hu.MAP 2.0: Complex View
Human Protein Complex Map
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Complex: HuMAP2_02525
Confidence: Very High
Proteins| Genename | Protein Name | Links |
|---|---|---|
| NDUFB11 | NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 11, mitochondrial (Complex I-ESSS) (CI-ESSS) (NADH-ubiquinone oxidoreductase ESSS subunit) (Neuronal protein 17.3) (Np17.3) (p17.3) | UniProt NCBI |
| NDUFB7 | NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 7 (Cell adhesion protein SQM1) (Complex I-B18) (CI-B18) (NADH-ubiquinone oxidoreductase B18 subunit) | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| CORUM:2914 | 0.000175971963549 | 1.0 | NDUFB11 NDUFB7 | Respiratory chain complex I (beta subunit) mitochondrial |
| WP:WP4324 | 0.000513417075107 | 1.0 | NDUFB11 NDUFB7 | Mitochondrial complex I assembly model OXPHOS system |
| KEGG:00190 | 0.00100713074717 | 1.0 | NDUFB11 NDUFB7 | Oxidative phosphorylation |
| KEGG:05012 | 0.00114894316007 | 1.0 | NDUFB11 NDUFB7 | Parkinson disease |
| KEGG:04723 | 0.0012614301666 | 1.0 | NDUFB11 NDUFB7 | Retrograde endocannabinoid signaling |
| KEGG:04932 | 0.00128068864242 | 1.0 | NDUFB11 NDUFB7 | Non-alcoholic fatty liver disease (NAFLD) |
| CORUM:178 | 0.00130722030065 | 1.0 | NDUFB11 NDUFB7 | Respiratory chain complex I (holoenzyme), mitochondrial |
| KEGG:05010 | 0.00171881896746 | 1.0 | NDUFB11 NDUFB7 | Alzheimer disease |
| REAC:R-HSA-6799198 | 0.00222227451111 | 1.0 | NDUFB11 NDUFB7 | Complex I biogenesis |
| KEGG:05016 | 0.00224682217969 | 1.0 | NDUFB11 NDUFB7 | Huntington disease |
| KEGG:04714 | 0.00317122901933 | 1.0 | NDUFB11 NDUFB7 | Thermogenesis |
| WP:WP4396 | 0.00347096768628 | 1.0 | NDUFB11 NDUFB7 | Nonalcoholic fatty liver disease |
| REAC:R-HSA-611105 | 0.00732546145404 | 1.0 | NDUFB11 NDUFB7 | Respiratory electron transport |
| REAC:R-HSA-163200 | 0.011178409494 | 1.0 | NDUFB11 NDUFB7 | Respiratory electron transport, ATP synthesis by chemiosmotic coupling, and heat production by uncoupling proteins. |
| REAC:R-HSA-1428517 | 0.0226752444459 | 1.0 | NDUFB11 NDUFB7 | The citric acid (TCA) cycle and respiratory electron transport |
| HP:0007572 | 0.0497341708567 | 0.5 | NDUFB11 | Hyperpigmented streaks |
Edges
| Protein 1 | Protein 2 | Score | Precision | Evidence |
|---|---|---|---|---|
| NDUFB11 | NDUFB7 | 0.739 | 0.738 | hein_WMM bioplex (NDUFB11) bioplex_WMM |
Images
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Complex HuMAP2_02525 has an average edge precision of 0.738 which is ranked 1213 out of all 6965 complexes.
Related Complexes
| Genename | Complexes |
|---|---|
| NDUFB11 | HuMAP2_00091 HuMAP2_01373 HuMAP2_01573 HuMAP2_01600 HuMAP2_02247 HuMAP2_02525 HuMAP2_04543 HuMAP2_06566 |
| NDUFB7 | HuMAP2_00091 HuMAP2_01373 HuMAP2_01573 HuMAP2_01600 HuMAP2_02247 HuMAP2_02525 |