hu.MAP 2.0: Complex View
Human Protein Complex Map
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Complex: HuMAP2_02521
Confidence: Extremely High
Proteins| Genename | Protein Name | Links |
|---|---|---|
| ATP5PD | ATP synthase subunit d, mitochondrial (ATPase subunit d) (ATP synthase peripheral stalk subunit d) | UniProt NCBI |
| ATP5PO | ATP synthase subunit O, mitochondrial (ATP synthase peripheral stalk subunit OSCP) (Oligomycin sensitivity conferral protein) (OSCP) | UniProt NCBI |
| ATP5PB | ATP synthase F(0) complex subunit B1, mitochondrial (ATP synthase peripheral stalk-membrane subunit b) (ATP synthase proton-transporting mitochondrial F(0) complex subunit B1) (ATP synthase subunit b) (ATPase subunit b) | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| CORUM:563 | 1.26199510107e-07 | 1.0 | ATP5PD ATP5PB ATP5PO | F1F0-ATP synthase, mitochondrial |
| REAC:R-HSA-163210 | 3.66871079381e-07 | 1.0 | ATP5PD ATP5PB ATP5PO | Formation of ATP by chemiosmotic coupling |
| WP:WP623 | 1.68980520707e-06 | 1.0 | ATP5PD ATP5PB ATP5PO | Oxidative phosphorylation |
| REAC:R-HSA-8949613 | 1.82536345868e-06 | 1.0 | ATP5PD ATP5PB ATP5PO | Cristae formation |
| KEGG:00190 | 8.02679835688e-06 | 1.0 | ATP5PD ATP5PB ATP5PO | Oxidative phosphorylation |
| WP:WP111 | 8.35827186966e-06 | 1.0 | ATP5PD ATP5PB ATP5PO | Electron Transport Chain (OXPHOS system in mitochondria) |
| KEGG:05012 | 9.78855844223e-06 | 1.0 | ATP5PD ATP5PB ATP5PO | Parkinson disease |
| KEGG:05010 | 1.79503216233e-05 | 1.0 | ATP5PD ATP5PB ATP5PO | Alzheimer disease |
| KEGG:05016 | 2.6860646392e-05 | 1.0 | ATP5PD ATP5PB ATP5PO | Huntington disease |
| KEGG:04714 | 4.51020686166e-05 | 1.0 | ATP5PD ATP5PB ATP5PO | Thermogenesis |
| REAC:R-HSA-1592230 | 4.93369666261e-05 | 1.0 | ATP5PD ATP5PB ATP5PO | Mitochondrial biogenesis |
| GO:0005753 | 0.000103533176666 | 1.0 | ATP5PD ATP5PB ATP5PO | mitochondrial proton-transporting ATP synthase complex |
| GO:0045259 | 0.000103533176666 | 1.0 | ATP5PD ATP5PB ATP5PO | proton-transporting ATP synthase complex |
| REAC:R-HSA-163200 | 0.000113954833063 | 1.0 | ATP5PD ATP5PB ATP5PO | Respiratory electron transport, ATP synthesis by chemiosmotic coupling, and heat production by uncoupling proteins. |
| GO:0042776 | 0.000160839698137 | 1.0 | ATP5PD ATP5PB ATP5PO | mitochondrial ATP synthesis coupled proton transport |
| GO:0015986 | 0.000183816797871 | 1.0 | ATP5PD ATP5PB ATP5PO | ATP synthesis coupled proton transport |
| GO:0015985 | 0.000183816797871 | 1.0 | ATP5PD ATP5PB ATP5PO | energy coupled proton transport, down electrochemical gradient |
| REAC:R-HSA-1428517 | 0.000330512177188 | 1.0 | ATP5PD ATP5PB ATP5PO | The citric acid (TCA) cycle and respiratory electron transport |
| GO:0042407 | 0.000368723418654 | 1.0 | ATP5PD ATP5PB ATP5PO | cristae formation |
| GO:0006754 | 0.000648444632805 | 1.0 | ATP5PD ATP5PB ATP5PO | ATP biosynthetic process |
| GO:0009206 | 0.000766145507331 | 1.0 | ATP5PD ATP5PB ATP5PO | purine ribonucleoside triphosphate biosynthetic process |
| GO:0009145 | 0.000766145507331 | 1.0 | ATP5PD ATP5PB ATP5PO | purine nucleoside triphosphate biosynthetic process |
| GO:0009201 | 0.000968126020406 | 1.0 | ATP5PD ATP5PB ATP5PO | ribonucleoside triphosphate biosynthetic process |
| GO:0016469 | 0.000968126020406 | 1.0 | ATP5PD ATP5PB ATP5PO | proton-transporting two-sector ATPase complex |
| GO:0007007 | 0.00104259725275 | 1.0 | ATP5PD ATP5PB ATP5PO | inner mitochondrial membrane organization |
| GO:0009205 | 0.0015707980909 | 1.0 | ATP5PD ATP5PB ATP5PO | purine ribonucleoside triphosphate metabolic process |
| REAC:R-HSA-1852241 | 0.00160990717739 | 1.0 | ATP5PD ATP5PB ATP5PO | Organelle biogenesis and maintenance |
| GO:0009142 | 0.00167324144465 | 1.0 | ATP5PD ATP5PB ATP5PO | nucleoside triphosphate biosynthetic process |
| GO:0009199 | 0.00189129684568 | 1.0 | ATP5PD ATP5PB ATP5PO | ribonucleoside triphosphate metabolic process |
| GO:0009144 | 0.00200709053011 | 1.0 | ATP5PD ATP5PB ATP5PO | purine nucleoside triphosphate metabolic process |
| GO:1902600 | 0.00455146375597 | 1.0 | ATP5PD ATP5PB ATP5PO | proton transmembrane transport |
| GO:0009141 | 0.00475834847216 | 1.0 | ATP5PD ATP5PB ATP5PO | nucleoside triphosphate metabolic process |
| GO:1990542 | 0.0103137207675 | 1.0 | ATP5PD ATP5PB ATP5PO | mitochondrial transmembrane transport |
| KEGG:01100 | 0.0105851300972 | 1.0 | ATP5PD ATP5PB ATP5PO | Metabolic pathways |
| GO:0007006 | 0.0190659069388 | 1.0 | ATP5PD ATP5PB ATP5PO | mitochondrial membrane organization |
| GO:0045263 | 0.020283420769 | 0.666666666667 | ATP5PD ATP5PB | proton-transporting ATP synthase complex, coupling factor F(o) |
| GO:0033177 | 0.020283420769 | 0.666666666667 | ATP5PD ATP5PB | proton-transporting two-sector ATPase complex, proton-transporting domain |
| GO:0000276 | 0.020283420769 | 0.666666666667 | ATP5PD ATP5PB | mitochondrial proton-transporting ATP synthase complex, coupling factor F(o) |
| GO:0098800 | 0.0218385980648 | 1.0 | ATP5PD ATP5PB ATP5PO | inner mitochondrial membrane protein complex |
| GO:0006119 | 0.0248678516681 | 1.0 | ATP5PD ATP5PB ATP5PO | oxidative phosphorylation |
| GO:0009152 | 0.0268132763851 | 1.0 | ATP5PD ATP5PB ATP5PO | purine ribonucleotide biosynthetic process |
| GO:0009260 | 0.0317414555944 | 1.0 | ATP5PD ATP5PB ATP5PO | ribonucleotide biosynthetic process |
| GO:0006164 | 0.0364177948924 | 1.0 | ATP5PD ATP5PB ATP5PO | purine nucleotide biosynthetic process |
| GO:0046390 | 0.0364177948924 | 1.0 | ATP5PD ATP5PB ATP5PO | ribose phosphate biosynthetic process |
| GO:0072522 | 0.0461431021058 | 1.0 | ATP5PD ATP5PB ATP5PO | purine-containing compound biosynthetic process |
Edges
| Protein 1 | Protein 2 | Score | Precision | Evidence |
|---|---|---|---|---|
| ATP5PD | ATP5PB | 1.0 | 0.949 | hein_WMM bioplex (ATP5PB) bioplex_WMM Guru boldt youn_WMM gupta_WMM fraction boldt_WMM |
| ATP5PB | ATP5PO | 1.0 | 0.949 | hein_WMM bioplex (ATP5PB) bioplex_WMM Guru boldt youn_WMM gupta_WMM fraction boldt_WMM treiber_WMM |
| ATP5PD | ATP5PO | 0.997 | 0.929 | hein_WMM bioplex_WMM Guru boldt youn_WMM gupta_WMM fraction boldt_WMM |
Images
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Complex HuMAP2_02521 has an average edge precision of 0.942 which is ranked 379 out of all 6965 complexes.
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