hu.MAP 2.0: Complex View
Human Protein Complex Map
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Complex: HuMAP2_02505
Confidence: Extremely High
Proteins| Genename | Protein Name | Links |
|---|---|---|
| ILK | Integrin-linked protein kinase (EC 2.7.11.1) (59 kDa serine/threonine-protein kinase) (ILK-1) (ILK-2) (p59ILK) | UniProt NCBI |
| PARVA | Alpha-parvin (Actopaxin) (CH-ILKBP) (Calponin-like integrin-linked kinase-binding protein) (Matrix-remodeling-associated protein 2) | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| CORUM:6919 | 5.02777038712e-06 | 1.0 | ILK PARVA | ILK-LIMS1-PARVA complex |
| CORUM:6920 | 5.02777038712e-06 | 1.0 | ILK PARVA | ILK-LIMS2-PARVA complex |
| REAC:R-HSA-446343 | 1.00555407742e-05 | 1.0 | ILK PARVA | Localization of the PINCH-ILK-PARVIN complex to focal adhesions |
| REAC:R-HSA-446353 | 0.000256416289743 | 1.0 | ILK PARVA | Cell-extracellular matrix interactions |
| WP:WP2572 | 0.000727651340845 | 1.0 | ILK PARVA | Primary Focal Segmental Glomerulosclerosis FSGS |
| KEGG:04510 | 0.00259201576911 | 1.0 | ILK PARVA | Focal adhesion |
| REAC:R-HSA-446728 | 0.004164669804 | 1.0 | ILK PARVA | Cell junction organization |
| WP:WP306 | 0.00654923464894 | 1.0 | ILK PARVA | Focal Adhesion |
| REAC:R-HSA-1500931 | 0.00880362594785 | 1.0 | ILK PARVA | Cell-Cell communication |
| CORUM:6510 | 0.0499173803268 | 0.5 | ILK | ILK-SERCA2A-PLN complex |
Edges
| Protein 1 | Protein 2 | Score | Precision | Evidence |
|---|---|---|---|---|
| ILK | PARVA | 1.0 | 0.949 | hein_WMM bioplex (ILK,PARVA) bioplex_WMM Guru hein (ILK) Malo fraction treiber_WMM |
Images
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Complex HuMAP2_02505 has an average edge precision of 0.949 which is ranked 5 out of all 6965 complexes.
Related Complexes
| Genename | Complexes |
|---|---|
| ILK | HuMAP2_01374 HuMAP2_02505 HuMAP2_06435 HuMAP2_06595 |
| PARVA | HuMAP2_01374 HuMAP2_02505 HuMAP2_06435 HuMAP2_06595 |