| SELENOK | Selenoprotein K (SelK) | UniProt NCBI |
| CISD2 | CDGSH iron-sulfur domain-containing protein 2 (Endoplasmic reticulum intermembrane small protein) (MitoNEET-related 1 protein) (Miner1) (Nutrient-deprivation autophagy factor-1) (NAF-1) | UniProt NCBI |
| UGT8 | 2-hydroxyacylsphingosine 1-beta-galactosyltransferase (EC 2.4.1.47) (Ceramide UDP-galactosyltransferase) (Cerebroside synthase) (UDP-galactose-ceramide galactosyltransferase) | UniProt NCBI |
| TSPO | Translocator protein (Mitochondrial benzodiazepine receptor) (PKBS) (Peripheral-type benzodiazepine receptor) (PBR) | UniProt NCBI |
| VDAC1 | Voltage-dependent anion-selective channel protein 1 (VDAC-1) (hVDAC1) (Outer mitochondrial membrane protein porin 1) (Plasmalemmal porin) (Porin 31HL) (Porin 31HM) | UniProt NCBI |
| PRAF2 | PRA1 family protein 2 | UniProt NCBI |
| HMOX2 | Heme oxygenase 2 (HO-2) (EC 1.14.14.18) | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| KEGG:04979 | 0.00887927082173 | 0.285714285714 | TSPO VDAC1 | Cholesterol metabolism |
| CORUM:7219 | 0.0499886427319 | 0.142857142857 | SELENOK | DHHC6-SELK complex |
| CORUM:7275 | 0.0499886427319 | 0.142857142857 | CISD2 | BCL2-CISD2 complex |
| CORUM:7418 | 0.0499886427319 | 0.142857142857 | VDAC1 | HK1-VDAC1 complex |
| CORUM:7529 | 0.0499886427319 | 0.142857142857 | VDAC1 | APP-Abeta42-VDAC1 complex |
Edges
| Protein 1 | Protein 2 | Score | Precision | Evidence |
|---|---|---|---|---|
| UGT8 | HMOX2 | 0.22 | 0.466 | bioplex (HMOX2) bioplex_WMM youn_WMM gupta_WMM |
| CISD2 | HMOX2 | 0.136 | 0.406 | bioplex (HMOX2) bioplex_WMM youn_WMM gupta_WMM |
| SELENOK | HMOX2 | 0.062 | 0.342 | bioplex (HMOX2) bioplex_WMM |
| HMOX2 | PRAF2 | 0.033 | 0.252 | bioplex (HMOX2) bioplex_WMM youn_WMM gupta_WMM |
| VDAC1 | CISD2 | 0.025 | 0.21 | bioplex_WMM Guru youn_WMM gupta_WMM fraction treiber_WMM |
| VDAC1 | TSPO | 0.02 | 0.185 | bioplex_WMM Guru boldt fraction boldt_WMM |
| CISD2 | PRAF2 | 0.007 | 0.009 | bioplex_WMM youn_WMM gupta_WMM WMM_only |
| SELENOK | PRAF2 | 0.007 | 0.011 | bioplex_WMM WMM_only |
| CISD2 | SELENOK | 0.007 | 0.005 | bioplex_WMM WMM_only |
| UGT8 | SELENOK | 0.007 | 0.006 | bioplex_WMM WMM_only |
| VDAC1 | UGT8 | 0.007 | 0.005 | bioplex_WMM gupta_WMM WMM_only |
| VDAC1 | HMOX2 | 0.007 | 0.006 | bioplex_WMM gupta_WMM WMM_only |
| UGT8 | PRAF2 | 0.006 | 0.001 | bioplex_WMM youn_WMM gupta_WMM WMM_only |
| CISD2 | UGT8 | 0.006 | 0.005 | bioplex_WMM youn_WMM gupta_WMM WMM_only |
| VDAC1 | PRAF2 | 0.006 | 0.006 | bioplex_WMM youn_WMM gupta_WMM WMM_only |
Images
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Complex HuMAP2_02453 has an average edge precision of 0.128 which is ranked 6839 out of all 6965 complexes.
Related Complexes