hu.MAP 2.0: Complex View
Human Protein Complex Map
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Complex: HuMAP2_02456
Confidence: Very High
Proteins| Genename | Protein Name | Links |
|---|---|---|
| NFE2L1 | Endoplasmic reticulum membrane sensor NFE2L1 (Locus control region-factor 1) (LCR-F1) (Nuclear factor erythroid 2-related factor 1) (NF-E2-related factor 1) (NFE2-related factor 1) (Nuclear factor, erythroid derived 2, like 1) (Protein NRF1, p120 form) (Transcription factor 11) (TCF-11) [Cleaved into: Transcription factor NRF1 (Protein NRF1, p110 form)] | UniProt NCBI |
| MAFF | Transcription factor MafF (U-Maf) (V-maf musculoaponeurotic fibrosarcoma oncogene homolog F) | UniProt NCBI |
| BACH2 | Transcription regulator protein BACH2 (BTB and CNC homolog 2) | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| CORUM:7489 | 0.0499776345577 | 0.333333333333 | NFE2L1 | EglN2-NRF1-PGC1alpha complex |
Edges
| Protein 1 | Protein 2 | Score | Precision | Evidence |
|---|---|---|---|---|
| MAFF | BACH2 | 0.998 | 0.939 | bioplex (MAFF) bioplex_WMM |
| MAFF | NFE2L1 | 0.974 | 0.886 | bioplex (MAFF) bioplex_WMM |
| BACH2 | NFE2L1 | 0.009 | 0.107 | bioplex_WMM WMM_only |
Images
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Complex HuMAP2_02456 has an average edge precision of 0.644 which is ranked 1675 out of all 6965 complexes.
Related Complexes
| Genename | Complexes |
|---|---|
| NFE2L1 | HuMAP2_01275 HuMAP2_02263 HuMAP2_02456 HuMAP2_05582 |
| MAFF | HuMAP2_01275 HuMAP2_01303 HuMAP2_02263 HuMAP2_02456 HuMAP2_05582 |
| BACH2 | HuMAP2_01275 HuMAP2_01303 HuMAP2_02263 HuMAP2_02456 HuMAP2_04193 HuMAP2_05582 HuMAP2_05753 |