hu.MAP 2.0: Complex View
Human Protein Complex Map
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Complex: HuMAP2_02478
Confidence: Extremely High
Proteins| Genename | Protein Name | Links |
|---|---|---|
| SEC24C | Protein transport protein Sec24C (SEC24-related protein C) | UniProt NCBI |
| SEC23A | Protein transport protein Sec23A (hSec23A) (SEC23-related protein A) | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| REAC:R-HSA-983170 | 0.000502777038712 | 1.0 | SEC24C SEC23A | Antigen Presentation: Folding, assembly and peptide loading of class I MHC |
| REAC:R-HSA-5694530 | 0.000588249135293 | 1.0 | SEC24C SEC23A | Cargo concentration in the ER |
| WP:WP1982 | 0.000799186956535 | 1.0 | SEC24C SEC23A | Sterol Regulatory Element-Binding Proteins (SREBP) signalling |
| KEGG:04141 | 0.00178666132548 | 1.0 | SEC24C SEC23A | Protein processing in endoplasmic reticulum |
| REAC:R-HSA-1655829 | 0.00205300624141 | 1.0 | SEC24C SEC23A | Regulation of cholesterol biosynthesis by SREBP (SREBF) |
| REAC:R-HSA-204005 | 0.00306693993615 | 1.0 | SEC24C SEC23A | COPII-mediated vesicle transport |
| REAC:R-HSA-2132295 | 0.011178409494 | 1.0 | SEC24C SEC23A | MHC class II antigen presentation |
| REAC:R-HSA-8957322 | 0.0131978972662 | 1.0 | SEC24C SEC23A | Metabolism of steroids |
| REAC:R-HSA-199977 | 0.0172553079686 | 1.0 | SEC24C SEC23A | ER to Golgi Anterograde Transport |
| REAC:R-HSA-948021 | 0.0237914094719 | 1.0 | SEC24C SEC23A | Transport to the Golgi and subsequent modification |
| HP:0000670 | 0.0315676570945 | 1.0 | SEC24C SEC23A | Carious teeth |
| GO:0090110 | 0.0410249304355 | 1.0 | SEC24C SEC23A | COPII-coated vesicle cargo loading |
| HP:0000426 | 0.0430118928782 | 1.0 | SEC24C SEC23A | Prominent nasal bridge |
| HP:0005692 | 0.0462878763342 | 1.0 | SEC24C SEC23A | Joint hyperflexibility |
| GO:0030127 | 0.0473364581948 | 1.0 | SEC24C SEC23A | COPII vesicle coat |
| HP:0000272 | 0.0479709504034 | 1.0 | SEC24C SEC23A | Malar flattening |
| HP:0008444 | 0.0497341708567 | 0.5 | SEC23A | Posterior wedging of vertebral bodies |
| HP:0005336 | 0.0497341708567 | 0.5 | SEC23A | Forehead hyperpigmentation |
| CORUM:7139 | 0.0499173803268 | 0.5 | SEC23A | SEC23-SEC24 adaptor complex |
Edges
| Protein 1 | Protein 2 | Score | Precision | Evidence |
|---|---|---|---|---|
| SEC24C | SEC23A | 1.0 | 0.949 | hein_WMM bioplex_WMM youn_WMM hein (SEC24C) Malo gupta_WMM fraction treiber_WMM |
Images
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Complex HuMAP2_02478 has an average edge precision of 0.949 which is ranked 5 out of all 6965 complexes.
Related Complexes
| Genename | Complexes |
|---|---|
| SEC24C | HuMAP2_00758 HuMAP2_01054 HuMAP2_02478 HuMAP2_02576 HuMAP2_05176 HuMAP2_05341 HuMAP2_06134 |
| SEC23A | HuMAP2_00758 HuMAP2_02478 HuMAP2_05176 HuMAP2_06365 |