hu.MAP 2.0: Complex View
Human Protein Complex Map
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Complex: HuMAP2_02475
Confidence: Medium High
Proteins| Genename | Protein Name | Links |
|---|---|---|
| KRT2 | Keratin, type II cytoskeletal 2 epidermal (Cytokeratin-2e) (CK-2e) (Epithelial keratin-2e) (Keratin-2 epidermis) (Keratin-2e) (K2e) (Type-II keratin Kb2) | UniProt NCBI |
| KRT10 | Keratin, type I cytoskeletal 10 (Cytokeratin-10) (CK-10) (Keratin-10) (K10) | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| HP:0007475 | 2.00365960613e-05 | 1.0 | KRT2 KRT10 | Congenital bullous ichthyosiform erythroderma |
| HP:0007431 | 0.000921683418819 | 1.0 | KRT2 KRT10 | Congenital ichthyosiform erythroderma |
| HP:0011124 | 0.0053297345523 | 1.0 | KRT2 KRT10 | Abnormality of epidermal morphology |
| REAC:R-HSA-6809371 | 0.00796566421667 | 1.0 | KRT2 KRT10 | Formation of the cornified envelope |
| HP:0008066 | 0.00829849020205 | 1.0 | KRT2 KRT10 | Abnormal blistering of the skin |
| REAC:R-HSA-6805567 | 0.0136219059022 | 1.0 | KRT2 KRT10 | Keratinization |
| HP:0010783 | 0.0152278130066 | 1.0 | KRT2 KRT10 | Erythema |
| GO:0030280 | 0.0247952876258 | 1.0 | KRT2 KRT10 | structural constituent of epidermis |
| HP:0008064 | 0.0254665135939 | 1.0 | KRT2 KRT10 | Ichthyosis |
| HP:0000982 | 0.0288727349243 | 1.0 | KRT2 KRT10 | Palmoplantar keratoderma |
Edges
| Protein 1 | Protein 2 | Score | Precision | Evidence |
|---|---|---|---|---|
| KRT10 | KRT2 | 0.459 | 0.597 | youn_WMM gupta_WMM fraction boldt_WMM |
Images
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Complex HuMAP2_02475 has an average edge precision of 0.597 which is ranked 1957 out of all 6965 complexes.
Related Complexes
| Genename | Complexes |
|---|---|
| KRT2 | HuMAP2_02475 |
| KRT10 | HuMAP2_00512 HuMAP2_02475 |